A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)
Public ClinicalTrials.gov record NCT06941844. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled, 12-Week Study (Part A) With a 40-Week Open-label Extension (Part B) Evaluating the Efficacy and Safety of Oral DT120 Compared to Placebo in the Treatment of Adults With Major Depressive Disorder - Emerge
Study identification
- NCT ID
- NCT06941844
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Definium Therapeutics US, Inc.
- Industry
- Enrollment
- 149 participants
Conditions and interventions
Conditions
Interventions
- Placebo Other
- DT120 Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 18 Years to 74 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 13, 2025
- Primary completion
- May 19, 2026
- Completion
- Jan 31, 2027
- Last update posted
- Jun 28, 2026
2025 – 2027
United States locations
- U.S. sites
- 25
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Preferred Research Partner | Fayetteville | Arkansas | 72703 | — |
| Preferred Research Partners, Inc | Little Rock | Arkansas | 72211 | — |
| Kadima Neuropsychiatry Institute | La Jolla | California | 92037 | — |
| Psychedelic Science Institute | Santa Monica | California | 90404 | — |
| Mountain View Clinical Research, Inc | Denver | Colorado | 80209 | — |
| Clinical Neuroscience Solutions, Inc | Jacksonville | Florida | 32256 | — |
| Clinical Neuroscience Solutions, Inc | Orlando | Florida | 32801 | — |
| Charter Research | Orlando | Florida | 32803 | — |
| Uptown Research | Chicago | Illinois | 60640 | — |
| Sheppard Pratt | Baltimore | Maryland | 21204 | — |
| Adams Clinical Boston | Boston | Massachusetts | 02116 | — |
| Adams Clinical | Watertown | Massachusetts | 02472 | — |
| University of Missouri | Columbia | Missouri | 65212 | — |
| Cenexel HRI | Berlin | New Jersey | 08053 | — |
| Adams Clinical Harlem | New York | New York | 10029 | — |
| Columbia - New York State Psychiatric Institute | New York | New York | 10032 | — |
| Neuro-Behavioral Clinical Research | Canton | Ohio | 44720 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Adams Clinical Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Clinical Neuroscience Solutions, Inc | Memphis | Tennessee | 38119 | — |
| Dell Medical School, University of Texas at Austin | Austin | Texas | 78712 | — |
| Austin Clinical Trial Partners | Austin | Texas | 78737 | — |
| FutureSearch Trials of Dallas | Dallas | Texas | 75231 | — |
| Cedar Clinical Research | Murray | Utah | 84020 | — |
| Memory Clinic, Inc | Bennington | Vermont | 05201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06941844, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 28, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06941844 live on ClinicalTrials.gov.