ClinicalTrials.gov record
Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
ClinicalTrials.gov ID: NCT06858839
Public ClinicalTrials.gov record NCT06858839. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
Study identification
- NCT ID
- NCT06858839
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 3,853 participants
Conditions and interventions
Conditions
Interventions
- Maridebart Cafraglutide Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 11, 2025
- Primary completion
- Jan 20, 2027
- Completion
- Apr 15, 2027
- Last update posted
- Oct 19, 2025
2025 – 2027
United States locations
- U.S. sites
- 74
- U.S. states
- 28
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group LLC | Anniston | Alabama | 36207 | — |
| Alliance For Multispecialty Research - Daphne | Daphne | Alabama | 36526 | — |
| Alliance for Multispecialty Research Mobile | Mobile | Alabama | 36608 | — |
| Avacare Foothills Research Center | Phoenix | Arizona | 85044 | — |
| Ark Clinical Research- Tustin | Fountain Valley | California | 92708 | — |
| Long Beach Clinical Trials Services Inc | Long Beach | California | 90806 | — |
| Ark Clinical Research- Long Beach | Long Beach | California | 90815 | — |
| Catalina Research Institute | Montclair | California | 91763 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Apex Clinical Research | San Diego | California | 92120 | — |
| Southern California Clinical Research | Santa Ana | California | 92701 | — |
| Diablo Clinical Research | Walnut Creek | California | 94598 | — |
| Yale School of Medicine | New Haven | Connecticut | 06520 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Indago Research and Health Center | Hialeah | Florida | 33012 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Clinical Neuroscience Solutions - Jacksonville | Jacksonville | Florida | 32256 | — |
| South Florida Wellness and Clinical Research Institute | Margate | Florida | 33063 | — |
| Optimus U Corporation | Miami | Florida | 33135 | — |
| Research Institute of South Florida | Miami | Florida | 33173 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Clinical Neuroscience Solutions - Orlando | Orlando | Florida | 32801 | — |
| Combined Research Orlando Phase I IV | Orlando | Florida | 32807 | — |
| Florida Institute for Clinical Research | Orlando | Florida | 32825 | — |
| Encore Medical Research of Weston LLC | Weston | Florida | 33331 | — |
| Center for Advanced Research and Education | Gainesville | Georgia | 30501 | — |
| Rophe Adult and Pediatric Medicine/Sky Clinical Research Network Group | Union City | Georgia | 30291 | — |
| East-West Medical Research | Honolulu | Hawaii | 96814 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Flourish Research - Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Endeavor Health Medical Group - Endocrinology and Diabetes- Skokie | Skokie | Illinois | 60077 | — |
| Evanston Premier Healthcare Research LLC | Skokie | Illinois | 60077 | — |
| Alliance for Multispecialty Research Newton | Newton | Kansas | 67114 | — |
| Louisville Metabolic and Atherosclerosis Research Center | Louisville | Kentucky | 40213 | — |
| Velocity Clinical Research - Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| Tandem Clinical Research - Marrero | Marrero | Louisiana | 70072 | — |
| Headlands Research - Detroit | Southfield | Michigan | 48034 | — |
| Prime Health and Wellness Sky Clinical Research Network Group | Fayette | Mississippi | 39069 | — |
| Alliance for Multispecialty Research - Kansas City | Kansas City | Missouri | 64114 | — |
| Palm Research Center Inc | Las Vegas | Nevada | 89128 | — |
| Vector Clinical Trials | Las Vegas | Nevada | 89128 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Velocity Clinical Research- Binghamton | Vestal | New York | 13850 | — |
| Accellacare of Hickory | Hickory | North Carolina | 28601 | — |
| Carolina Research Center Inc | Shelby | North Carolina | 28150 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Clinical Trial Investigator Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Velocity Clinical Research - Cincinnati | Cincinnati | Ohio | 45219 | — |
| Alliance for Multispecialty Research - Norman | Norman | Oklahoma | 73069 | — |
| Capital Area Research LLC | Newport | Pennsylvania | 17074 | — |
| Velocity Clinical Research - Providence | East Greenwich | Rhode Island | 02818 | — |
| Tribe Clinical Research LLC Dba Mountain View Clinical Research | Greenville | South Carolina | 29607 | — |
| New Phase Research and Development | Knoxville | Tennessee | 37909 | — |
| Accellacare US Inc., d/b/a Accellacare of Knoxville | Knoxville | Tennessee | 37938 | — |
| Elligo Clinical Research Center | Austin | Texas | 78704 | — |
| Cedar Health Research, LLC | Dallas | Texas | 75251 | — |
| Epic Medical Research - Texas | DeSoto | Texas | 75115 | — |
| Great Lakes Research Institute El Paso Research | El Paso | Texas | 79936 | — |
| Cedar Health Research, LLC | Euless | Texas | 76040 | — |
| Juno Research LLC | Houston | Texas | 77040 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Juno Research LLC | Houston | Texas | 77054 | — |
| Southern Endocrinology Associates PA | Mesquite | Texas | 75149 | — |
| Great Lakes Research Institute - McAllen Research | Pharr | Texas | 78557 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| Sugar Lakes Family Practice | Sugar Land | Texas | 77479 | — |
| Pantheon Clinical Research | Bountiful | Utah | 84010 | — |
| Alliance for Multispecialty Research Layton Research Center | Layton | Utah | 84041 | — |
| Chrysalis Clinical Research, LLC | St. George | Utah | 84770 | — |
| Washington Center for Weight Management and Research, Inc | Arlington | Virginia | 22206 | — |
| Health Research of Hampton Roads | Newport News | Virginia | 23606 | — |
| Selma Medical Associates | Winchester | Virginia | 22601 | — |
| Allegiance Research Specialists | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 169 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06858839, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 19, 2025 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06858839 live on ClinicalTrials.gov.