ClinicalTrials.gov record
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
ClinicalTrials.gov ID: NCT06966453
Public ClinicalTrials.gov record NCT06966453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 10:43 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 1b/2, OPEN-LABEL, MULTICOHORT STUDY OF DISITAMAB VEDOTIN IN ADULTS WITH HER2 EXPRESSING ADVANCED BREAST CANCER
Study identification
- NCT ID
- NCT06966453
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Interventions
- Disitamab vedotin Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 29, 2025
- Primary completion
- Oct 24, 2027
- Completion
- Jan 26, 2030
- Last update posted
- Apr 20, 2026
2025 – 2030
United States locations
- U.S. sites
- 134
- U.S. states
- 14
- U.S. cities
- 108
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Cancer Center, PC | Daphne | Alabama | 36526 | Recruiting |
| Southern Cancer Center, PC | Foley | Alabama | 36535 | Recruiting |
| Southern Cancer Center, PC | Mobile | Alabama | 36608 | Recruiting |
| Banner Gateway Medical Center | Gilbert | Arizona | 85234 | Not yet recruiting |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | Not yet recruiting |
| Los Angeles Cancer Network - Anaheim | Anaheim | California | 92805 | Recruiting |
| City of Hope National Medical Center | Duarte | California | 91010 | Not yet recruiting |
| Los Angeles Cancer Network | Fountain Valley | California | 92708 | Recruiting |
| Los Angeles Hematology Oncology Medical Group | Glendale | California | 91204 | Recruiting |
| City of Hope at Irvine Lennar | Irvine | California | 92618 | Not yet recruiting |
| Los Angeles Cancer Network | Los Angeles | California | 90017 | Recruiting |
| Valkyrie Clinical Trials | Los Angeles | California | 90067 | Recruiting |
| Mission Community Hospital (Satellite Site) | Los Angeles | California | 91402 | Recruiting |
| Clinical and Translational Research Unit (CTRU) | Palo Alto | California | 94304 | Recruiting |
| Stanford Cancer Center | Palo Alto | California | 94304 | Recruiting |
| Stanford Women's Cancer Center | Palo Alto | California | 94304 | Recruiting |
| Stanford Health Care, Investigational Drug Service | Stanford | California | 94305 | Recruiting |
| Los Angeles Hematology Oncology Medical Group | Van Nuys | California | 91405 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Aurora | Colorado | 80012 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Boulder | Colorado | 80303 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Centennial | Colorado | 80112 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Colorado Springs | Colorado | 80907 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Colorado Springs | Colorado | 80923 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Denver | Colorado | 80220 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Englewood | Colorado | 80113 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Lakewood | Colorado | 80228 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Littleton | Colorado | 80120 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Lone Tree | Colorado | 80124 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Longmont | Colorado | 80504 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Pueblo | Colorado | 81003 | Recruiting |
| Rocky Mountain Cancer Centers, LLP | Thornton | Colorado | 80260 | Recruiting |
| Smilow Cancer Hospital - Derby | Derby | Connecticut | 06418 | Recruiting |
| Smilow Cancer Hospital - Fairfield | Fairfield | Connecticut | 06824 | Recruiting |
| Smilow Cancer Hospital - Glastonbury | Glastonbury | Connecticut | 06033 | Recruiting |
| Smilow Cancer Hospital - Greenwich | Greenwich | Connecticut | 06830 | Recruiting |
| Smilow Cancer Hospital - Guilford | Guilford | Connecticut | 06437 | Recruiting |
| Smilow Cancer Hospital at St. Francis | Hartford | Connecticut | 06105 | Recruiting |
| Smilow Cancer Hospital - Yale New Haven Health | New Haven | Connecticut | 06510 | Recruiting |
| Yale-New Haven Hospital | New Haven | Connecticut | 06510 | Recruiting |
| Yale University - Smilow Cancer Hospital; C/O Thomas Ferencz, RPh, BCOP | New Haven | Connecticut | 06511 | Recruiting |
| Yale School of Medicine | New Haven | Connecticut | 06520 | Recruiting |
| Smilow Cancer Hospital - North Haven | North Haven | Connecticut | 06473 | Recruiting |
| Smilow Cancer Hospital - Long Ridge | Stamford | Connecticut | 06902 | Recruiting |
| Smilow Cancer Hospital - Torrington | Torrington | Connecticut | 06790 | Recruiting |
| Smilow Cancer Hospital - Trumbull | Trumbull | Connecticut | 06611 | Recruiting |
| Smilow Cancer Hospital - Waterbury | Waterbury | Connecticut | 06708 | Recruiting |
| Smilow Cancer Hospital - Waterford | Waterford | Connecticut | 06385 | Recruiting |
| Georgetown University Medical Center - Department of Pharmacy, Oncology Pharmacy | Washington D.C. | District of Columbia | 20007 | Recruiting |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | Recruiting |
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | Recruiting |
| Florida Cancer Specialists | Clearwater | Florida | 33761 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center - The Lennar Foundation Medical Center | Coral Gables | Florida | 33146 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center - Coral Springs | Coral Springs | Florida | 33065 | Not yet recruiting |
| University of Miami Hospital and Clinics - Deerfield Beach | Deerfield Beach | Florida | 33442 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center- Doral | Doral | Florida | 33166 | Not yet recruiting |
| Florida Cancer Specialists | Gainesville | Florida | 32605 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center - Hollywood | Hollywood | Florida | 33021 | Not yet recruiting |
| Florida Cancer Specialists | Largo | Florida | 33770 | Not yet recruiting |
| Florida Cancer Specialists | Lecanto | Florida | 34461 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | Not yet recruiting |
| University of Miami Hospital and Clinics | Miami | Florida | 33136 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center - Kendall | Miami | Florida | 33176 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center - Sole Mia | North Miami | Florida | 33181 | Not yet recruiting |
| Florida Cancer Specialists | Ocala | Florida | 34474 | Not yet recruiting |
| Florida Cancer Specialists | Orange City | Florida | 32763 | Not yet recruiting |
| Florida Cancer Specialists | Orlando | Florida | 32806 | Not yet recruiting |
| Sylvester Comprehensive Cancer Center - Plantation | Plantation | Florida | 33324 | Not yet recruiting |
| Florida Cancer Specialists | St. Petersburg | Florida | 33705 | Not yet recruiting |
| Florida Cancer Specialists | Tallahassee | Florida | 32308 | Not yet recruiting |
| Florida Cancer Specialists | Tampa | Florida | 33607 | Not yet recruiting |
| Florida Cancer Specialists | Tavares | Florida | 32778 | Not yet recruiting |
| Florida Cancer Specialists | The Villages | Florida | 32159 | Not yet recruiting |
| Florida Cancer Specialists | Trinity | Florida | 34655 | Not yet recruiting |
| Florida Cancer Specialists | West Palm Beach | Florida | 33401 | Not yet recruiting |
| Florida Cancer Specialists | Winter Park | Florida | 32789 | Not yet recruiting |
| Winship Cancer Institute @ Emory University Hospital Midtown | Atlanta | Georgia | 30308 | Recruiting |
| Emory Clinic Investigational Drug Services | Atlanta | Georgia | 30322 | Recruiting |
| Emory University Hospital | Atlanta | Georgia | 30322 | Recruiting |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | Recruiting |
| Oncology Associates of Oregon, P.C. | Albany | Oregon | 97321 | Recruiting |
| Oncology Associates of Oregon, P.C. | Corvallis | Oregon | 97330 | Recruiting |
| Oncology Associates of Oregon, P.C. | Eugene | Oregon | 97401 | Recruiting |
| Oncology Associates of Oregon, P.C. | Springfield | Oregon | 97477 | Recruiting |
| Alliance Cancer Specialists, PC | Bensalem | Pennsylvania | 19020 | Recruiting |
| Alliance Cancer Specialists, PC | Doylestown | Pennsylvania | 18901 | Recruiting |
| Alliance Cancer Specialists, PC | Horsham | Pennsylvania | 19044 | Recruiting |
| Alliance Cancer Specialists, PC | Langhorne | Pennsylvania | 19047 | Recruiting |
| Alliance Cancer Specialists, PC | Media | Pennsylvania | 19063 | Recruiting |
| Alliance Cancer Specialists, PC | Sellersville | Pennsylvania | 18960 | Recruiting |
| Alliance Cancer Specialists, PC | Wynnewood | Pennsylvania | 19096 | Recruiting |
| Sarah Cannon Research Institute - Pharmacy | Nashville | Tennessee | 37203 | Recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| Texas Oncology-Northeast Texas | Allen | Texas | 75013 | Recruiting |
| Texas Oncology - DFW | Arlington | Texas | 76012 | Recruiting |
| Texas Oncology - DFW | Arlington | Texas | 76014 | Recruiting |
| Texas Oncology - DFW | Bedford | Texas | 76022 | Recruiting |
| Texas Oncology - DFW | Dallas | Texas | 75203 | Recruiting |
| Texas Oncology - DFW | Dallas | Texas | 75230 | Recruiting |
| Texas Oncology - DFW | Dallas | Texas | 75231 | Recruiting |
| Texas Oncology - DFW | Dallas | Texas | 75237 | Recruiting |
| Texas Oncology - DFW | Dallas | Texas | 75246 | Recruiting |
| Texas Oncology-Northeast Texas | Denison | Texas | 75020 | Recruiting |
| Texas Oncology-Northeast Texas | Denton | Texas | 76201 | Recruiting |
| Texas Oncology-Northeast Texas | Flower Mound | Texas | 75028 | Recruiting |
| Texas Oncology - DFW | Fort Worth | Texas | 76104 | Recruiting |
| Texas Oncology - DFW | Grapevine | Texas | 76051 | Recruiting |
| US Oncology Investigation Products Center(IPC) | Irving | Texas | 75063 | Recruiting |
| US Oncology Investigational Product Center (IPC) | Irving | Texas | 75063 | Recruiting |
| Texas Oncology-Northeast Texas | Lewisville | Texas | 75056 | Recruiting |
| Texas Oncology-Northeast Texas | Longview | Texas | 75601 | Recruiting |
| Texas Oncology-Northeast Texas | McKinney | Texas | 75071 | Recruiting |
| Texas Oncology-Northeast Texas | Palestine | Texas | 75801 | Recruiting |
| Texas Oncology-Northeast Texas | Paris | Texas | 75460 | Recruiting |
| Texas Oncology - DFW | Plano | Texas | 75075 | Recruiting |
| Texas Oncology - DFW | Plano | Texas | 75093 | Recruiting |
| Texas Oncology - San Antonio | San Antonio | Texas | 78217 | Recruiting |
| Texas Oncology - San Antonio | San Antonio | Texas | 78240 | Recruiting |
| Texas Oncology-Northeast Texas | Tyler | Texas | 75702 | Recruiting |
| Virginia Cancer Specialists, PC | Arlington | Virginia | 22201 | Recruiting |
| Oncology & Hematology Associates of Southwest Virginia Inc dba Blue Ridge Cancer Care | Blacksburg | Virginia | 24060 | Recruiting |
| Virginia Oncology Associates | Chesapeake | Virginia | 23320 | Recruiting |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | Recruiting |
| Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Low Moor | Virginia | 24457 | Recruiting |
| Virginia Cancer Specialists, PC | Manassas | Virginia | 20110 | Recruiting |
| Virginia Oncology Associates | Newport News | Virginia | 23606 | Recruiting |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | Recruiting |
| Virginia Cancer Specialists, PC | Reston | Virginia | 20190 | Recruiting |
| Oncology & Hematology Associates of Southwest Virginia Inc dba Blue Ridge Cancer Care | Roanoke | Virginia | 24014 | Recruiting |
| Oncology & Hematology Associates of Southwest Virginia Inc dba Blue Ridge Cancer Care | Salem | Virginia | 24153 | Recruiting |
| Virginia Oncology Associates | Virginia Beach | Virginia | 23456 | Recruiting |
| Virginia Oncology Associates | Williamsburg | Virginia | 23188 | Recruiting |
| Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Wytheville | Virginia | 24382 | Recruiting |
| Swedish Cancer Institute | Seattle | Washington | 98104 | Recruiting |
| Swedish Medical Center | Seattle | Washington | 98122 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06966453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06966453 live on ClinicalTrials.gov.