ClinicalTrials.gov record
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
ClinicalTrials.gov ID: NCT06931340
Public ClinicalTrials.gov record NCT06931340. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 10, 2026, 9:42 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Docetaxel Addition in Metastatic Castrate-Sensitive Prostate Cancer (ASPIRE)
Study identification
- NCT ID
- NCT06931340
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Alliance for Clinical Trials in Oncology
- Other
- Enrollment
- 1,260 participants
Conditions and interventions
Conditions
Interventions
- Androgen Therapy Drug
- Apalutamide Drug
- Biospecimen Collection Procedure
- Bone Scan Procedure
- Computed Tomography Procedure
- Docetaxel Drug
- Magnetic Resonance Imaging Procedure
- PSMA PET Scan Procedure
- Questionnaire Administration Other
Drug · Procedure · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2025
- Primary completion
- Nov 10, 2031
- Completion
- May 7, 2039
- Last update posted
- May 7, 2026
2025 – 2039
United States locations
- U.S. sites
- 186
- U.S. states
- 29
- U.S. cities
- 153
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner University Medical Center - Tucson | Tucson | Arizona | 85719 | Recruiting |
| University of Arizona Cancer Center-North Campus | Tucson | Arizona | 85719 | Recruiting |
| Kaiser Permanente Dublin | Dublin | California | 94568 | Recruiting |
| Kaiser Permanente-Fremont | Fremont | California | 94538 | Recruiting |
| Kaiser Permanente Fresno Orchard Plaza | Fresno | California | 93720 | Recruiting |
| UC San Diego Moores Cancer Center | La Jolla | California | 92093 | Recruiting |
| Kaiser Permanente- Modesto MOB II | Modesto | California | 95356 | Recruiting |
| Kaiser Permanente-Modesto | Modesto | California | 95356 | Recruiting |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | Recruiting |
| Eisenhower Medical Center | Rancho Mirage | California | 92270 | Recruiting |
| Kaiser Permanente-Roseville | Roseville | California | 95661 | Recruiting |
| Kaiser Permanente Downtown Commons | Sacramento | California | 95814 | Recruiting |
| Kaiser Permanente-South Sacramento | Sacramento | California | 95823 | Recruiting |
| UC San Diego Medical Center - Hillcrest | San Diego | California | 92103 | Recruiting |
| Kaiser Permanente-San Francisco | San Francisco | California | 94115 | Recruiting |
| Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | 95119 | Recruiting |
| Kaiser Permanente San Leandro | San Leandro | California | 94577 | Recruiting |
| Kaiser San Rafael-Gallinas | San Rafael | California | 94903 | Recruiting |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051 | Recruiting |
| Kaiser Permanente-Santa Rosa | Santa Rosa | California | 95403 | Recruiting |
| Kaiser Permanente-South San Francisco | South San Francisco | California | 94080 | Recruiting |
| Kaiser Permanente-Vallejo | Vallejo | California | 94589 | Recruiting |
| Kaiser Permanente-Walnut Creek | Walnut Creek | California | 94596 | Recruiting |
| Kaiser Permanente-Franklin | Denver | Colorado | 80205 | Recruiting |
| Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | 81501 | Recruiting |
| Kaiser Permanente-Rock Creek | Lafayette | Colorado | 80026 | Recruiting |
| Bayhealth Hospital Kent Campus | Dover | Delaware | 19901 | Recruiting |
| Bayhealth Hospital Sussex Campus | Milford | Delaware | 19963 | Recruiting |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Malcom Randall Veterans Administration Medical Center | Gainesville | Florida | 32610 | Recruiting |
| Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | 96819 | Recruiting |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | Recruiting |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | Recruiting |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | Recruiting |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | Recruiting |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83687 | Recruiting |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | Recruiting |
| Kootenai Clinic Cancer Services - Sandpoint | Sandpoint | Idaho | 83864 | Recruiting |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | Recruiting |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | Recruiting |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | Recruiting |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | Recruiting |
| Rush MD Anderson Cancer Center | Chicago | Illinois | 60612 | Recruiting |
| University of Illinois | Chicago | Illinois | 60612 | Recruiting |
| Carle at The Riverfront | Danville | Illinois | 61832 | Recruiting |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | Recruiting |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | Recruiting |
| Illinois CancerCare-Dixon | Dixon | Illinois | 61021 | Recruiting |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | Recruiting |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | Recruiting |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | Recruiting |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | Recruiting |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | Recruiting |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | Recruiting |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | Recruiting |
| Carle BroMenn Medical Center | Normal | Illinois | 61761 | Recruiting |
| Carle Cancer Institute Normal | Normal | Illinois | 61761 | Recruiting |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | Recruiting |
| HSHS Saint Elizabeth's Hospital | O'Fallon | Illinois | 62269 | Recruiting |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | Recruiting |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | Recruiting |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | Recruiting |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | Recruiting |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | Recruiting |
| Memorial Hospital East | Shiloh | Illinois | 62269 | Recruiting |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | Recruiting |
| Springfield Clinic | Springfield | Illinois | 62702 | Recruiting |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | Recruiting |
| Carle Cancer Center | Urbana | Illinois | 61801 | Recruiting |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | Recruiting |
| Mary Greeley Medical Center | Ames | Iowa | 50010 | Recruiting |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | Recruiting |
| McFarland Clinic - Boone | Boone | Iowa | 50036 | Suspended |
| Mercy Hospital | Cedar Rapids | Iowa | 52403 | Recruiting |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | Recruiting |
| McFarland Clinic - Trinity Cancer Center | Fort Dodge | Iowa | 50501 | Recruiting |
| McFarland Clinic - Jefferson | Jefferson | Iowa | 50129 | Suspended |
| McFarland Clinic - Marshalltown | Marshalltown | Iowa | 50158 | Recruiting |
| HaysMed | Hays | Kansas | 67601 | Recruiting |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | Recruiting |
| The University of Kansas Cancer Center - Olathe | Olathe | Kansas | 66061 | Recruiting |
| University of Kansas Cancer Center-Overland Park | Overland Park | Kansas | 66210 | Recruiting |
| Salina Regional Health Center | Salina | Kansas | 67401 | Recruiting |
| University of Kansas Health System Saint Francis Campus | Topeka | Kansas | 66606 | Recruiting |
| University of Kansas Hospital-Westwood Cancer Center | Westwood | Kansas | 66205 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | 48118 | Recruiting |
| OSF Saint Francis Hospital and Medical Group | Escanaba | Michigan | 49829 | Recruiting |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | Recruiting |
| Hurley Medical Center | Flint | Michigan | 48503 | Recruiting |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | Recruiting |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | Recruiting |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | Recruiting |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | Recruiting |
| Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | 56601 | Recruiting |
| Coborn Cancer Center at Saint Cloud Hospital | Saint Cloud | Minnesota | 56303 | Recruiting |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | Recruiting |
| Siteman Cancer Center at Saint Peters Hospital | City of Saint Peters | Missouri | 63376 | Recruiting |
| Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | 63141 | Recruiting |
| University Health Truman Medical Center | Kansas City | Missouri | 64108 | Recruiting |
| University of Kansas Cancer Center - Briarcliff | Kansas City | Missouri | 64116 | Recruiting |
| University of Kansas Cancer Center - North | Kansas City | Missouri | 64154 | Recruiting |
| University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri | 64064 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Mercy Hospital South | St Louis | Missouri | 63128 | Recruiting |
| Siteman Cancer Center-South County | St Louis | Missouri | 63129 | Recruiting |
| Siteman Cancer Center at Christian Hospital | St Louis | Missouri | 63136 | Recruiting |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | Recruiting |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | Recruiting |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | Recruiting |
| Saint Vincent Frontier Cancer Center | Billings | Montana | 59102 | Recruiting |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | Recruiting |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | Recruiting |
| Community Medical Center | Missoula | Montana | 59804 | Recruiting |
| Memorial Sloan Kettering Basking Ridge | Basking Ridge | New Jersey | 07920 | Recruiting |
| Jefferson Cherry Hill Hospital | Cherry Hill | New Jersey | 08002 | Recruiting |
| Memorial Sloan Kettering Monmouth | Middletown | New Jersey | 07748 | Recruiting |
| Memorial Sloan Kettering Bergen | Montvale | New Jersey | 07645 | Recruiting |
| Sidney Kimmel Cancer Center Washington Township | Sewell | New Jersey | 08080 | Recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Recruiting |
| Memorial Sloan Kettering Commack | Commack | New York | 11725 | Recruiting |
| Memorial Sloan Kettering Westchester | Harrison | New York | 10604 | Recruiting |
| Mount Sinai Hospital | New York | New York | 10029 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | Recruiting |
| Memorial Sloan Kettering Nassau | Uniondale | New York | 11553 | Recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Recruiting |
| FirstHealth of the Carolinas-Moore Regional Hospital | Pinehurst | North Carolina | 28374 | Recruiting |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | Recruiting |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | Recruiting |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | Recruiting |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | Recruiting |
| ProMedica Flower Hospital | Sylvania | Ohio | 43560 | Recruiting |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Saint Vincent Hospital | Erie | Pennsylvania | 16544 | Recruiting |
| Jefferson Hospital | Jefferson Hills | Pennsylvania | 15025 | Recruiting |
| Forbes Hospital | Monroeville | Pennsylvania | 15146 | Recruiting |
| Allegheny Valley Hospital | Natrona Heights | Pennsylvania | 15065 | Recruiting |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Jefferson Torresdale Hospital | Philadelphia | Pennsylvania | 19114 | Recruiting |
| Jefferson Methodist Hospital | Philadelphia | Pennsylvania | 19148 | Suspended |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | Recruiting |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | Recruiting |
| Guthrie Medical Group PC-Robert Packer Hospital | Sayre | Pennsylvania | 18840 | Recruiting |
| Wexford Health and Wellness Pavilion | Wexford | Pennsylvania | 15090 | Recruiting |
| Asplundh Cancer Pavilion | Willow Grove | Pennsylvania | 19090 | Recruiting |
| Saint Francis Hospital | Greenville | South Carolina | 29601 | Recruiting |
| Saint Francis Cancer Center | Greenville | South Carolina | 29607 | Recruiting |
| Self Regional Healthcare | Greenwood | South Carolina | 29646 | Recruiting |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | Recruiting |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | Recruiting |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | Recruiting |
| Intermountain Medical Center | Murray | Utah | 84107 | Recruiting |
| LDS Hospital | Salt Lake City | Utah | 84143 | Recruiting |
| Saint George Regional Medical Center | St. George | Utah | 84770 | Recruiting |
| Central Vermont Medical Center/National Life Cancer Treatment | Berlin Corners | Vermont | 05602 | Recruiting |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | Recruiting |
| University of Vermont and State Agricultural College | Burlington | Vermont | 05405 | Recruiting |
| Hematology Oncology Associates of Fredericksburg Inc | Fredericksburg | Virginia | 22408 | Recruiting |
| VCU Massey Cancer Center at Stony Point | Richmond | Virginia | 23235 | Recruiting |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | Recruiting |
| VCU Health Tappahannock Hospital | Tappahannock | Virginia | 22560 | Recruiting |
| West Virginia University Charleston Division | Charleston | West Virginia | 25304 | Recruiting |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | Recruiting |
| Ascension Saint Elizabeth Hospital | Appleton | Wisconsin | 54915 | Recruiting |
| Ascension Southeast Wisconsin Hospital - Elmbrook Campus | Brookfield | Wisconsin | 53045 | Recruiting |
| Ascension Calumet Hospital | Chilton | Wisconsin | 53014 | Recruiting |
| Ascension Saint Francis - Reiman Cancer Center | Franklin | Wisconsin | 53132 | Recruiting |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | Recruiting |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | Recruiting |
| William S Middleton VA Medical Center | Madison | Wisconsin | 53705 | Recruiting |
| Froedtert Menomonee Falls Hospital | Menomonee Falls | Wisconsin | 53051 | Recruiting |
| Ascension Columbia Saint Mary's Hospital Ozaukee | Mequon | Wisconsin | 53097 | Recruiting |
| Ascension Columbia Saint Mary's Hospital - Milwaukee | Milwaukee | Wisconsin | 53211 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
| Froedtert and MCW Moorland Reserve Health Center | New Berlin | Wisconsin | 53151 | Recruiting |
| Drexel Town Square Health Center | Oak Creek | Wisconsin | 53154 | Recruiting |
| Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | 54154 | Recruiting |
| Ascension Mercy Hospital | Oshkosh | Wisconsin | 54904 | Recruiting |
| Ascension All Saints Hospital | Racine | Wisconsin | 53405 | Recruiting |
| Saint Vincent Hospital Cancer Center at Sheboygan | Sheboygan | Wisconsin | 53081 | Recruiting |
| Sheboygan Physicians Group | Sheboygan | Wisconsin | 53081 | Recruiting |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235-1495 | Recruiting |
| Ascension Medical Group Southeast Wisconsin - Mayfair Road | Wauwatosa | Wisconsin | 53226 | Recruiting |
| Froedtert West Bend Hospital/Kraemer Cancer Center | West Bend | Wisconsin | 53095 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06931340, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06931340 live on ClinicalTrials.gov.