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Completed Phase 1 Interventional

A Study to Investigate RO7200220 as Monotherapy and in Combination With Ranibizumab in Participants With Diabetic and Uveitic Macular Edema

ClinicalTrials.gov ID: NCT06771271

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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT06771271. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 12, 2026, 10:02 AM EST

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Official title

A Multi-center, Non-Randomized, Open-label, Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7200220 in Monotherapy and in Combination With Ranibizumab Following Intravitreal Administration in Patients With Diabetic or Uveitic Macular Edema

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study was to assess the safety and tolerability of RO7200220 as monotherapy (diabetic macular edema \[DME\] or uveitic macular edema \[UME\] population) and in combination with ranibizumab (DME population only).

Study identification

NCT ID
NCT06771271
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
85 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 22, 2019 (Actual)
Primary completion
Nov 13, 2023 (Actual)
Completion
Nov 13, 2023 (Actual)
Last update posted
Jan 13, 2025

2019 – 2023

United States locations

U.S. sites
19
U.S. states
12
U.S. cities
19
Facility City State ZIP Site status
Retina-Vitreous Associates Medical Group Beverly Hills California 90211 —
California Retina Consultants Oxnard California 93036 —
Retina Institute of California Medical Group d/b/a Acuity Eye Group Palm Desert California 92260 —
Byers Eye Insitute at Stanford Palo Alto California 94303 —
Florida Eye Associates Melbourne Florida 32901 —
Retina Vitreous Assoc of FL St. Petersburg Florida 33711 —
Illinois Retina Associates SC Oak Park Illinois 60304 —
Cumberland Valley Retina PC Hagerstown Maryland 21740 —
Sierra Eye Associates Reno Nevada 89502 —
Wake Forest Baptist Medical Center Winston-Salem North Carolina 27157 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
Oregon HSU Portland Oregon 97239 —
Mid Atlantic Retina Philadelphia Pennsylvania 19107 —
Retina Res Institute of Texas Abilene Texas 79606 —
Austin Clinical Research LLC Austin Texas 78750 —
Valley Retina Institute P.A. McAllen Texas 78503 —
Medical Center Ophthalmology Associates San Antonio Texas 78240 —
Univ of Virginia Ophthalmology Charlottesville Virginia 22903 —
Karalis Johnson Retina Center Seattle Washington 98109 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06771271, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 13, 2025 · Synced Nov 12, 2026

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