Study to Evaluate Safety and Immunogenicity of a Pandemic Flu H5 mRNA Vaccine in Healthy Adults Aged 18 Years and Older
Public ClinicalTrials.gov record NCT06727058. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Randomized, Modified Double-blind, Placebo-controlled, Multi-center, Dose Escalating Study to Evaluate the Safety and Immunogenicity of a Pandemic Flu H5 mRNA Vaccine in Healthy Adults Aged 18 Years and Older
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate a pandemic flu H5 strain messenger ribonucleic acid (mRNA) vaccine at 3 dose levels (low, medium, and high) in comparison with placebo in 276 healthy adult participants to select the adequate dose for further clinical development. The duration per participant will be approximately 13 months.
Study identification
- NCT ID
- NCT06727058
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 276 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 8, 2024
- Primary completion
- Mar 23, 2026
- Completion
- Mar 23, 2026
- Last update posted
- Apr 22, 2026
2024 – 2026
United States locations
- U.S. sites
- 14
- U.S. states
- 10
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Velocity Clinical Research - San Diego- Site Number : 8400013 | La Mesa | California | 91942 | — |
| Accel Research Sites Network - DeLand Clinical Research Unit- Site Number : 8400002 | DeLand | Florida | 32720 | — |
| ARSN-Lakeland CRU- Site Number : 8400006 | Lakeland | Florida | 33803 | — |
| Accel Research Sites - St. Petersburg- Site Number : 8400004 | Largo | Florida | 33777 | — |
| Atlanta Clinical Research Center- Site Number : 8400007 | Atlanta | Georgia | 30342 | — |
| Accel Research Site - NeuroStudies.net, LLC - ERN - PPDS- Site Number : 8400003 | Decatur | Georgia | 30030-2627 | — |
| QUEST Research Institute- Site Number : 8400014 | Bingham Farms | Michigan | 48334 | — |
| Velocity Clinical Research - Norfolk- Site Number : 8400015 | Norfolk | Nebraska | 68701 | — |
| Velocity Clinical Research - Omaha- Site Number : 8400012 | Omaha | Nebraska | 68134 | — |
| Velocity Clinical Research - Springdale- Site Number : 8400010 | Cincinnati | Ohio | 45246 | — |
| Coastal Carolina Research Center - North Charleston- Site Number : 8400001 | North Charleston | South Carolina | 29405 | — |
| Olympus Clinical Research - Sugar Land- Site Number : 8400009 | Sugar Land | Texas | 77479 | — |
| Velocity Clinical Research, Salt Lake City- Site Number : 8400011 | West Jordan | Utah | 84088 | — |
| Charlottesville Medical Research- Site Number : 8400005 | Charlottesville | Virginia | 22911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06727058, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06727058 live on ClinicalTrials.gov.