Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)
Public ClinicalTrials.gov record NCT06999902. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults With Focal Seizures (POWER1)
Study identification
- NCT ID
- NCT06999902
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- Praxis Precision Medicines
- Industry
- Enrollment
- 230 participants
Conditions and interventions
Conditions
Interventions
- 20mg/day PRAX-628 for 6 weeks then 30mg/day PRAX-628 for remaining 6 weeks Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 10, 2024
- Primary completion
- Nov 23, 2025
- Completion
- Dec 7, 2025
- Last update posted
- May 30, 2025
2024 – 2025
United States locations
- U.S. sites
- 16
- U.S. states
- 11
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Praxis Research Site | Phoenix | Arizona | 85032 | Recruiting |
| Praxis Research Site | DeLand | Florida | 32720 | Recruiting |
| Praxis Research Site | Miami Lakes | Florida | 33016 | Recruiting |
| Praxis Research Site | Chicago | Illinois | 60640 | Recruiting |
| Praxis Research Site | Lafayette | Louisiana | 70508 | Recruiting |
| Praxis Research Site | Bethesda | Maryland | 20817 | Recruiting |
| Praxis Research Site | Chesterfield | Missouri | 63005 | Recruiting |
| Praxis Research Site | Ozark | Missouri | 65721 | Recruiting |
| Praxis Research Site | Hackensack | New Jersey | 07601 | Recruiting |
| Praxis Research Site | Middletown | New York | 10940 | Recruiting |
| Praxis Research Site | Canton | Ohio | 44718 | Recruiting |
| Praxis Research Site | Oklahoma City | Oklahoma | 73112 | Recruiting |
| Praxis Research Site | El Paso | Texas | 79912 | Recruiting |
| Praxis Research Site | Frisco | Texas | 75034 | Recruiting |
| Praxis Research Site | Round Rock | Texas | 78681 | Recruiting |
| Praxis Research Site | Seabrook | Texas | 77586 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06999902, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 30, 2025 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06999902 live on ClinicalTrials.gov.