A Study to Evaluate the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT06754462. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Multicenter, Double-blind, Placebo-controlled Randomized Withdrawal Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Participants With Active, Difficult to Treat, ACPA-Positive Rheumatoid Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 2b, multicenter, double-blind, placebo-controlled, randomized withdrawal study is designed to assess the efficacy and safety of IMVT-1402 in adult participants with active, difficult-to-treat, anti-citrullinated protein autoantibody (ACPA) positive rheumatoid arthritis (RA).
Study identification
- NCT ID
- NCT06754462
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 120 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 10, 2025 (Actual)
- Primary completion
- Sep 2027 (Estimated)
- Completion
- Sep 2027 (Estimated)
- Last update posted
- Apr 22, 2026
2025 – 2027
United States locations
- U.S. sites
- 34
- U.S. states
- 15
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site Number - 1018 | Mesa | Arizona | 85210 | — |
| Site Number - 1019 | Sun City | Arizona | 85351 | — |
| Site Number - 1022 | Covina | California | 91722 | — |
| Site Number - 1028 | San Leandro | California | 94578 | — |
| Site Number - 1024 | Temecula | California | 92592 | — |
| Site Number - 1033 | Tujunga | California | 91042 | — |
| Site Number - 1023 | Whittier | California | 90602 | — |
| Site Number - 1020 | Denver | Colorado | 80230 | — |
| Site Number - 1015 | Jupiter | Florida | 33458 | — |
| Site Number - 1002 | Miami | Florida | 33143 | — |
| Site Number - 1027 | Plantation | Florida | 33324 | — |
| Site Number - 1005 | Winter Park | Florida | 32789 | — |
| Site Number - 1012 | Zephyrhills | Florida | 33542 | — |
| Site Number - 1001 | Gainesville | Georgia | 30501 | — |
| Site Number - 1034 | Chicago | Illinois | 60607 | — |
| Site Number - 1006 | Cumberland | Maryland | 21502 | — |
| Site Number - 1007 | Hagerstown | Maryland | 21740 | — |
| Site Number - 1031 | Rockville | Maryland | 20850 | — |
| Site Number - 1008 | Worcester | Massachusetts | 01605 | — |
| Site Number - 1021 | Saint Clair Shores | Michigan | 48081 | — |
| Site Number - 1030 | Kansas City | Missouri | 64151 | — |
| Site Number - 1010 | Summit | New Jersey | 07901 | — |
| Site Number - 1004 | Charlotte | North Carolina | 28207 | — |
| Site Number - 1035 | Statesville | North Carolina | 28625 | — |
| Site Number - 1000 | Duncansville | Pennsylvania | 16635 | — |
| Site Number - 1016 | Jackson | Tennessee | 38305 | — |
| Site Number - 1026 | Memphis | Tennessee | 38119 | — |
| Site Number - 1029 | Murfreesboro | Tennessee | 37128 | — |
| Site Number - 1037 | Allen | Texas | 75013 | — |
| Site Number - 1017 | Colleyville | Texas | 76034 | — |
| Site Number - 1036 | Katy | Texas | 77494 | — |
| Site Number - 1014 | Mesquite | Texas | 75150 | — |
| Site Number - 1013 | Tomball | Texas | 77375 | — |
| Site Number - 1025 | Tomball | Texas | 77377 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 49 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06754462, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06754462 live on ClinicalTrials.gov.