A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy
Public ClinicalTrials.gov record NCT06722157. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-masked, Active-controlled, Multicenter Study to Evaluate Efficacy and Safety of Two Regimens of Intravitreal BI 771716 Against Pegcetacoplan in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration VERDANT Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan. BI 771716 is being developed to treat people with geographic atrophy. Pegcetacoplan is a medicine already used to treat people with geographic atrophy. In this study, participants receive either BI 771716 or pegcetacoplan as injections in the eye. Participants are in the study for a little longer than a year and visit the study site every 4 weeks. At the visits, the study doctor checks the eyes of the participants. The results are compared between the groups of participants to see whether the treatment works. The study doctor also regularly checks participants' health and takes note of any unwanted effects.
Study identification
- NCT ID
- NCT06722157
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 202 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 6, 2025 (Actual)
- Primary completion
- Oct 28, 2026 (Estimated)
- Completion
- Oct 28, 2026 (Estimated)
- Last update posted
- May 14, 2026
2025 – 2026
United States locations
- U.S. sites
- 46
- U.S. states
- 24
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants | Gilbert | Arizona | 85297 | — |
| Associated Retina Consultants, Ltd. | Phoenix | Arizona | 85020 | — |
| Phoenix Retina Associates | Phoenix | Arizona | 85050 | — |
| Retina Macula Institute of Arizona | Scottsdale | Arizona | 85255 | — |
| Global Research Management | Glendale | California | 91204 | — |
| Retina Associates of Southern California | Huntington Beach | California | 92647 | — |
| Retinal Consultants Medical Group, Inc | Modesto | California | 95356 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| Retina Consultants of San Diego | Poway | California | 92064 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95825 | — |
| Bay Area Retina Associates - Walnut Creek | Walnut Creek | California | 94598 | — |
| Colorado Retina Associates | Lakewood | Colorado | 80228 | — |
| Connecticut Eye Consultants, PC | Danbury | Connecticut | 06810 | — |
| Retina Group of New England, PC | Waterford | Connecticut | 06385 | — |
| Rand Eye Institute | Deerfield Beach | Florida | 33064 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| Eye Associates of Pinellas | Pinellas Park | Florida | 33782 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| Southeast Retina Center, PC | Augusta | Georgia | 30909 | — |
| University Retina and Macula Associates | Lemont | Illinois | 60439 | — |
| Illinois Retina Associates - Oak Park | Oak Park | Illinois | 60304 | — |
| Butchertown Clinical Trials | Louisville | Kentucky | 40206 | — |
| Mid Atlantic Retina Specialists | Hagerstown | Maryland | 21740 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Retina Consultants of Minnesota | Edina | Minnesota | 55435 | — |
| Mississippi Retina Associates | Madison | Mississippi | 39110 | — |
| University of Missouri Health System | Columbia | Missouri | 65212 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Long Island Vitreoretinal Consultants - Westbury | Westbury | New York | 11590 | — |
| Verum Research, LLC | Eugene | Oregon | 97401 | — |
| Mid Atlantic Retina - Bethlehem | Bethlehem | Pennsylvania | 18017 | — |
| Charleston Neuroscience Institute - Charleston | Charleston | South Carolina | 29414 | — |
| Tennessee Retina | Nashville | Tennessee | 37203 | — |
| Austin Clinical Research, LLC | Austin | Texas | 78750 | — |
| Retina Consultants of Texas-Beaumont-70319 | Beaumont | Texas | 77707 | — |
| Retina Consultants of Texas-Bellaire-67493 | Bellaire | Texas | 77401 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | — |
| Retina Consultants of Texas - Katy | Katy | Texas | 77494 | — |
| Red River Research Partners, LLC | Plano | Texas | 75024 | — |
| Retinal Consultants of San Antonio | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas - Schertz | Schertz | Texas | 78154 | — |
| Retina Consultants of Texas-The Woodlands-67575 | The Woodlands | Texas | 77384 | — |
| Retina Associates of Utah | Salt Lake City | Utah | 84107 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Spokane Eye Clinic | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06722157, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 14, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06722157 live on ClinicalTrials.gov.