A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis
Public ClinicalTrials.gov record NCT06934226. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled and Ustekinumab Active Comparator-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Study identification
- NCT ID
- NCT06934226
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Enrollment
- 752 participants
Conditions and interventions
Conditions
Interventions
- JNJ-77242113 Drug
- Matching Placebo to JNJ-77242113 Drug
- Matching Placebo to Ustekinumab Drug
- Ustekinumab Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 14, 2025
- Primary completion
- Nov 16, 2025
- Completion
- Aug 19, 2027
- Last update posted
- Apr 12, 2026
2025 – 2027
United States locations
- U.S. sites
- 48
- U.S. states
- 23
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research Inc | Birmingham | Alabama | 35244 | — |
| California Dermatology & Clinical Research Institute | Encinitas | California | 92024 | — |
| T Joseph Raoof Md Inc | Encino | California | 91436 | — |
| First OC Dermatology | Fountain Valley | California | 92708 | — |
| Dermatologist Medical Group of North County, Inc. | Oceanside | California | 92056 | — |
| NorCal Clinical Research | Rocklin | California | 95765 | — |
| Integrative Skin Science and Research | Sacramento | California | 95815 | — |
| MedDerm Associates | San Diego | California | 92103 | — |
| Southern California Dermatology | Santa Ana | California | 92701 | — |
| Olive View-UCLA Education & Research Institute | Sylmar | California | 91342 | — |
| University of Conn Health Center | Farmington | Connecticut | 06030 | — |
| Driven Research LLC | Coral Gables | Florida | 33134 | — |
| Bioclinical Research Alliance Inc. | Miami | Florida | 33155 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Forcare Clinical Research Inc | Tampa | Florida | 33613 | — |
| Hamilton Research LLC | Alpharetta | Georgia | 30022 | — |
| Northshore Medical Group | Skokie | Illinois | 60076 | — |
| Indiana Clinical Trial Center | Plainfield | Indiana | 46168 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Equity Medical | Bowling Green | Kentucky | 42104 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Metro Boston Clinical Partners | Brighton | Massachusetts | 02135 | — |
| The Derm Institute of West Michigan | Caledonia | Michigan | 49316 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Hamzavi Dermatology | Fort Gratiot | Michigan | 48059 | — |
| Somerset Skin Centre | Troy | Michigan | 48084 | — |
| Minnesota Clinical Study Center | New Brighton | Minnesota | 55112 | — |
| Cleaver Dermatology | Kirksville | Missouri | 63501 | — |
| MediSearch Clinical Trials | Saint Joseph | Missouri | 64506 | — |
| Mount Sinai Doctors Dermatology | New York | New York | 10028 | — |
| Sadick Research Group | New York | New York | 10075 | — |
| Wilmington Dermatology Center | Wilmington | North Carolina | 28405 | — |
| Optima Research | Boardman | Ohio | 44512 | — |
| Apex Dermatology Mayfield Heights | Mayfield Heights | Ohio | 44124 | — |
| Oregon Medical Research Center | Portland | Oregon | 97201 | — |
| Oregon Dermatology and Research Center | Portland | Oregon | 97210 | — |
| Clinical Research Philadelphia | Philadelphia | Pennsylvania | 19114 | — |
| UPMC Department of Dermatology | Pittsburgh | Pennsylvania | 15213 | — |
| Health Concepts | Rapid City | South Dakota | 57702 | — |
| Advanced Research Experts PLLC | Nashville | Tennessee | 37211 | — |
| Arlington Research Center, Inc. | Arlington | Texas | 76011 | — |
| Modern Research Associates PLLC | Dallas | Texas | 75231 | — |
| Center for Clinical Studies 1 | Houston | Texas | 77004 | — |
| Progressive Clinical Research | San Antonio | Texas | 78213 | — |
| Texas Dermatology and Laser Specialists | San Antonio | Texas | 78218 | — |
| Center for Clinical Studies | Webster | Texas | 77598 | — |
| Kalo Clinical Research | West Valley City | Utah | 84120 | — |
| Frontier Derm Partners CRO, LLC | Mill Creek | Washington | 98012 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 112 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06934226, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced May 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06934226 live on ClinicalTrials.gov.