Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT06890598

Public ClinicalTrials.gov record NCT06890598. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 10:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Double-Blind, Placebo-controlled Study Assessing the Efficacy and Safety of Olomorasib in Combination With Standard of Care Immunotherapy in Participants With Resected or Unresectable KRAS G12C-Mutant, Non-Small Cell Lung Cancer - SUNRAY-02

Study identification

NCT ID: NCT06890598
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Eli Lilly and Company; Industry
Enrollment: 700 participants

Conditions and interventions

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

Durvalumab Drug
Olomorasib Drug
Pembrolizumab Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 26, 2025
Primary completion: Apr 30, 2029
Completion: Jan 31, 2032
Last update posted: Apr 19, 2026

2025 – 2032

United States locations

U.S. sites: 78
U.S. states: 29
U.S. cities: 63

Facility	City	State	ZIP	Site status
Clearview Cancer Institute	Huntsville	Alabama	35805	Recruiting
Infirmary Cancer Care	Mobile	Alabama	36607	Suspended
The University of Arizona Cancer Center - North Campus	Tucson	Arizona	85719	Recruiting
Highlands Oncology Group	Springdale	Arkansas	72762	Recruiting
UCLA Hematology/Oncology - Santa Monica	Los Angeles	California	90404	Not yet recruiting
Profound Research LLC	Oceanside	California	92056	Recruiting
University of California, Irvine (UCI) Health - UC Irvine Medical Center	Orange	California	92868	Not yet recruiting
Stanford Cancer Center	Palo Alto	California	94304	Recruiting
Kaiser Permanente San Diego Mission Road	San Diego	California	92108	Recruiting
BASS Cancer Center	Walnut Creek	California	94598	Recruiting
Hartford Hospital (HH)	Hartford	Connecticut	06102	Recruiting
Sibley Memorial Hospital	Washington D.C.	District of Columbia	20016	Not yet recruiting
Boca Raton Regional Hospital	Boca Raton	Florida	33486	Recruiting
Florida Cancer Specialists - South	Fort Myers	Florida	33901	Recruiting
University of Florida - Jacksonville	Jacksonville	Florida	32209	Recruiting
Miami Cancer Institute at Baptist Health, Inc.	Miami	Florida	33176	Recruiting
Ocala Oncology Center PL DBA Florida Cancer Affiliates - Ocala	Ocala	Florida	34474	Not yet recruiting
Florida Cancer Specialists North	St. Petersburg	Florida	33701-4553	Recruiting
Comprehensive Hematology Oncology	St. Petersburg	Florida	33709	Recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Recruiting
Florida Cancer Specialists East	West Palm Beach	Florida	33401	Recruiting
Winship Cancer Institute	Atlanta	Georgia	30322	Not yet recruiting
Northwestern Memorial Hospital	Chicago	Illinois	60611	Not yet recruiting
University of Illinois at Chicago	Chicago	Illinois	60612	Recruiting
University of Chicago Medical Center	Chicago	Illinois	60637	Recruiting
Captain James A. Lovell Federal Health Care Center	North Chicago	Illinois	60064	Recruiting
Springfield Clinic Main Campus	Springfield	Illinois	62703	Recruiting
Parkview Research Center at Parkview Regional Medical Center	Fort Wayne	Indiana	46845	Recruiting
Franciscan Health	Indianapolis	Indiana	46237	Recruiting
Baptist Health Lexington	Lexington	Kentucky	40503	Recruiting
Baptist Health Hamburg	Lexington	Kentucky	40509	Recruiting
CHI Saint Joseph Cancer Center - East	Lexington	Kentucky	40509	Recruiting
Mary Bird Perkins Cancer Center	Baton Rouge	Louisiana	70809	Recruiting
Ochsner Health Ochsner Cancer Center - Baton Rouge	Baton Rouge	Louisiana	70816	Recruiting
Ochsner Clinic Foundation	New Orleans	Louisiana	70121	Recruiting
New England Cancer Specialists	Westbrook	Maine	04092	Recruiting
University of Maryland	Baltimore	Maryland	21201	Not yet recruiting
Johns Hopkins Bayview Medical Center	Baltimore	Maryland	21224	Not yet recruiting
Reliant Medical Group	Worcester	Massachusetts	01606	Recruiting
Karmanos Cancer Institute	Detroit	Michigan	48201	Not yet recruiting
Missouri Baptist Medical Center	St Louis	Missouri	63131	Recruiting
Jefferson Health - Cherry Hill	Cherry Hill	New Jersey	08002	Recruiting
Sidney Kimmel Cancer Center - Washington Township	Sewell	New Jersey	08080	Recruiting
Columbia University Irving Medical Center	New York	New York	10032	Recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
Northport VA Medical Center	Northport	New York	11768	Not yet recruiting
Aultman Hospital	Canton	Ohio	44710	Not yet recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T	Columbus	Ohio	43210	Not yet recruiting
Providence Portland Medical Center	Portland	Oregon	97213	Recruiting
Providence St. Vincent Medical Center	Portland	Oregon	97225	Recruiting
Kaiser Permanente Interstate Medical Office Central	Portland	Oregon	97227	Recruiting
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office	Philadelphia	Pennsylvania	19107	Recruiting
Jefferson Hospital Northeast	Philadelphia	Pennsylvania	19114	Recruiting
AHN Allegheny General Hospital	Pittsburgh	Pennsylvania	15212	Recruiting
Medical University of South Carolina	Charleston	South Carolina	29425	Not yet recruiting
Lexington Medical Center	West Columbia	South Carolina	29169	Recruiting
Tennessee Oncology Chattanooga	Chattanooga	Tennessee	37404	Recruiting
University of Tennessee Medical Center	Knoxville	Tennessee	37920	Recruiting
Sarah Cannon Research Institute	Nashville	Tennessee	37203	Recruiting
SCRI Oncology Partners	Nashville	Tennessee	37203	Recruiting
Tennessee Oncology	Nashville	Tennessee	37203	Recruiting
The Center for Cancer and Blood Disorders	Fort Worth	Texas	76104	Recruiting
Houston Methodist Hospital	Houston	Texas	77030	Recruiting
University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
USO - Texas Oncology - San Antonio	San Antonio	Texas	78240	Recruiting
USO - Texas Oncology Gulf Coast	Sugar Land	Texas	77479	Recruiting
USO - US Oncology Research Network	The Woodlands	Texas	77380	Recruiting
The University of Vermont Medical Center Inc.	Burlington	Vermont	05405	Recruiting
University of Virginia Health System	Charlottesville	Virginia	22903	Recruiting
VCU Health Adult Outpatient Pavillion	Richmond	Virginia	23219	Recruiting
Swedish Cancer Institute - Edmonds	Edmonds	Washington	98026	Recruiting
Swedish Medical Center	Seattle	Washington	98104	Recruiting
Cancer Care Northwest - Vercler	Spokane Valley	Washington	99216	Recruiting
Northwest Cancer Specialists PC	Vancouver	Washington	98684	Recruiting
University Hospital and UW Health Clinics	Madison	Wisconsin	53792	Not yet recruiting
Medical College of Wisconsin	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 274 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06890598, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 19, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06890598 live on ClinicalTrials.gov.

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