ClinicalTrials.gov record
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
ClinicalTrials.gov ID: NCT06909565
Public ClinicalTrials.gov record NCT06909565. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluation of Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention (V-INTERVENTION)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
V-INTERVENTION will evaluate the effectiveness of inclisiran in preventing major cardiovascular and limb events in patients receiving percutaneous coronary or peripheral arterial revascularization. Inclisiran is a subcutaneous, twice-yearly injection that is FDA-approved as an adjunct with statin therapy and on the market to lower LDL-C in high-risk populations.
Study identification
- NCT ID
- NCT06909565
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 6,000 participants
Conditions and interventions
Interventions
- Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL Drug
- Normal Saline (Placebo) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 22, 2025
- Primary completion
- Sep 30, 2029
- Completion
- Nov 30, 2029
- Last update posted
- Aug 27, 2026
2025 – 2029
United States locations
- U.S. sites
- 136
- U.S. states
- 36
- U.S. cities
- 125
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Cardiovascular LLC | Alexander City | Alabama | 35010 | Recruiting |
| Cardiology, PC | Birmingham | Alabama | 35211 | Recruiting |
| Heart Center Research, LLC | Huntsville | Alabama | 35801 | Recruiting |
| IMS Cardiology | Avondale | Arizona | 85392 | Recruiting |
| Cardiology Associates Research Group | Jonesboro | Arkansas | 72401 | Recruiting |
| Arkansas Cardiology | Little Rock | Arkansas | 72205 | Recruiting |
| Pacific Oaks Medical Group | Beverly Hills | California | 90211 | Recruiting |
| Cardiovascular Institute of San Diego | Chula Vista | California | 91911 | Recruiting |
| John Muir Medical Center - Concord Campus | Concord | California | 94520 | Recruiting |
| Valley Clinical Trials | Covina | California | 91723 | Withdrawn |
| Thrive Clinical Research Group | Glendora | California | 91740 | Recruiting |
| Radin Cardiovascular Medical Group, Inc | Newport Beach | California | 92663 | Recruiting |
| Valley Clinical Trials, LLC - Flourish Research | Northridge | California | 91325 | Recruiting |
| Riverside Community Hospital | Riverside | California | 92501 | Recruiting |
| Kaiser Permanente - San Diego | San Diego | California | 92123 | Recruiting |
| San Diego Cardiac Center | San Diego | California | 92123 | Recruiting |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Torrance | California | 90502 | Recruiting |
| The Heart Medical Group | Van Nuys | California | 91406 | Recruiting |
| FOMAT - West Coast Research Center | Ventura | California | 93030 | Recruiting |
| Interventional Cardiology Medical Group | West Hills | California | 91307 | Recruiting |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | Recruiting |
| Aurora Denver Cardiology Associates - Englewood | Englewood | Colorado | 80113 | Recruiting |
| ClinRe 001-001 | Thornton | Colorado | 80023 | Recruiting |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | Recruiting |
| Nuvance Health- Danbury Hospital | Danbury | Connecticut | 06810 | Recruiting |
| Cardiology Associates of Fairfield County | Stamford | Connecticut | 06305 | Recruiting |
| BayCare Medical Group | Clearwater | Florida | 33756 | Recruiting |
| Clearwater Cardiovascular Consultants | Clearwater | Florida | 33756 | Recruiting |
| Pioneer Clinical Studies | Coral Gables | Florida | 33134 | Recruiting |
| Arrow Clinical Trails | Daytona Beach | Florida | 32117 | Recruiting |
| UF Health Jacksonville | Jacksonville | Florida | 32209 | Recruiting |
| First Coast Cardiovascular Institute, PA | Jacksonville | Florida | 32256 | Recruiting |
| Clearwater Cardiovascular and Interventional Consultants- Bardmoor | Largo | Florida | 33777 | Recruiting |
| Inpatient Research Clinic, LLC | Miami Lakes | Florida | 33014 | Recruiting |
| Cardiovascular Institute of Northwest Florida | Panama City | Florida | 32405 | Recruiting |
| Gulf Coast Heart and Vascular | Panama City | Florida | 32405 | Recruiting |
| Charlotte Heart & Vascular Center, PA | Port Charlotte | Florida | 33948 | Recruiting |
| Clearwater Cardiovascular Consultants | Safety Harbor | Florida | 34695 | Active, not recruiting |
| Tampa Cardiovascular Interventions and Research | Tampa | Florida | 33614 | Recruiting |
| Northeast Georgia Heart Center, PC | Gainesville | Georgia | 30501 | Recruiting |
| Javara, Inc. | Peachtree City | Georgia | 30269 | Withdrawn |
| Atlanta Heart Specialists LLC | Tucker | Georgia | 30084 | Recruiting |
| University of Illinois Chicago | Chicago | Illinois | 60612 | Recruiting |
| Advocate Aurora Lutheran General Hospital | Park Ridge | Illinois | 60068 | Recruiting |
| Midwest Cardiovascular Research and Education Foundation | Elkhart | Indiana | 46514 | Recruiting |
| Heart Center of Lake County | Merrillville | Indiana | 46410 | Recruiting |
| Reid Physician Associates | Richmond | Indiana | 47374 | Recruiting |
| Iowa Heart Center | West Des Moines | Iowa | 50266 | Recruiting |
| Midwest Heart and Vascular Specialists | Overland Park | Kansas | 66211 | Recruiting |
| Research Integrity, LLC | Owensboro | Kentucky | 42303 | Recruiting |
| Grace Research, LLC | Bossier City | Louisiana | 71111 | Recruiting |
| Louisiana Heart Center | Covington | Louisiana | 70433 | Recruiting |
| Tulane School of Medicine | New Orleans | Louisiana | 70112 | Recruiting |
| Cardiovascular Solutions, LLC | Shreveport | Louisiana | 71103 | Recruiting |
| Monroe Research LLC | West Monroe | Louisiana | 71291 | Recruiting |
| Northern Light Eastern Maine Medical Center | Bangor | Maine | 04401 | Recruiting |
| MedStar Southern Maryland Hospital Center | Clinton | Maryland | 20735 | Recruiting |
| Capitol Cardiology Associates PA | Lanham | Maryland | 20706 | Recruiting |
| Shady Grove Adventist Hospital | Rockville | Maryland | 20850 | Recruiting |
| TidalHealth Peninsula Regional | Salisbury | Maryland | 21804 | Recruiting |
| Jadestone Clinical Research, LLC | Silver Spring | Maryland | 20904 | Recruiting |
| Washington Vascular Specialists - ClinRe 001-136 | Takoma Park | Maryland | 20912 | Recruiting |
| UMH-Sparrow Clinical Research Institute | Lansing | Michigan | 48912 | Recruiting |
| MyMichigan Medical Center Midland | Midland | Michigan | 48670 | Recruiting |
| Healthy Heart Cardiology at Rochester Hills (Advanced Cardiology Associates | Rochester Hills | Michigan | 48307 | Recruiting |
| Aspirus Saint Luke's Hospital | Duluth | Minnesota | 55805 | Recruiting |
| Essentia Health-SMMC | Duluth | Minnesota | 55805 | Recruiting |
| JAVARA Inc, - Mankato Clinic | Mankato | Minnesota | 56001 | Recruiting |
| Stern Cardiovascular | Southaven | Mississippi | 38671 | Recruiting |
| Cardiology Associates of North Mississippi | Tupelo | Mississippi | 38801 | Recruiting |
| University of Missouri Health Care | Columbia | Missouri | 65212 | Recruiting |
| CHI Health Nebraska Heart | Grand Island | Nebraska | 68803 | Recruiting |
| Bryan Heart | Lincoln | Nebraska | 68506 | Recruiting |
| CHI Health Nebraska Heart | Lincoln | Nebraska | 68526 | Recruiting |
| Methodist Physicians Clinic Heart Consultants | Omaha | Nebraska | 68114 | Recruiting |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | Recruiting |
| Advanced Heart Care LLC | Bridgewater | New Jersey | 08807 | Recruiting |
| Cardiovascular Associates of the Delaware Valley | Elmer | New Jersey | 08318 | Recruiting |
| Advanced Heart and Vascular Institute Of Hunterdon | Flemington | New Jersey | 08822 | Recruiting |
| Cardiovascular Associates of the Delaware Valley | Haddon Heights | New Jersey | 08035 | Recruiting |
| AtlantiCare Regional Medical Center | Pomona | New Jersey | 08240 | Recruiting |
| Cardiovascular Associates of the Delaware Valley | Sewell | New Jersey | 08080 | Recruiting |
| Presbyterian Heart Group | Albuquerque | New Mexico | 87106 | Recruiting |
| Capital Cardiology Associates | Albany | New York | 12211 | Recruiting |
| Sisters of Charity Hospital | Buffalo | New York | 14214 | Recruiting |
| Trinity Medical WNY, PC | Buffalo | New York | 14214 | Recruiting |
| Mount Sinai School of Medicine | New York | New York | 10029 | Recruiting |
| Hudson Valley Cardiovascular Practice PC | Poughkeepsie | New York | 12601 | Recruiting |
| University of Rochester Medical Center | Rochester | New York | 14642 | Recruiting |
| Richmond University Medical Center | Staten Island | New York | 10310 | Recruiting |
| Jacobi Medical Center | The Bronx | New York | 10461 | Recruiting |
| Asheville Cardiology Associates Research Department | Asheville | North Carolina | 28803 | Recruiting |
| Novant Health Clinical Research/Heart & Vascular Institute | Charlotte | North Carolina | 28204 | Recruiting |
| Mecklenburg Heart Specialists | Charlotte | North Carolina | 28207 | Recruiting |
| Javara Inc. | Fayetteville | North Carolina | 28304 | Recruiting |
| Moses H Cone Memorial Hospital | Greensboro | North Carolina | 27401 | Recruiting |
| Wake Forest University Health Sciences | High Point | North Carolina | 27262 | Recruiting |
| Duke Cardiology | Morrisville | North Carolina | 27560 | Recruiting |
| Duke Vascular Surgery and Vein Center at Brier Creek | Raleigh | North Carolina | 27617 | Recruiting |
| Novant Health Forsyth Medical Center | Winston-Salem | North Carolina | 27103 | Recruiting |
| Aultman Hospital | Canton | Ohio | 44710 | Recruiting |
| Heart House Research Foundation LLC | Springfield | Ohio | 45505 | Recruiting |
| ProMedica Toledo Hospital | Toledo | Ohio | 43606 | Recruiting |
| Genesis HealthCare System | Zanesville | Ohio | 43701 | Recruiting |
| South Oklahoma Heart Research, LLC | Oklahoma City | Oklahoma | 73135 | Recruiting |
| St. Luke's University Health Network | Bethlehem | Pennsylvania | 18015 | Recruiting |
| Capital Area Research LLC | Camp Hill | Pennsylvania | 17011 | Recruiting |
| Wellspan Chambersburg Hospital | Chambersburg | Pennsylvania | 17201 | Recruiting |
| Penn Lancaster General Health Research Institute | Lancaster | Pennsylvania | 17602 | Recruiting |
| Cardiology Associates of West Reading | West Reading | Pennsylvania | 19611 | Recruiting |
| WellSpan Heart and Vascular Research | York | Pennsylvania | 17403 | Recruiting |
| AnMed Health Medical Center | Anderson | South Carolina | 29621 | Recruiting |
| Monument Health Clinical Research | Rapid City | South Dakota | 57701 | Recruiting |
| Stern Cardiovascular Center | Germantown | Tennessee | 38138 | Recruiting |
| Ballad Health System | Greeneville | Tennessee | 37745 | Recruiting |
| Apex Research Foundation, LLC | Jackson | Tennessee | 38301 | Recruiting |
| The Jackson Clinic, PA | Jackson | Tennessee | 38305 | Recruiting |
| TriStar Centennial Medical Center | Nashville | Tennessee | 37203 | Recruiting |
| PharmaTex Research | Amarillo | Texas | 79106 | Recruiting |
| Amarillo Heart Clinical Research Institute, Inc. | Amarillo | Texas | 79124 | Recruiting |
| Austin Heart | Austin | Texas | 78705 | Recruiting |
| Javara inc. | Conroe | Texas | 77384 | Withdrawn |
| Vital Heart and Vein | Humble | Texas | 77338 | Recruiting |
| Texas Cardiology Associates of Houston | Kingwood | Texas | 77339 | Recruiting |
| Heart Institute of East Texas | Lufkin | Texas | 75904 | Recruiting |
| DHR Health Institute for Research | McAllen | Texas | 78504 | Recruiting |
| Austin Heart PLLC | Round Rock | Texas | 78681 | Recruiting |
| Austin Heart | San Marcos | Texas | 78666 | Recruiting |
| Northwest Houston Heart Center | Tomball | Texas | 77375 | Recruiting |
| Viva Heart and Vein | Tomball | Texas | 77375 | Recruiting |
| TPMG Clinical Research | Newport News | Virginia | 23606 | Recruiting |
| Chippenham Hospital | Richmond | Virginia | 23225 | Recruiting |
| Winchester Cardiology and Vascular Medicine | Winchester | Virginia | 22601 | Recruiting |
| MultiCare Institute for Research and Innovation | Puyallup | Washington | 98372 | Recruiting |
| MultiCare Institute for Research and Innovation | Tacoma | Washington | 98405 | Recruiting |
| Bellin Memorial Hospital | Green Bay | Wisconsin | 54301 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06909565, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 27, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06909565 live on ClinicalTrials.gov.