A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy
Public ClinicalTrials.gov record NCT06742190. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Empasiprubart Versus Intravenous Immunoglobulin in Adults With Multifocal Motor Neuropathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to compare empasiprubart and IVIg in adult patients with MMN. The study consists of a double-blinded part A (empasiprubart, IVIg) and an open-label part B (empasiprubart). The maximum study duration for participants is up to 49 months. More information can be found here: https://clinicaltrials.argenx.com/empassion
Study identification
- NCT ID
- NCT06742190
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 154 participants
Conditions and interventions
Conditions
Interventions
- Empasiprubart Biological
- IVIG (Intravenous Immunoglobulin) Biological
- Empasiprubart-placebo Other
- IVIg-placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 18, 2024 (Actual)
- Primary completion
- Sep 2026 (Estimated)
- Completion
- Dec 2029 (Estimated)
- Last update posted
- Sep 22, 2026
2024 – 2029
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HonorHealth Neurology - Bob Bove Neuroscience Institute - Neurology | Scottsdale | Arizona | 85251 | — |
| The Neurology Group | Pomona | California | 91767 | — |
| Samir Macwan, M.D., Inc. | Rancho Mirage | California | 92270 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| University of Colorado - Anschutz Cancer Pavilion (Neuro Onc Clinic) | Aurora | Colorado | 80045 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06511 | — |
| Medstar Health Research Institute | Washington D.C. | District of Columbia | 20010 | — |
| EZR Research LLC | Boca Raton | Florida | 33486 | — |
| Healthcare Innovations Institute, LLC | Coral Springs | Florida | 33067 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Indiana University Health Neuroscience Center | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Fairway | Kansas | 66205 | — |
| Perelman Center for Advanced Medicine | Columbia | Maryland | 21044 | — |
| UC Irvine - MDA ALS and Neuromuscular Center | Columbia | Maryland | 21044 | — |
| University of Minnesota | Minneapolis | Minnesota | 55414 | — |
| Dent Neurologic Institute Amherst | Amherst | New York | 14226 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| University of North Carolina at Chapel Hill | Morrisville | North Carolina | 27560 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| National Neuromuscular Research Institute | Austin | Texas | 78759-8402 | — |
| NeuroCarePlus | Houston | Texas | 77094 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 85 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06742190, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 22, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06742190 live on ClinicalTrials.gov.