A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa
Public ClinicalTrials.gov record NCT06840392. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Double-dummy, Placebo-controlled, Multicenter, Phase 3 Study Assessing the Efficacy, Safety, and Tolerability of 2 Doses of Remibrutinib Over a 68-week Treatment Period in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to establish the efficacy, safety, and tolerability of remibrutinib (LOU064) Dose A and Dose B compared to placebo in participants with moderate to severe hidradenitis suppurativa (HS).
Study identification
- NCT ID
- NCT06840392
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 565 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 20, 2025 (Actual)
- Primary completion
- Jun 3, 2027 (Estimated)
- Completion
- Oct 21, 2027 (Estimated)
- Last update posted
- Oct 15, 2026
2025 – 2027
United States locations
- U.S. sites
- 35
- U.S. states
- 18
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Total Skin and Beauty Dermatology Center PC | Birmingham | Alabama | 35205 | — |
| CTT Research | Gilbert | Arizona | 85234 | — |
| Ctr for Dermatology Clinical Res | Fremont | California | 95438 | — |
| USC Keck School of Medicine | Los Angeles | California | 90033 | — |
| MedDerm Associates | San Diego | California | 92103 | — |
| Driven Research | Miami | Florida | 33126 | — |
| Floridian Research Institute | Miami | Florida | 33179 | — |
| Sarasota Arthritis Res Ctr | Sarasota | Florida | 34239 | — |
| University Of South Florida | Tampa | Florida | 33612 | — |
| Emory School of Med Dermatology | Atlanta | Georgia | 30303 | — |
| Atlanta Biomedical Clin Res LLC | Atlanta | Georgia | 30331 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Endeavor Health | Glenview | Illinois | 60077 | — |
| Dundee Dermatology | West Dundee | Illinois | 60118 | — |
| Southern IN Clinical Trials | New Albany | Indiana | 47150 | — |
| Beth Israel Deaconess Med Center | Boston | Massachusetts | 02215 | — |
| Metro Boston Clinical Partners | Brighton | Massachusetts | 02135 | — |
| Clinical Research Inst of MI | Chesterfield | Michigan | 48047 | — |
| Deluxe Dermatology | St Louis | Missouri | 63117 | — |
| Skin Specialists PC | Omaha | Nebraska | 68144 | — |
| Vivida Dermatology | Las Vegas | Nevada | 89119 | — |
| North Shore University Hospital | New Hyde Park | New York | 11040 | — |
| Cameron Dermatology | New York | New York | 10023 | — |
| Optima Research Boardman | Boardman | Ohio | 44512 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Wright State University | Fairborn | Ohio | 45324 | — |
| Apex Clinical Research Center LLC | Mayfield Heights | Ohio | 44124 | — |
| Clinical Research Ctr of Carolinas | Charleston | South Carolina | 29407 | — |
| Goodlettsville Dermatology Research | Goodlettsville | Tennessee | 37072-2301 | — |
| Accurate Clinical Research | Humble | Texas | 77346 | — |
| Austin Inst for Clinical Research | Pflugerville | Texas | 78660 | — |
| Center for Clinical Studies-Lee | Webster | Texas | 77598 | — |
| Care Access Alexandria | Arlington | Virginia | 22206 | — |
| Complexions Dermatology | Danville | Virginia | 24541 | — |
| Forefront Dermatology | Vienna | Virginia | 22182 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 94 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06840392, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06840392 live on ClinicalTrials.gov.