A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab

ClinicalTrials.gov ID: NCT06880744

Public ClinicalTrials.gov record NCT06880744. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced May 5, 2026, 5:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 3b, Multicenter, Randomized, Open-Label Study of Risankizumab Compared to Vedolizumab for the Treatment of Adult Subjects With Moderate to Severe Ulcerative Colitis Who Are Naïve to Targeted Therapies

Study identification

NCT ID: NCT06880744
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AbbVie; Industry
Enrollment: 530 participants

Conditions and interventions

Conditions

Ulcerative Colitis

Interventions

Risankizumab Drug
Vedolizumab Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 16, 2025
Primary completion: Aug 31, 2028
Completion: Aug 31, 2028
Last update posted: Mar 15, 2026

2025 – 2028

United States locations

U.S. sites: 74
U.S. states: 27
U.S. cities: 68

Facility	City	State	ZIP	Site status
Gastro Health Research - St. Vincent'S East /ID# 275089	Birmingham	Alabama	35235	Recruiting
Digestive Health Specialists /ID# 274785	Dothan	Alabama	36301	Recruiting
East View Medical Research /ID# 276222	Mobile	Alabama	36606	Recruiting
Arizona Health Research /ID# 274366	Chandler	Arizona	85225	Recruiting
UC San Diego Health System /ID# 273538	La Jolla	California	92037	Recruiting
Gastro Care Institute /ID# 274873	Lancaster	California	93534	Recruiting
UCLA Health - Digestive Health & Nutrition Clinic /ID# 274827	Los Angeles	California	90024	Recruiting
Hoag Memorial Hospital Presbyterian /ID# 274364	Newport Beach	California	92663	Recruiting
California Medical Research Associates /ID# 274787	Northridge	California	91324	Recruiting
uc davis medical center - patient support services building /ID# 274251	Sacramento	California	95817	Recruiting
Clinical Applications Laboratories - San Diego - 3rd Avenue /ID# 273527	San Diego	California	92103	Recruiting
Danbury Hospital, Western Connecticut Health Network /ID# 275277	Danbury	Connecticut	06810	Recruiting
Novum Research /ID# 273587	Clermont	Florida	34711	Recruiting
Hillcrest Medical Research /ID# 273593	DeLand	Florida	32720	Recruiting
Florida Research Institute /ID# 275196	Lakewood Rch	Florida	34211	Recruiting
Sanchez Clinical Research /ID# 273727	Miami	Florida	33157	Recruiting
Medical Professional Clinical Research /ID# 275208	Miami	Florida	33165	Recruiting
Sarkis Clinical Trials - Ocala /ID# 273595	Ocala	Florida	34474	Recruiting
Endoscopic Research, Inc. /ID# 273548	Orlando	Florida	32803	Recruiting
Digestive And Liver Center Of Florida - Orlando /ID# 276432	Orlando	Florida	32825	Recruiting
Emory University School Of Medicine - Atlanta /ID# 273522	Atlanta	Georgia	30322	Recruiting
Gi Alliance - Glenview /ID# 274270	Glenview	Illinois	60026	Recruiting
Illinois Gastroenterology Group /ID# 274280	Gurnee	Illinois	60031	Recruiting
Southwest Gastroenterology - Oak Lawn /ID# 273596	Oak Lawn	Illinois	60453	Recruiting
OSF St. Francis Medical Center /ID# 274391	Peoria	Illinois	61637-0001	Recruiting
Springfield Clinic Main Campus /ID# 273547	Springfield	Illinois	62703-2403	Recruiting
Gastroenterology Health Partners /ID# 276434	New Albany	Indiana	47150	Recruiting
Iowa Digestive Disease Center - Clive /ID# 274558	Clive	Iowa	50325	Recruiting
Cotton O'Neil Digestive Health Center /ID# 274394	Topeka	Kansas	66606-1539	Recruiting
Gastroenterology Health Partners, PLLC /ID# 276441	Louisville	Kentucky	40218	Recruiting
Tandem Clinical Research - Houma /ID# 274562	Houma	Louisiana	70363	Recruiting
Metropolitan Gastroenterology Associates - Metairie /ID# 274282	Metairie	Louisiana	70006	Recruiting
Pinnacle Gastroenterology /ID# 274991	Shreveport	Louisiana	71103	Recruiting
Louisiana Research Center, LLC /ID# 276443	Shreveport	Louisiana	71105	Recruiting
Velocity Clinical Research, Rockville /ID# 273599	Rockville	Maryland	20854-2931	Recruiting
Brigham & Womens Hospital /ID# 275266	Boston	Massachusetts	02115	Recruiting
Lucida Clinical Trials /ID# 275235	New Bedford	Massachusetts	02740	Recruiting
Huron Gastroenterology /ID# 274998	Ann Arbor	Michigan	48197	Recruiting
Mayo Clinic-Rochester /ID# 273606	Rochester	Minnesota	55905	Recruiting
Gi Associates - Gia And Endoscopy Center - Flowood /ID# 274285	Flowood	Mississippi	39232	Recruiting
Delta Gastroenterology & Endoscopy Center /ID# 275005	Southaven	Mississippi	38671	Recruiting
Columbia University Medical Center /ID# 273518	New York	New York	10032	Recruiting
New York Gastroenterology Associates - Upper East Side /ID# 273520	New York	New York	10075	Recruiting
Gastroenterology Group of Rochester /ID# 274283	Rochester	New York	14618	Recruiting
Digestive Health Partners - Biltmore Office /ID# 273594	Asheville	North Carolina	28801	Recruiting
Atrium Health - Morehead /ID# 274245	Charlotte	North Carolina	28204	Recruiting
Charlotte Gastroenterology And Hepatology - Randolph Road /ID# 274553	Charlotte	North Carolina	28207	Recruiting
Carolina Digestive Diseases And Endoscopy Center /ID# 274256	Greenville	North Carolina	27834	Recruiting
Digestive Disease Consultants - Brunswick /ID# 276445	Brunswick	Ohio	44212	Recruiting
Gastro Health /ID# 275082	Cincinnati	Ohio	45219	Recruiting
University Of Cincinnati Medical Center /ID# 273524	Cincinnati	Ohio	45219	Recruiting
The Ohio State University - Wexner Medical Center /ID# 274743	Columbus	Ohio	43212	Recruiting
Dayton Gastroenterology, Inc /ID# 273528	Dayton	Ohio	45415	Recruiting
Digestive Disease Associates, LTD - Wyomissing /ID# 273603	Wyomissing	Pennsylvania	19610	Recruiting
Gastroenterology Associates of Orangeburg /ID# 274559	Orangeburg	South Carolina	29118	Recruiting
Gastro One - Walnut Run Road /ID# 273551	Cordova	Tennessee	38018	Recruiting
Skyline Gastroenterology of West Tennessee /ID# 276461	Jackson	Tennessee	38301	Recruiting
GI associates of Northeast Tennessee /ID# 273758	Johnson City	Tennessee	37604	Recruiting
Tri-Cities Gastroenterology /ID# 275067	Kingsport	Tennessee	37663	Recruiting
Gastrointestinal Associates - Knoxville - Dowell Springs Boulevard /ID# 276447	Knoxville	Tennessee	37909	Recruiting
Quality Medical Research /ID# 273733	Nashville	Tennessee	37211	Recruiting
Amel Med /ID# 276439	Georgetown	Texas	78628	Recruiting
Digestive & Liver Disease Consultants /ID# 276454	Houston	Texas	77090	Recruiting
Katy Integrative Gastroenterology /ID# 274645	Katy	Texas	77494	Recruiting
Caprock Gastro Research - Lubbock - 80th Street /ID# 273778	Lubbock	Texas	79424	Recruiting
GI Alliance: Mansfield /ID# 274272	Mansfield	Texas	76063	Recruiting
Linq Research /ID# 274917	Pearland	Texas	77584	Recruiting
Tyler Research Institute, LLC /ID# 273585	Tyler	Texas	75701	Recruiting
Care Access - Ogden /ID# 274361	Ogden	Utah	84403	Recruiting
Gastroenterology Associates Of Tidewater - Chesapeake /ID# 276440	Chesapeake	Virginia	23320	Recruiting
Emeritas Research Group /ID# 276457	Lansdowne Town Center	Virginia	20176	Recruiting
Gi Alliance - Bellevue /ID# 274264	Bellevue	Washington	98004	Recruiting
Virginia Mason Hospital & Medical Center /ID# 274810	Seattle	Washington	98101	Recruiting
Washington Gastroenterology - Tacoma /ID# 274551	Tacoma	Washington	98405	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 196 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06880744, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 15, 2026 · Synced May 5, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06880744 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →