ClinicalTrials.gov record
Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung Cancer
ClinicalTrials.gov ID: NCT06732401
Public ClinicalTrials.gov record NCT06732401. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 10, 2026, 4:11 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase III Trial of Checkpoint Blockade in Lung Cancer Patients in the Adjuvant Setting Based on Pathologic Response Following Neoadjuvant Therapy (CLEAR)
Study identification
- NCT ID
- NCT06732401
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 630 participants
Conditions and interventions
Conditions
Interventions
- Biospecimen Collection Procedure
- Ceralasertib Drug
- Computed Tomography Procedure
- Durvalumab Biological
- Echocardiography Test Procedure
Procedure · Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 6, 2025
- Primary completion
- Jun 29, 2028
- Completion
- Jun 29, 2028
- Last update posted
- May 3, 2026
2025 – 2028
United States locations
- U.S. sites
- 193
- U.S. states
- 31
- U.S. cities
- 167
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro | Arkansas | 72401 | — |
| Tower Cancer Research Foundation | Beverly Hills | California | 90211 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Cedars-Sinai Cancer - Tarzana | Tarzana | California | 91356 | — |
| Torrance Memorial Physician Network - Cancer Care | Torrance | California | 90505 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Midstate Medical Center | Meriden | Connecticut | 06451 | — |
| The Hospital of Central Connecticut | New Britain | Connecticut | 06050 | — |
| Beebe South Coastal Health Campus | Millville | Delaware | 19967 | — |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | — |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Emory Decatur Hospital | Decatur | Georgia | 30033 | — |
| Emory Johns Creek Hospital | Johns Creek | Georgia | 30097 | — |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | — |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | — |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | — |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | — |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | — |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83687 | — |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | — |
| Kootenai Clinic Cancer Services - Sandpoint | Sandpoint | Idaho | 83864 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Northwestern Medicine Cancer Center Kishwaukee | DeKalb | Illinois | 60115 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Illinois CancerCare-Dixon | Dixon | Illinois | 61021 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | — |
| Northwestern Medicine Glenview Outpatient Center | Glenview | Illinois | 60026 | — |
| Northwestern Medicine Grayslake Outpatient Center | Grayslake | Illinois | 60030 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois | 60045 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| HSHS Saint Elizabeth's Hospital | O'Fallon | Illinois | 62269 | — |
| Northwestern Medicine Oak Brook | Oak Brook | Illinois | 60523 | — |
| Northwestern Medicine Orland Park | Orland Park | Illinois | 60462 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | — |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Cancer Center of Kansas - El Dorado | El Dorado | Kansas | 67042 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Cancer Center of Kansas - Newton | Newton | Kansas | 67114 | — |
| The University of Kansas Cancer Center - Olathe | Olathe | Kansas | 66061 | — |
| Salina Regional Health Center | Salina | Kansas | 67401 | — |
| University of Kansas Health System Saint Francis Campus | Topeka | Kansas | 66606 | — |
| Cancer Center of Kansas - Wellington | Wellington | Kansas | 67152 | — |
| Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Ascension Via Christi Hospitals Wichita | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Wichita | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Winfield | Winfield | Kansas | 67156 | — |
| University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| UM Baltimore Washington Medical Center/Tate Cancer Center | Glen Burnie | Maryland | 21061 | — |
| Beverly Hospital | Beverly | Massachusetts | 01915 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Addison Gilbert Hospital | Gloucester | Massachusetts | 01930 | — |
| Lahey Medical Center-Peabody | Peabody | Massachusetts | 01960 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | 48118 | — |
| Cancer Hematology Centers - Flint | Flint | Michigan | 48503 | — |
| Genesee Hematology Oncology PC | Flint | Michigan | 48503 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Grand Rapids | Michigan | 49503 | — |
| Trinity Health Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | — |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | — |
| Trinity Health Muskegon Hospital | Muskegon | Michigan | 49444 | — |
| Corewell Health Lakeland Hospitals - Niles Hospital | Niles | Michigan | 49120 | — |
| Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | 49444 | — |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | — |
| Corewell Health Reed City Hospital | Reed City | Michigan | 49677 | — |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital | Saint Joseph | Michigan | 49085 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| University of Michigan Health - West | Wyoming | Michigan | 49519 | — |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | — |
| Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | 56401 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health - Deer River Clinic | Deer River | Minnesota | 56636 | — |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Essentia Health Hibbing Clinic | Hibbing | Minnesota | 55746 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Minneapolis VA Medical Center | Minneapolis | Minnesota | 55417 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Essentia Health Sandstone | Sandstone | Minnesota | 55072 | — |
| Essentia Health Virginia Clinic | Virginia | Minnesota | 55792 | — |
| Baptist Memorial Hospital and Cancer Center-Golden Triangle | Columbus | Mississippi | 39705 | — |
| Baptist Cancer Center-Grenada | Grenada | Mississippi | 38901 | — |
| Baptist Memorial Hospital and Cancer Center-Union County | New Albany | Mississippi | 38652 | — |
| Baptist Memorial Hospital and Cancer Center-Oxford | Oxford | Mississippi | 38655 | — |
| Baptist Memorial Hospital and Cancer Center-Desoto | Southhaven | Mississippi | 38671 | — |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | — |
| Parkland Health Center - Farmington | Farmington | Missouri | 63640 | — |
| Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | 63670 | — |
| Mercy Hospital South | St Louis | Missouri | 63128 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Missouri Baptist Sullivan Hospital | Sullivan | Missouri | 63080 | — |
| BJC Outpatient Center at Sunset Hills | Sunset Hills | Missouri | 63127 | — |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | — |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | — |
| Saint Vincent Frontier Cancer Center | Billings | Montana | 59102 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Community Medical Center | Missoula | Montana | 59804 | — |
| New Hampshire Oncology Hematology PA-Concord | Concord | New Hampshire | 03301 | — |
| Solinsky Center for Cancer Care | Manchester | New Hampshire | 03103 | — |
| Hunterdon Medical Center | Flemington | New Jersey | 08822 | — |
| Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | — |
| FirstHealth of the Carolinas-Moore Regional Hospital | Pinehurst | North Carolina | 28374 | — |
| Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | 58103 | — |
| Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Providence Willamette Falls Medical Center | Oregon City | Oregon | 97045 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | — |
| Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | 18017 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | — |
| UPMC Hillman Cancer Center Erie | Erie | Pennsylvania | 16505 | — |
| UPMC Cancer Centers - Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| UPMC Pinnacle Cancer Center/Community Osteopathic Campus | Harrisburg | Pennsylvania | 17109 | — |
| Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania | 18201 | — |
| UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion | Mechanicsburg | Pennsylvania | 17050 | — |
| Riddle Memorial Hospital | Media | Pennsylvania | 19063 | — |
| UPMC Hillman Cancer Center - Monroeville | Monroeville | Pennsylvania | 15146 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC-Saint Clair Hospital Cancer Center | Pittsburgh | Pennsylvania | 15243 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Tidelands Georgetown Memorial Hospital | Georgetown | South Carolina | 29440 | — |
| Baptist Memorial Hospital and Cancer Center-Collierville | Collierville | Tennessee | 38017 | — |
| Baptist Memorial Hospital and Cancer Center-Memphis | Memphis | Tennessee | 38120 | — |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | — |
| Hematology Oncology Associates of Fredericksburg Inc | Fredericksburg | Virginia | 22408 | — |
| Virginia Cancer Institute | Richmond | Virginia | 23229 | — |
| VCU Massey Cancer Center at Stony Point | Richmond | Virginia | 23235 | — |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | — |
| VCU Community Memorial Health Center | South Hill | Virginia | 23970 | — |
| Edwards Comprehensive Cancer Center | Huntington | West Virginia | 25701 | — |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | — |
| Camden Clark Medical Center | Parkersburg | West Virginia | 26101 | — |
| Langlade Hospital and Cancer Center | Antigo | Wisconsin | 54409 | — |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | — |
| Duluth Clinic Ashland | Ashland | Wisconsin | 54806 | — |
| Essentia Health-Hayward Clinic | Hayward | Wisconsin | 54843 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| Aspirus Medford Hospital | Medford | Wisconsin | 54451 | — |
| ProHealth D N Greenwald Center | Mukwonago | Wisconsin | 53149 | — |
| ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | 53066 | — |
| Aspirus Cancer Care - James Beck Cancer Center | Rhinelander | Wisconsin | 54501 | — |
| Essentia Health-Spooner Clinic | Spooner | Wisconsin | 54801 | — |
| Aspirus Cancer Care - Stevens Point | Stevens Point | Wisconsin | 54481 | — |
| Essentia Health Saint Mary's Hospital - Superior | Superior | Wisconsin | 54880 | — |
| UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | 53188 | — |
| Aspirus Regional Cancer Center | Wausau | Wisconsin | 54401 | — |
| Aspirus Cancer Care - Wisconsin Rapids | Wisconsin Rapids | Wisconsin | 54494 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06732401, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2026 · Synced May 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06732401 live on ClinicalTrials.gov.