ClinicalTrials.gov record
4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
ClinicalTrials.gov ID: NCT06864988
Public ClinicalTrials.gov record NCT06864988. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Masked, Active-Controlled Trial of a Single Intravitreal Injection of 4D-150 in Adults With Macular Neovascularization Secondary to Age-Related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 3, Randomized, Double-Masked, Active-Controlled Trial in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration
Study identification
- NCT ID
- NCT06864988
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 480 participants
Conditions and interventions
Interventions
- 4D-150 IVT (3E10 vg/eye) Biological
- EYLEA® (aflibercept) Injection 2 mg (0.05mL) Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2, 2025
- Primary completion
- May 31, 2027
- Completion
- May 31, 2028
- Last update posted
- May 31, 2026
2025 – 2028
United States locations
- U.S. sites
- 91
- U.S. states
- 32
- U.S. cities
- 82
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barnet Dulaney Perkins Eye Center | Phoenix | Arizona | 85016 | — |
| Retinal Research Institute, LLC | Scottsdale | Arizona | 85254 | — |
| Retina Partners of Northwest Arkansas | Springdale | Arkansas | 72764 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Retina Associates of Southern California | Huntington Beach | California | 92647 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Retina Consultants of San Diego | Poway | California | 92064 | — |
| Kaiser Permanente-Riverside Medical Center | Riverside | California | 92505 | — |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95825 | — |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95840 | — |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | — |
| California Retina Consultants - Santa Barbara | Santa Barbara | California | 93103 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| University of Colorado, Denver | Aurora | Colorado | 80045 | — |
| Retina Consultants of Southern Colorado | Colorado Springs | Colorado | 80909 | — |
| RSC Research, LLC | Denver | Colorado | 80210 | — |
| Connecticut Eye Consultants | Danbury | Connecticut | 06810 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| Vitreo Retinal Associates | Gainesville | Florida | 34481 | — |
| Florida Retina Institute - Jacksonville | Jacksonville | Florida | 32216 | — |
| Florida Retina Consultants | Lakeland | Florida | 33805 | — |
| Florida Retina Institute | Orlando | Florida | 32806 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Retina Associates of Sarasota | Sarasota | Florida | 34232 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Georgia Retina PC | Marietta | Georgia | 30060 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Retina Associates - Elmhurst | Elmhurst | Illinois | 60126 | — |
| University Retina and Macula Associates, PC | Lemont | Illinois | 60439 | — |
| Illinois Retina Associates | Oak Park | Illinois | 60304 | — |
| Springfield Clinic | Springfield | Illinois | 62703 | — |
| Midwest Eye Institute | Carmel | Indiana | 46290 | — |
| Retina Associates of Kentucky | Lexington | Kentucky | 40509 | — |
| Haik Humble Eye Center | West Monroe | Louisiana | 71291 | — |
| Maine Eye Center | Portland | Maine | 04101 | — |
| Retina Group of Washington, Chevy Chase | Chevy Chase | Maryland | 20815 | — |
| Cumberland Valley Retina Consultants PC | Hagerstown | Maryland | 21740 | — |
| Mid Atlantic Retina Specialists - Hagerstown | Hagerstown | Maryland | 21740 | — |
| MD Medical Research | Waldorf | Maryland | 20745 | — |
| New England Retina Consultants | Springfield | Massachusetts | 01107 | — |
| Mississippi Retina Associates | Madison | Mississippi | 39110 | — |
| Deep Blue Retina Clinical Research | Southaven | Mississippi | 38671 | — |
| The Retina Institute | St Louis | Missouri | 63128 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| NJ Retina | Edison | New Jersey | 08820 | — |
| NJ Retina | Teaneck | New Jersey | 07666 | — |
| Eye Associates of New Mexico Vision Research Center | Albuquerque | New Mexico | 87109 | — |
| Retina-Vitreous Surgeons of Central New York | Liverpool | New York | 13088 | — |
| Vitreous Retina Macula Consultants of New York | New York | New York | 10022 | — |
| Retina Associates of Western New York | Rochester | New York | 14620 | — |
| Western Carolina Retinal Associate PA | Asheville | North Carolina | 28803 | — |
| Duke Eye Center | Durham | North Carolina | 27705 | — |
| North Carolina (NC) Retina Associates | Wake Forest | North Carolina | 27587 | — |
| Piedmont Retina Specialists - Winston Salem Office | Winston-Salem | North Carolina | 27157 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44122 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44130 | — |
| Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| Retina Vitreous Center | Edmond | Oklahoma | 73013 | — |
| Verum Research, LLC | Eugene | Oregon | 97401 | — |
| EyeHealth Northwest Peterkort | Portland | Oregon | 97225 | — |
| Mid Atlantic Retina | Bethlehem | Pennsylvania | 18017 | — |
| Erie Retina Research | Erie | Pennsylvania | 16507 | — |
| The Scheie Eye Institute | Philadelphia | Pennsylvania | 19104 | — |
| Charleston Neuroscience Center | Charleston | South Carolina | 29414 | — |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | — |
| Palmetto Retina Center | West Columbia | South Carolina | 29169 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Southeastern Retina Associates | Knoxville | Tennessee | 37763 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Texas Retina Associates | Arlington | Texas | 76012 | — |
| Austin Research Center for Retina | Austin | Texas | 78705 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Austin Clinical Research | Austin | Texas | 78750 | — |
| Retina & Vitreous of Texas, PLLC | Bellaire | Texas | 77401 | — |
| Retina Consultants of Houston | Bellaire | Texas | 77401 | — |
| Texas Retina Center | Houston | Texas | 77043 | — |
| Retina Associates of South Texas PA | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas San Antonio | San Antonio | Texas | 78240 | — |
| RCTX - Westover Hills Retina Center | San Antonio | Texas | 78251 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Retina Group of Washington, Fairfax | Fairfax | Virginia | 22031 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Retina Institute of Virginia | Richmond | Virginia | 23235 | — |
| Eye Clinic of Wisconsin | Wausau | Wisconsin | 54403 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06864988, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 31, 2026 · Synced Sep 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06864988 live on ClinicalTrials.gov.