A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
Public ClinicalTrials.gov record NCT06740630. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3a, Observer-blind, Randomized, Controlled Study to Demonstrate Lot-to-lot Consistency and Evaluate the Immunogenicity and Safety of an Investigational Varicella Vaccine Compared With Varivax, Administered as a First Dose to Healthy Children 12 to 15 Months of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the consistency of immune response to three different lots of GSK's investigational varicella vaccine (VNS Vaccine), and to compare the safety and immune response of VNS vaccine to an already approved varicella vaccine (VV) known as Varivax. The study will be conducted in healthy children aged 12 to 15 months, who have neither contracted varicella nor received a varicella vaccination.
Study identification
- NCT ID
- NCT06740630
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,840 participants
Conditions and interventions
Conditions
Interventions
- Investigational varicella vaccine_Lot 1 Biological
- Investigational varicella vaccine_Lot 2 Biological
- Investigational varicella vaccine_Lot 3 Biological
- Marketed varicella vaccine_Lot 1 Biological
- Marketed varicella vaccine_Lot 2 Biological
- MMR vaccine Biological
- Hepatitis A vaccine Biological
- PCV (pneumococcal conjugate vaccine) 13 Biological
- PCV 20 Biological
- Vaxneuvance Biological
Biological
Eligibility (public fields only)
- Age range
- 12 Months to 15 Months
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2025
- Primary completion
- Dec 24, 2026
- Completion
- May 16, 2027
- Last update posted
- May 28, 2026
2025 – 2027
United States locations
- U.S. sites
- 59
- U.S. states
- 24
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Mobile | Alabama | 36608 | Recruiting |
| GSK Investigational Site | Hot Springs | Arkansas | 71913 | Recruiting |
| GSK Investigational Site | Sherwood | Arkansas | 72120 | Recruiting |
| GSK Investigational Site | Canoga Park | California | 91304 | Recruiting |
| GSK Investigational Site | Covina | California | 91723 | Recruiting |
| GSK Investigational Site | Fullerton | California | 92835 | Withdrawn |
| GSK Investigational Site | Long Beach | California | 90807 | Withdrawn |
| GSK Investigational Site | Los Angeles | California | 90057 | Recruiting |
| GSK Investigational Site | Paramount | California | 90723 | Withdrawn |
| GSK Investigational Site | Sacramento | California | 95823 | Recruiting |
| GSK Investigational Site | Ventura | California | 93003 | Recruiting |
| GSK Investigational Site | Walnut Creek | California | 94598 | Recruiting |
| GSK Investigational Site | Winnetka | California | 91306 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33176 | Withdrawn |
| GSK Investigational Site | Miami | Florida | 33184 | Recruiting |
| GSK Investigational Site | Miami Lakes | Florida | 33014 | Recruiting |
| GSK Investigational Site | Spring Hill | Florida | 34609 | Recruiting |
| GSK Investigational Site | Tampa | Florida | 33613 | Recruiting |
| GSK Investigational Site | Covington | Georgia | 70433 | Recruiting |
| GSK Investigational Site | Ammon | Idaho | 83406 | Recruiting |
| GSK Investigational Site | Moline | Illinois | 61265 | Recruiting |
| GSK Investigational Site | South Bend | Indiana | 46617 | Recruiting |
| GSK Investigational Site | Topeka | Kansas | 66606 | Recruiting |
| GSK Investigational Site | Bardstown | Kentucky | 40004 | Recruiting |
| GSK Investigational Site | Louisville | Kentucky | 40202-1822 | Recruiting |
| GSK Investigational Site | Haughton | Louisiana | 71037 | Recruiting |
| GSK Investigational Site | Fall River | Massachusetts | 02721-1735 | Recruiting |
| GSK Investigational Site | Bingham Farms | Michigan | 48025 | Recruiting |
| GSK Investigational Site | Jefferson City | Missouri | 65109 | Recruiting |
| GSK Investigational Site | Lincoln | Nebraska | 68505 | Recruiting |
| GSK Investigational Site | Lincoln | Nebraska | 68510 | Withdrawn |
| GSK Investigational Site | Lincoln | Nebraska | 68516 | Recruiting |
| GSK Investigational Site | The Bronx | New York | 10456 | Recruiting |
| GSK Investigational Site | Charlotte | North Carolina | 28203 | Recruiting |
| GSK Investigational Site | Monroe | North Carolina | 28112 | Withdrawn |
| GSK Investigational Site | Cleveland | Ohio | 44121 | Recruiting |
| GSK Investigational Site | Dayton | Ohio | 45424 | Recruiting |
| GSK Investigational Site | Chickasha | Oklahoma | 73018 | Recruiting |
| GSK Investigational Site | Tulsa | Oklahoma | 74137 | Recruiting |
| GSK Investigational Site | Gresham | Oregon | 97030 | Recruiting |
| GSK Investigational Site | Charleston | South Carolina | 29407 | Recruiting |
| GSK Investigational Site | Charleston | South Carolina | 29414 | Recruiting |
| GSK Investigational Site | Greenville | South Carolina | 29607 | Recruiting |
| GSK Investigational Site | Simpsonville | South Carolina | 29681 | Recruiting |
| GSK Investigational Site | Beaumont | Texas | 77701 | Recruiting |
| GSK Investigational Site | Burleson | Texas | 76028 | Withdrawn |
| GSK Investigational Site | Corpus Christi | Texas | 78404 | Recruiting |
| GSK Investigational Site | Dallas | Texas | 75230-2571 | Recruiting |
| GSK Investigational Site | Dallas | Texas | 75251 | Withdrawn |
| GSK Investigational Site | Houston | Texas | 77030 | Recruiting |
| GSK Investigational Site | Houston | Texas | 77087 | Recruiting |
| GSK Investigational Site | McAllen | Texas | 78504 | Recruiting |
| GSK Investigational Site | Mesquite | Texas | 75149 | Recruiting |
| GSK Investigational Site | Layton | Utah | 84041 | Completed |
| GSK Investigational Site | Murray | Utah | 84107 | Recruiting |
| GSK Investigational Site | Pleasant View | Utah | 84404 | Recruiting |
| GSK Investigational Site | South Jordan | Utah | 84095 | Recruiting |
| GSK Investigational Site | West Jordan | Utah | 84088 | Withdrawn |
| GSK Investigational Site | Richmond | Virginia | 23226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06740630, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 28, 2026 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06740630 live on ClinicalTrials.gov.