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Recruiting Phase 1Phase 2 Interventional

A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)

ClinicalTrials.gov ID: NCT06818643

Public ClinicalTrials.gov record NCT06818643. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 10:11 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Open-label Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Researchers are looking for new ways to treat people with certain advanced solid tumors. Advanced means the cancer has spread to other parts of the body and cannot be removed with surgery. Solid tumors are cancers mostly in body organs and tissues, not in the blood or other body liquids. The main goal of this study is to learn about the safety of MK-3120 and if people tolerate it.

Study identification

NCT ID
NCT06818643
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
270 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 24, 2025
Primary completion
Oct 24, 2028
Completion
Mar 24, 2031
Last update posted
Jul 26, 2026

2025 – 2031

United States locations

U.S. sites
7
U.S. states
5
U.S. cities
7
Facility City State ZIP Site status
The University of Alabama at Birmingham ( Site 1005) Birmingham Alabama 35249 Recruiting
University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 1003) Miami Florida 33136 Recruiting
John Theurer Cancer Center at Hackensack University Medical Center ( Site 1009) Hackensack New Jersey 07601 Recruiting
NEXT Oncology ( Site 1010) Austin Texas 78758 Recruiting
NEXT Oncology ( Site 1011) Houston Texas 77054 Recruiting
NEXT Oncology ( Site 1012) Irving Texas 75039 Recruiting
Virginia Commonwealth University ( Site 1008) Richmond Virginia 23219 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06818643, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 26, 2026 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06818643 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →