A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
Public ClinicalTrials.gov record NCT06712654. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, and Serum Phosphate Lowering Effect of Fixed Dose AP306 in Participants With Hyperphosphatemia Receiving Maintenance Hemodialysis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is being conducted to characterize the safety, tolerability, and efficacy of AP306 at fixed doses in adults with hyperphosphatemia receiving maintenance hemodialysis.
Study identification
- NCT ID
- NCT06712654
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 168 participants
Conditions and interventions
Conditions
Interventions
- AP306 75 mg BID Drug
- AP306 125 mg BID Drug
- AP306 150 mg BID Drug
- AP306 75 mg TID Drug
- AP306 100 mg TID Drug
- AP306 125 mg TID Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2026
- Primary completion
- Feb 27, 2027
- Completion
- Mar 30, 2027
- Last update posted
- Aug 25, 2026
2026 – 2027
United States locations
- U.S. sites
- 24
- U.S. states
- 15
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Apogee Clinical Research, LLC | Huntsville | Alabama | 35801 | Recruiting |
| California Institute of Renal Research | Chula Vista | California | 91910 | Recruiting |
| Academic Medical Research Institute | Los Angeles | California | 90022 | Recruiting |
| North America Research Institute | San Dimas | California | 91773 | Recruiting |
| Colorado Kidney Care | Denver | Colorado | 80220 | Recruiting |
| DaVita Clinical Research | Middlebury | Connecticut | 06762 | Recruiting |
| PACT Kidney Care | Orange | Connecticut | 06477 | Recruiting |
| US Renal Care - Fort Myers South | Fort Myers | Florida | 33912 | Recruiting |
| Nephrology & Hypertension Specialists | Dalton | Georgia | 30720 | Recruiting |
| St. Clair Nephrology Research | Shelby | Michigan | 48315 | Recruiting |
| DaVita Clinical Research Edina | Edina | Minnesota | 55435 | Recruiting |
| Johnson County Clinical Trials | Kansas City | Missouri | 64111 | Recruiting |
| DaVita Clinical Research | Las Vegas | Nevada | 89107 | Recruiting |
| R1 Therapeutics Clinical Trial Site | Albuquerque | New Mexico | 87109 | Recruiting |
| NY Kidney & Hypertension Medicine | Ridgewood | New York | 11385 | Recruiting |
| US Renal Care - Alexis | Toledo | Ohio | 43613 | Recruiting |
| Sunbeam Research | Greenville | Texas | 75402 | Recruiting |
| DaVita Clinical Research | Houston | Texas | 77054 | Recruiting |
| Gamma Medical Research | McAllen | Texas | 78503 | Recruiting |
| US Renal Care - South San Antonio | San Antonio | Texas | 35801 | Recruiting |
| US Renal Care - Westover Hills | San Antonio | Texas | 78251 | Recruiting |
| DaVita Clinical Research San Antonio | San Antonio | Texas | 78258 | Recruiting |
| US Renal Care | Waxahachie | Texas | 75165 | Recruiting |
| DaVita Clinical Research Norfolk | Norfolk | Virginia | 23502 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06712654, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 25, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06712654 live on ClinicalTrials.gov.