Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Public ClinicalTrials.gov record NCT06961214. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study of the Efficacy and Safety of Depemokimab in Adult Participants With COPD With Type 2 Inflammation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Depemokimab is being developed as a treatment for individuals with moderate to severe COPD. The aim of this study is to assess the efficacy and safety of depemokimab compared as an add-on medicine in participants with uncontrolled moderate to severe COPD with type 2 inflammation.
Study identification
- NCT ID
- NCT06961214
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 960 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2025
- Primary completion
- Aug 20, 2029
- Completion
- Aug 20, 2029
- Last update posted
- Apr 8, 2026
2025 – 2029
United States locations
- U.S. sites
- 54
- U.S. states
- 19
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Sheffield | Alabama | 35660 | Recruiting |
| GSK Investigational Site | Aurora | Colorado | 80012 | Recruiting |
| GSK Investigational Site | Brooksville | Florida | 346135 | Recruiting |
| GSK Investigational Site | Doral | Florida | 33172 | Recruiting |
| GSK Investigational Site | Fort Lauderdale | Florida | 33316 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33122 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33125 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33155 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33165 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33175 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33176 | Recruiting |
| GSK Investigational Site | Miami Lakes | Florida | 33016 | Recruiting |
| GSK Investigational Site | Naples | Florida | 34102 | Recruiting |
| GSK Investigational Site | New Port Richey | Florida | 34653 | Recruiting |
| GSK Investigational Site | Ocala | Florida | 34471 | Recruiting |
| GSK Investigational Site | Orlando | Florida | 32825 | Recruiting |
| GSK Investigational Site | Ormond Beach | Florida | 32174 | Recruiting |
| GSK Investigational Site | Palmetto Bay | Florida | 33157 | Recruiting |
| GSK Investigational Site | St. Petersburg | Florida | 33704 | Recruiting |
| GSK Investigational Site | Adairsville | Georgia | 30103 | Recruiting |
| GSK Investigational Site | Cordele | Georgia | 31015 | Recruiting |
| GSK Investigational Site | East Point | Georgia | 30344 | Recruiting |
| GSK Investigational Site | Morrow | Georgia | 30260 | Recruiting |
| GSK Investigational Site | Boise | Idaho | 83702 | Recruiting |
| GSK Investigational Site | Chicago | Illinois | 60608 | Recruiting |
| GSK Investigational Site | Baton Rouge | Louisiana | 70816 | Recruiting |
| GSK Investigational Site | Lafayette | Louisiana | 70506 | Recruiting |
| GSK Investigational Site | Shreveport | Louisiana | 71105 | Recruiting |
| GSK Investigational Site | Bangor | Maine | 04401 | Recruiting |
| GSK Investigational Site | Rockville | Maryland | 20854 | Recruiting |
| GSK Investigational Site | Allen Park | Michigan | 48101 | Recruiting |
| GSK Investigational Site | Detroit | Michigan | 48202 | Recruiting |
| GSK Investigational Site | Garden City | Michigan | 48135 | Recruiting |
| GSK Investigational Site | Troy | Michigan | 48085 | Recruiting |
| GSK Investigational Site | Las Vegas | Nevada | 89144 | Recruiting |
| GSK Investigational Site | Moorestown | New Jersey | 08057 | Recruiting |
| GSK Investigational Site | Sewell | New Jersey | 08080 | Recruiting |
| GSK Investigational Site | Mount Kisco | New York | 10549 | Recruiting |
| GSK Investigational Site | New Windsor | New York | 12553 | Recruiting |
| GSK Investigational Site | Shelby | North Carolina | 28152 | Recruiting |
| GSK Investigational Site | DuBois | Pennsylvania | 15801 | Recruiting |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19140 | Recruiting |
| GSK Investigational Site | Spartanburg | South Carolina | 29303 | Recruiting |
| GSK Investigational Site | Union | South Carolina | 29379 | Recruiting |
| GSK Investigational Site | Knoxville | Tennessee | 37919 | Recruiting |
| GSK Investigational Site | Austin | Texas | 78744 | Recruiting |
| GSK Investigational Site | Dallas | Texas | 75254 | Recruiting |
| GSK Investigational Site | El Paso | Texas | 79902-1123 | Recruiting |
| GSK Investigational Site | Houston | Texas | 77094 | Recruiting |
| GSK Investigational Site | Lampasas | Texas | 76550 | Recruiting |
| GSK Investigational Site | Richmond | Texas | 77407 | Recruiting |
| GSK Investigational Site | San Antonio | Texas | 78229 | Recruiting |
| GSK Investigational Site | Webster | Texas | 77598 | Recruiting |
| GSK Investigational Site | Morgantown | West Virginia | 26505-0423 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 100 non-U.S. sites.
Recently updated Pulmonary Disease, Chronic Obstructive trials
Other public records listing Pulmonary Disease, Chronic Obstructive. Sorted by last update posted; newest first. Not a recommendation.
- NCT07759245: A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) Not yet recruiting
- NCT07177339: eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation Recruiting
- NCT07714252: Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD Not yet recruiting
- NCT05718102: Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD Active, not recruiting
- NCT04669743: Innate Immunity in Ozone-induced Airway Inflammation in COPD Active, not recruiting
- NCT05592847: A Study of the Effect of a Nurse Navigator Program on High Risk Patients Not yet recruiting
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06961214, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 8, 2026 · Synced Jul 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06961214 live on ClinicalTrials.gov.