A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

ClinicalTrials.gov ID: NCT06742723

Public ClinicalTrials.gov record NCT06742723. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 2:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomised, Double-blind, Placebo-controlled, Event-driven Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on Renal Outcomes and Cardiovascular Mortality in Participants With Chronic Kidney Disease and High Blood Pressure

Study identification

NCT ID: NCT06742723
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AstraZeneca; Industry
Enrollment: 5,000 participants

Conditions and interventions

Conditions

Chronic Kidney Disease and Hypertension

Interventions

Baxdrostat/dapagliflozin Drug
Placebo/dapagliflozin Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 2, 2025
Primary completion: Dec 17, 2029
Completion: Dec 17, 2029
Last update posted: Apr 29, 2026

2025 – 2029

United States locations

U.S. sites: 130
U.S. states: 33
U.S. cities: 116

Facility	City	State	ZIP	Site status
Research Site	Fairhope	Alabama	36532	Recruiting
Research Site	Surprise	Arizona	85374	Recruiting
Research Site	Tucson	Arizona	85710	Recruiting
Research Site	Beverly Hills	California	90211	Recruiting
Research Site	Canoga Park	California	91303	Withdrawn
Research Site	Concord	California	94520	Recruiting
Research Site	Fremont	California	94538	Recruiting
Research Site	Fullerton	California	92835	Recruiting
Research Site	Inglewood	California	90301	Withdrawn
Research Site	Los Alamitos	California	90720	Recruiting
Research Site	Los Angeles	California	90073	Recruiting
Research Site	San Diego	California	92120	Withdrawn
Research Site	San Francisco	California	94110	Withdrawn
Research Site	Stanford	California	94305	Not yet recruiting
Research Site	Tarzana	California	91356	Recruiting
Research Site	Arvada	Colorado	80002	Recruiting
Research Site	Denver	Colorado	80220	Withdrawn
Research Site	New Britain	Connecticut	06051	Recruiting
Research Site	Washington D.C.	District of Columbia	20037	Recruiting
Research Site	Boca Raton	Florida	33487	Recruiting
Research Site	Boynton Beach	Florida	33435	Recruiting
Research Site	Edgewater	Florida	32132	Recruiting
Research Site	Fort Lauderdale	Florida	33316	Recruiting
Research Site	Hollywood	Florida	33021	Recruiting
Research Site	Jacksonville Beach	Florida	32250	Recruiting
Research Site	Lake City	Florida	32055	Recruiting
Research Site	Lakeland	Florida	33805	Recruiting
Research Site	Melbourne	Florida	32901	Recruiting
Research Site	Miami Lakes	Florida	33014	Suspended
Research Site	Ocoee	Florida	34761	Recruiting
Research Site	Port Charlotte	Florida	33952	Recruiting
Research Site	Port Orange	Florida	32127	Recruiting
Research Site	Riverview	Florida	33578	Recruiting
Research Site	Atlanta	Georgia	30328	Recruiting
Research Site	Atlanta	Georgia	30344	Recruiting
Research Site	Augusta	Georgia	30904	Withdrawn
Research Site	Austell	Georgia	30106	Suspended
Research Site	Brunswick	Georgia	31520	Recruiting
Research Site	Conyers	Georgia	30094	Recruiting
Research Site	Decatur	Georgia	30030	Recruiting
Research Site	Lawrenceville	Georgia	30046	Recruiting
Research Site	Riverdale	Georgia	30274	Recruiting
Research Site	Honolulu	Hawaii	96814	Suspended
Research Site	Champaign	Illinois	61822	Recruiting
Research Site	Maywood	Illinois	60153	Recruiting
Research Site	Rockford	Illinois	61107	Recruiting
Research Site	Evansville	Indiana	47714	Withdrawn
Research Site	Indianapolis	Indiana	46202	Recruiting
Research Site	Iowa City	Iowa	52242	Recruiting
Research Site	West Des Moines	Iowa	50266	Recruiting
Research Site	Hutchinson	Kansas	67502	Recruiting
Research Site	Kansas City	Kansas	66112	Recruiting
Research Site	Wichita	Kansas	67214	Recruiting
Research Site	Kenner	Louisiana	70065	Withdrawn
Research Site	Metairie	Louisiana	70006	Recruiting
Research Site	West Monroe	Louisiana	71291	Recruiting
Research Site	Bethesda	Maryland	20889	Recruiting
Research Site	Boston	Massachusetts	02114	Withdrawn
Research Site	Boston	Massachusetts	02115	Recruiting
Research Site	Braintree	Massachusetts	02184	Not yet recruiting
Research Site	New Bedford	Massachusetts	02740	Recruiting
Research Site	Worcester	Massachusetts	01608	Recruiting
Research Site	Ann Arbor	Michigan	48109	Recruiting
Research Site	Detroit	Michigan	48202	Recruiting
Research Site	Garden City	Michigan	48135	Recruiting
Research Site	Saint Joseph	Michigan	49085	Recruiting
Research Site	Kansas City	Missouri	64111	Recruiting
Research Site	Kansas City	Missouri	64151	Recruiting
Research Site	St Louis	Missouri	63136	Recruiting
Research Site	Norfolk	Nebraska	68701	Recruiting
Research Site	Las Vegas	Nevada	89109	Withdrawn
Research Site	Eatontown	New Jersey	07724	Recruiting
Research Site	Albany	New York	12205	Recruiting
Research Site	Buffalo	New York	14203	Recruiting
Research Site	New York	New York	10016	Recruiting
Research Site	Greenville	North Carolina	27834	Recruiting
Research Site	Hickory	North Carolina	28601	Recruiting
Research Site	Jacksonville	North Carolina	28546	Recruiting
Research Site	Kinston	North Carolina	28504	Recruiting
Research Site	Morehead City	North Carolina	28557	Recruiting
Research Site	New Bern	North Carolina	28562	Recruiting
Research Site	Raleigh	North Carolina	27609	Recruiting
Research Site	Rocky Mount	North Carolina	27804	Recruiting
Research Site	Sanford	North Carolina	27330	Recruiting
Research Site	Statesville	North Carolina	28625	Recruiting
Research Site	Wilmington	North Carolina	28401	Recruiting
Research Site	Wilmington	North Carolina	28412	Recruiting
Research Site	Winston-Salem	North Carolina	27103	Recruiting
Research Site	Canton	Ohio	44718	Recruiting
Research Site	Cincinnati	Ohio	45212	Recruiting
Research Site	Cincinnati	Ohio	45219	Recruiting
Research Site	Columbus	Ohio	43210	Recruiting
Research Site	Columbus	Ohio	43213	Recruiting
Research Site	Columbus	Ohio	43215	Recruiting
Research Site	Bridgeville	Pennsylvania	15017	Recruiting
Research Site	Butler	Pennsylvania	16001	Recruiting
Research Site	Exton	Pennsylvania	19341	Recruiting
Research Site	Media	Pennsylvania	19063	Recruiting
Research Site	East Providence	Rhode Island	02914	Recruiting
Research Site	East Providence	Rhode Island	02915	Recruiting
Research Site	Providence	Rhode Island	02904	Suspended
Research Site	Charleston	South Carolina	29414	Recruiting
Research Site	Columbia	South Carolina	29203	Recruiting
Research Site	Orangeburg	South Carolina	29118	Not yet recruiting
Research Site	Chattanooga	Tennessee	37421	Recruiting
Research Site	Knoxville	Tennessee	37912	Recruiting
Research Site	Knoxville	Tennessee	37938	Recruiting
Research Site	Nashville	Tennessee	37232	Recruiting
Research Site	Arlington	Texas	76015	Recruiting
Research Site	Austin	Texas	78726	Recruiting
Research Site	Austin	Texas	78735	Recruiting
Research Site	Austin	Texas	78751	Recruiting
Research Site	Dallas	Texas	75230	Withdrawn
Research Site	Dallas	Texas	75234	Recruiting
Research Site	Dallas	Texas	75246	Recruiting
Research Site	Houston	Texas	77004	Recruiting
Research Site	Houston	Texas	77099	Recruiting
Research Site	Humble	Texas	77346	Recruiting
Research Site	Lewisville	Texas	75057	Suspended
Research Site	Pasadena	Texas	77504	Recruiting
Research Site	Pearland	Texas	77584	Suspended
Research Site	San Antonio	Texas	78212	Recruiting
Research Site	South Salt Lake	Utah	84115	Recruiting
Research Site	Burlington	Vermont	05401	Recruiting
Research Site	Arlington	Virginia	22205	Recruiting
Research Site	Manassas	Virginia	20110	Recruiting
Research Site	Newport News	Virginia	23606	Recruiting
Research Site	Richmond	Virginia	23249	Not yet recruiting
Research Site	Woodbridge	Virginia	22192	Recruiting
Research Site	Seattle	Washington	98195	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 614 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06742723, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 29, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06742723 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →