A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hypertension
Public ClinicalTrials.gov record NCT06785454. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double Blind, Placebo Controlled, Crossover Study to Evaluate the Efficacy and Safety of Lorundrostat in Participants With Moderate to Severe Obstructive Sleep Apnea and Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of the study is to assess the effect of lorundrostat taken orally (po) once a day on the Apnea-Hypopnea Index (AHI) in participants with moderate to severe obstructive sleep apnea (OSA) and hypertension.
Study identification
- NCT ID
- NCT06785454
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 48 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2025 (Actual)
- Primary completion
- Dec 17, 2025 (Actual)
- Completion
- Dec 29, 2025 (Actual)
- Last update posted
- Aug 21, 2026
2025
United States locations
- U.S. sites
- 27
- U.S. states
- 17
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama | Tuscaloosa | Alabama | 35401 | — |
| Chandler Clinical Trials | Chandler | Arizona | 85224 | — |
| Preferred Research Partners Inc. | Little Rock | Arkansas | 72211 | — |
| Orange County Research Institute | Anaheim | California | 92801 | — |
| The Neurology Center of Southern California - Profound Research, LLC | Carlsbad | California | 92011 | — |
| Probe Clinical Research Corporation | Riverside | California | 92501 | — |
| Research Carolina Elite | Denver | Colorado | 28037 | — |
| Nouvelle Clinical Research | Cutler Bay | Florida | 33189 | — |
| Arrow Clinical Trials | Daytona Beach | Florida | 32117 | — |
| PharmaDev Clinical Research Institute, LLC | Miami | Florida | 33176 | — |
| CNS Healthcare - Orlando (Clinical Neuroscience Solutions) | Orlando | Florida | 32801 | — |
| NeuroTrials Research Inc | Atlanta | Georgia | 30328 | — |
| Centricity Research Rincon Pulmonology | Rincon | Georgia | 31326 | — |
| Chicago Research Center Inc | Chicago | Illinois | 60634 | — |
| Centennial Medical Group | Columbia | Maryland | 21045 | — |
| Velocity Clinical Research, Rockville | Rockville | Maryland | 20854 | — |
| Henry Ford Health System/Henry Ford Medical Center - Columbus | Novi | Michigan | 48377 | — |
| Revive Research Institute, Inc | Southfield | Michigan | 48075 | — |
| Healthcare Research Network | Hazelwood | Missouri | 63042 | — |
| Clayton Sleep Institute | St Louis | Missouri | 63123 | — |
| Patient First MD | Middletown | New Jersey | 07748 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Northwest Research Center | Portland | Oregon | 97202 | — |
| CNS Healthcare - Memphis (Clinical Neuroscience Solutions - Memphis) | Memphis | Tennessee | 38119 | — |
| Huntsville Research Institute LLC | Huntsville | Texas | 77340 | — |
| Sleep Therapy Research Center | San Antonio | Texas | 78229 | — |
| University of Washington | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06785454, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 21, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06785454 live on ClinicalTrials.gov.