The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

ClinicalTrials.gov ID: NCT06872892

Public ClinicalTrials.gov record NCT06872892. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced Apr 29, 2026, 12:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomised, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of BI 1291583 2.5 mg Administered Once Daily for up to 76 Weeks in Patients With Bronchiectasis (The AIRTIVITY™ Study)

Study identification

NCT ID: NCT06872892
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Boehringer Ingelheim; Industry
Enrollment: 1,755 participants

Conditions and interventions

Conditions

Bronchiectasis

Interventions

BI 1291583 Drug
Placebo matching BI 1291583 Drug

Drug

Eligibility (public fields only)

Age range: 12 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 8, 2025
Primary completion: Sep 13, 2028
Completion: Oct 11, 2028
Last update posted: Apr 28, 2026

2025 – 2028

United States locations

U.S. sites: 79
U.S. states: 34
U.S. cities: 70

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham	Birmingham	Alabama	35233	Recruiting
Providence Medical Group Alaska	Anchorage	Alaska	99508	Not yet recruiting
Dignity Health, St. Joseph's Hospital and Medical Center	Phoenix	Arizona	85013	Not yet recruiting
University of Arizona	Tucson	Arizona	85724	Recruiting
Newport Native MD, Inc	Newport Beach	California	92663	Recruiting
Paradigm Clinical Research - Redding	Redding	California	96001	Recruiting
University of California Davis	Sacramento	California	95817	Recruiting
University of California San Francisco	San Francisco	California	94143	Recruiting
Ventura County Medical Center	Ventura	California	93003	Not yet recruiting
National Jewish Health	Denver	Colorado	80206	Recruiting
Yale University School of Medicine	North Haven	Connecticut	06473	Recruiting
Georgetown University	Washington D.C.	District of Columbia	20007	Recruiting
Central Florida Pulmonary Group	Altamonte Springs	Florida	32701	Not yet recruiting
Meris Clinical Research-Brandon-69466	Brandon	Florida	33511	Recruiting
St. Francis Medical Institute	Clearwater	Florida	33765	Completed
North Florida/South Georgia Veterans Health System	Gainesville	Florida	32608	Not yet recruiting
University of Florida College of Medicine	Jacksonville	Florida	32209	Completed
Mayo Clinic - Florida	Jacksonville	Florida	32224	Recruiting
University of Miami	Miami	Florida	33136	Recruiting
Essence MD Research	Naples	Florida	34102	Recruiting
Premier Medical Associates	The Villages	Florida	32159	Recruiting
Cleveland Clinic Florida	Weston	Florida	33331	Recruiting
Emory University	Atlanta	Georgia	30342	Not yet recruiting
Augusta University	Augusta	Georgia	30912	Not yet recruiting
Northwestern University	Chicago	Illinois	60611	Not yet recruiting
Indiana University	Indianapolis	Indiana	46202	Not yet recruiting
University of Iowa Hospitals and Clinics	Iowa City	Iowa	52242	Not yet recruiting
University of Kansas Medical Center	Kansas City	Kansas	66160	Recruiting
Johns Hopkins Hospital	Baltimore	Maryland	21287	Recruiting
University of Maryland St. Joseph Medical Group Pulmonary Care and Sleep Medicine	Towson	Maryland	21286	Not yet recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
UMASS Memorial Medical Center	Worcester	Massachusetts	01655	Recruiting
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Mayo Clinic, Rochester	Rochester	Minnesota	55902	Recruiting
Health Partners Specialty	Saint Paul	Minnesota	55130	Recruiting
University Of Mississippi Medical Center	Jackson	Mississippi	39216	Recruiting
The Lung Research Center, LLC	Chesterfield	Missouri	63017	Completed
SSM Health Cardinal Glennon Children's Hospital	St Louis	Missouri	63104	Not yet recruiting
Washington University School of Medicine	St Louis	Missouri	63110	Not yet recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198-1230	Recruiting
Dartmouth-Hitchcock Medical Center	Lebanon	New Hampshire	03766	Not yet recruiting
Rutgers Robert Wood Johnson Medical School	New Brunswick	New Jersey	08901	Recruiting
New York Medical College - Hawthorne	Hawthorne	New York	10532	Recruiting
Northwell Health	New Hyde Park	New York	11040	Recruiting
New York University Langone Medical Center	New York	New York	10016	Not yet recruiting
Icahn School of Medicine at Mount Sinai	New York	New York	10029	Recruiting
Columbia University Medical Center-New York Presbyterian Hospital	New York	New York	10032	Recruiting
NewYork-Presbyterian/Weill Cornell Medical Center	New York	New York	10065	Not yet recruiting
The University of North Carolina at Chapel Hill	Chapel Hill	North Carolina	27514	Not yet recruiting
Stern Research Partners, LLC	Huntersville	North Carolina	28078	Recruiting
Pinehurst Medical Clinic, Inc. - East	Pinehurst	North Carolina	28374	Recruiting
Akron Children's Hospital	Akron	Ohio	44308	Not yet recruiting
University of Cincinnati	Cincinnati	Ohio	45219	Recruiting
University Hospitals Cleveland Medical Center	Cleveland	Ohio	44106	Recruiting
ProMedica Physicians Pulmonary and Sleep Medicine - Toledo	Toledo	Ohio	43606	Not yet recruiting
Oregon Health and Sciences University	Portland	Oregon	97239	Not yet recruiting
Clinical Research Associates of Central PA	DuBois	Pennsylvania	15801	Recruiting
University of Pennsylvania	Philadelphia	Pennsylvania	19104	Recruiting
Jefferson Health Honickman Center	Philadelphia	Pennsylvania	19107	Recruiting
Clinical Research of Rock Hill	Rock Hill	South Carolina	29732	Recruiting
Horizon Clinical Research Group	Cypress	Texas	77429	Recruiting
Baylor University Medical Center	Dallas	Texas	75246	Recruiting
University of Texas Southwestern Medical Center	Dallas	Texas	75390	Recruiting
El Paso Pulmonary Association	El Paso	Texas	79902	Recruiting
University of Texas Medical Branch at Galveston	Galveston	Texas	77555	Recruiting
Baylor College of Medicine	Houston	Texas	77030	Recruiting
Metroplex Pulmonary & Sleep Center	McKinney	Texas	75069	Recruiting
Methodist Heart and Lung Institute	San Antonio	Texas	78229	Not yet recruiting
University of Texas Health Science Center at San Antonio	San Antonio	Texas	78229	Recruiting
Element Research Group	San Antonio	Texas	78258	Completed
University of Texas Health Science Center at Tyler	Tyler	Texas	75708	Recruiting
Intermountain Healthcare	Murray	Utah	84107	Recruiting
University of Vermont	Burlington	Vermont	05401	Recruiting
Inova Fairfax Medical Campus	Falls Church	Virginia	22042	Recruiting
Virginia Commonwealth University Health Systems	Richmond	Virginia	23219	Recruiting
University of Washington	Seattle	Washington	98195	Recruiting
Providence Medical Research Center	Spokane	Washington	99204	Recruiting
University of Wisconsin	Madison	Wisconsin	53792	Recruiting
Froedtert and The Medical College of Wisconsin	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 414 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06872892, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 28, 2026 · Synced Apr 29, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06872892 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →