A Study to Investigate the Immunogenicity, Reactogenicity, and Safety of mRNA-1083 (Influenza and COVID-19) Vaccine in Adults ≥18 to <65 Years of Age
Public ClinicalTrials.gov record NCT06864143. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Observer-blind, Active-control Study to Evaluate the Immunogenicity, Reactogenicity, and Safety of mRNA-1083 (Influenza and COVID-19) Vaccine in Adults ≥18 to <65 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the immunogenicity, reactogenicity, and safety, of mRNA-1083 multicomponent influenza and COVID-19 vaccine in adults ≥18 to \<65 years of age.
Study identification
- NCT ID
- NCT06864143
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,320 participants
Conditions and interventions
Conditions
Interventions
- mRNA-1083 Composition 1 Dose A Lot A Biological
- mRNA-1083 Composition 1 Dose A Lot B Biological
- mRNA-1083 Composition 1 Dose B Biological
- mRNA-1083 Composition 1 Dose C Biological
- mRNA-1083 Composition 2 Dose A Biological
- mRNA-1083 Composition 2 Dose B Biological
- mRNA-1083 Composition 3 Dose A Biological
- mRNA-1083 Composition 3 Dose B Biological
- Influenza Vaccine Biological
- COVID-19 Vaccine Biological
- Investigational Influenza Vaccine Biological
- Investigational COVID-19 Vaccine Lot A Biological
- Investigational COVID-19 Vaccine Lot B Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 7, 2025 (Actual)
- Primary completion
- Oct 13, 2025 (Actual)
- Completion
- Oct 13, 2025 (Actual)
- Last update posted
- Oct 20, 2025
2025
United States locations
- U.S. sites
- 17
- U.S. states
- 15
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Headlands Research Scottsdale | Scottsdale | Arizona | 85260 | — |
| Artemis Research (Headlands) | San Diego | California | 92103 | — |
| Clinical Research Atlanta (Headlands) | Stockbridge | Georgia | 30281 | — |
| Velocity Clinical Research, Boise | Meridian | Idaho | 83642 | — |
| DM Clinical Research - Chicago | Melrose Park | Illinois | 60160 | — |
| Velocity Clinical Research, Lafayette | Lafayette | Louisiana | 70809 | — |
| Velocity Clinical Research, Rockville | Rockville | Maryland | 20854 | — |
| DM Clinical Research - Boston | Brookline | Massachusetts | 02446 | — |
| DM Clinical Research - Detroit | Southfield | Michigan | 48076 | — |
| Velocity Clinical Research, Norfolk | Norfolk | Nebraska | 68701 | — |
| Trial Management Associates, LLC | Wilmington | North Carolina | 28403 | — |
| Velocity Clinical Research, Cincinnati, Mt. Auburn | Cincinnati | Ohio | 45219 | — |
| Velocity Clinical Research, Cincinnati, Springdale | Cincinnati | Ohio | 45246 | — |
| DM Clinical Research - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Trial Management Associates, LLC | Myrtle Beach | South Carolina | 29572 | — |
| DM Clinical Research - Bellaire | Houston | Texas | 77081 | — |
| DM Clinical Research - Tomball | Tomball | Texas | 77375 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06864143, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 20, 2025 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06864143 live on ClinicalTrials.gov.