Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Public ClinicalTrials.gov record NCT06891755. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphysema suffering from dyspnea due to hyperinflation despite optimal medical treatment. The Apreo BREATHE Airway Scaffold is a permanent implant designed to tent open native airways. The study will include up to 250 participants at up to 25 study centers located in the United States and Europe. Study subjects will be followed for 3 years. The main questions it aims to answer are: Is it safe? Does it work?
Study identification
- NCT ID
- NCT06891755
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 250 participants
Conditions and interventions
Interventions
Device · Other
Eligibility (public fields only)
- Age range
- 40 Years to 84 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 14, 2025
- Primary completion
- Sep 29, 2027
- Completion
- Dec 30, 2029
- Last update posted
- Apr 23, 2026
2025 – 2029
United States locations
- U.S. sites
- 18
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Recruiting |
| Banner Health | Gilbert | Arizona | 85234 | Recruiting |
| University of California at Davis | Sacramento | California | 95817 | Recruiting |
| Mayo Clinic | Jacksonville | Florida | 32224 | Recruiting |
| Orlando Health | Orlando | Florida | 32806 | Recruiting |
| University of Chicago | Chicago | Illinois | 60637 | Recruiting |
| OSF St Francis Medical Center | Peoria | Illinois | 61637 | Recruiting |
| University of Kansas Medical Center Research Institute | Kansas City | Kansas | 66160 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44103 | Recruiting |
| The Ohio State University | Columbus | Ohio | 43210 | Recruiting |
| Clinical Research Associates of Central Pennsylvania | DuBois | Pennsylvania | 15801 | Recruiting |
| Temple University | Philadelphia | Pennsylvania | 19140 | Recruiting |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | Recruiting |
| Houston Methodist/Primary Critical Care | Houston | Texas | 77030 | Recruiting |
| Inova Health Care Services | Falls Church | Virginia | 22042 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06891755, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 23, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06891755 live on ClinicalTrials.gov.