The Vanguard Study: Testing a New Way to Screen for Cancer
Public ClinicalTrials.gov record NCT06995898. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT06995898
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 24,000 participants
Conditions and interventions
Conditions
Interventions
- Biospecimen Collection Procedure
- Device Usage Device
- Electronic Health Record Review Other
- Multi-Cancer Detection Test Procedure
- Questionnaire Administration Other
Procedure · Device · Other
Eligibility (public fields only)
- Age range
- 45 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 15, 2025
- Primary completion
- Dec 30, 2027
- Completion
- Jun 29, 2029
- Last update posted
- Apr 30, 2026
2025 – 2029
United States locations
- U.S. sites
- 37
- U.S. states
- 8
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Permanente-Division of Research | Pleasanton | California | 94588 | Recruiting |
| Keefe Memorial Hospital | Cheyenne Wells | Colorado | 80810 | Recruiting |
| Kaiser Permanente-Franklin | Denver | Colorado | 80205 | Recruiting |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | Recruiting |
| Cancer Care and Hematology-Fort Collins | Fort Collins | Colorado | 80528 | Recruiting |
| UCHealth Greeley Hospital | Greeley | Colorado | 80631 | Recruiting |
| Kaiser Permanente-Rock Creek | Lafayette | Colorado | 80026 | Recruiting |
| Kaiser Permanente-Lone Tree | Lone Tree | Colorado | 80124 | Recruiting |
| Medical Center of the Rockies | Loveland | Colorado | 80538 | Recruiting |
| Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | 96819 | Recruiting |
| Henry Ford Cancer Institute-Downriver | Brownstown | Michigan | 48183 | Recruiting |
| Henry Ford Health Center - Brownstown | Brownstown | Michigan | 48183 | Recruiting |
| Henry Ford Health Center - Chesterfield | Chesterfield | Michigan | 48047 | Recruiting |
| Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan | 48038 | Recruiting |
| Henry Ford Medical Center-Fairlane | Dearborn | Michigan | 48126 | Recruiting |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Recruiting |
| Henry Ford Medical Center - Detroit Northwest | Detroit | Michigan | 48235 | Recruiting |
| Henry Ford Medical Center-Cottage | Grosse Pointe Farms | Michigan | 48236 | Recruiting |
| Henry Ford Medical Center - Livonia | Livonia | Michigan | 48150 | Recruiting |
| Henry Ford Medical Center-Columbus | Novi | Michigan | 48377 | Recruiting |
| Henry Ford Medical Center - Plymouth | Plymouth | Michigan | 48170 | Recruiting |
| Henry Ford Medical Center - Royal Oak | Royal Oak | Michigan | 48067 | Recruiting |
| Henry Ford Medical Center | Sterling Heights | Michigan | 48310 | Recruiting |
| Henry Ford Medical Center - Troy | Troy | Michigan | 48083 | Recruiting |
| Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | 48322 | Recruiting |
| Henry Ford Wyandotte Hospital | Wyandotte | Michigan | 48192 | Recruiting |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | Recruiting |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Sentara Martha Jefferson Hospital | Charlottesville | Virginia | 22911 | Recruiting |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | Recruiting |
| Inova Fair Oaks Hospital | Fairfax | Virginia | 22033 | Recruiting |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | Recruiting |
| VCU Massey Cancer Center at Stony Point | Richmond | Virginia | 23235 | Recruiting |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | Recruiting |
| VCU Community Memorial Health Center | South Hill | Virginia | 23970 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06995898, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 30, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06995898 live on ClinicalTrials.gov.