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Completed Phase 2 Interventional

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

ClinicalTrials.gov ID: NCT06703346

Public ClinicalTrials.gov record NCT06703346. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This trial will evaluate safety and efficacy of human engineered T-cell therapies, in participants with advanced tumors. This trial is a sub study of the Master study NCT03967223.

Study identification

NCT ID
NCT06703346
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
USWM CT, LLC
Industry
Enrollment
82 participants

Conditions and interventions

Eligibility (public fields only)

Age range
10 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2019 (Actual)
Primary completion
Mar 1, 2024 (Actual)
Completion
Jul 24, 2026 (Actual)
Last update posted
Aug 13, 2026

2019 – 2026

United States locations

U.S. sites
24
U.S. states
20
U.S. cities
22
Facility City State ZIP Site status
City of Hope National Medical Center Duarte California 91010 —
Stanford Hospital and Clinics Stanford California 94305 —
Sarah Cannon Research Institute Denver Colorado 80218 —
Mayo Clinic Jacksonville Jacksonville Florida 32224 —
University of Chicago Chicago Illinois 60637 —
University of Iowa College of Medicine Iowa City Iowa 52242-1009 —
Dana Farber Cancer Institute Boston Massachusetts 02114 —
Massachusetts General Hospital Boston Massachusetts 02114 —
University of Michigan Medical Center Ann Arbor Michigan 48109 —
Minnesota Oncology Hematology Minneapolis Minnesota 55455 —
Mayo Clinic Rochester Rochester Minnesota 55905 —
Washington University St Louis Missouri 63110 —
Memorial Sloan Kettering cancer center New York New York 10065 —
Duke University Medical Center Durham North Carolina 27710 —
Ohio State University-Columbus Columbus Ohio 43210 —
Oregon Health and Science University Portland Oregon 97239 —
University of Pittsburgh, Hillman Cancer centre Pittsburgh Pennsylvania 15232 —
Sarah Cannon Research Institute Nashville Tennessee 37203 —
University Of Texas Southwestern Medical Center Dallas Texas 75390-8565 —
University of Texas Southwestern Medical Center Dallas Texas 75390-9063 —
University of Utah Salt Lake City Utah 84112 —
Virginia Commonwealth University Richmond Virginia 23298 —
Fred Hutchinson Cancer Research Center Seattle Washington 98109-1024 —
Froedtert Hospital Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06703346, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 13, 2026 · Synced Oct 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06703346 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →