A Phase 1b Study of the NLRP3 Inhibitor VENT-02 in Patients With Mild to Moderate Parkinson's Disease
Public ClinicalTrials.gov record NCT06822517. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Phase 1b Study of the NLRP3 Inhibitor VENT-02 in Patients With Mild to Moderate Parkinson's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial is a randomized, double-blind, placebo-controlled Phase 1b study evaluating the safety/tolerability, PK, and pharmacodynamics of VENT 02, administered orally at 1 dose level twice daily (BID) over 28 days in patients with mild to moderate Parkinson's disease. The study includes a screening period, a 28-day double-blind treatment period, and a 7-day follow-up period after last dose. Approximately 30 patients will be randomized into 1 of the 2 treatment arms.
Study identification
- NCT ID
- NCT06822517
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 29 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 45 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 5, 2025 (Actual)
- Primary completion
- Oct 9, 2025 (Actual)
- Completion
- Oct 9, 2025 (Actual)
- Last update posted
- Oct 29, 2025
2025
United States locations
- U.S. sites
- 23
- U.S. states
- 9
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigative Site | Fountain Valley | California | 92708 | — |
| Investigative Site | San Jose | California | 95124 | — |
| Investigative Site | West Hills | California | 91307 | — |
| Investigative Site | Englewood | Colorado | 80113 | — |
| Investigative Site | Aventura | Florida | 33180 | — |
| Investigative Site | Boca Raton | Florida | 33486 | — |
| Investigative Site | Coral Gables | Florida | 33134 | — |
| Investigative Site | Coral Springs | Florida | 33067 | — |
| Investigative Site | Cutler Bay | Florida | 33189 | — |
| Investigative Site | Daytona Beach | Florida | 32117 | — |
| Investigative Site | Doral | Florida | 33178 | — |
| Investigative Site | Jacksonville | Florida | 32256 | — |
| Investigative Site | Maitland | Florida | 32751 | — |
| Investigative Site | Miami | Florida | 33135 | — |
| Investigative Site | Miami | Florida | 33165 | — |
| Investigative Site | Winter Park | Florida | 32789 | — |
| Investigative Site | Scarborough | Maine | 04074 | — |
| Investigative Site | Farmington Hills | Michigan | 48334 | — |
| Investigative Site | Abington | Pennsylvania | 19001 | — |
| Investigative Site | Memphis | Tennessee | 38157 | — |
| Investigative Site | Cypress | Texas | 77429 | — |
| Investigative Site | Round Rock | Texas | 78681 | — |
| Investigative Site | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06822517, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2025 · Synced Oct 9, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06822517 live on ClinicalTrials.gov.