An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)

ClinicalTrials.gov ID: NCT07020819

Public ClinicalTrials.gov record NCT07020819. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 24, 2026, 9:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of a Single Dose of ANX005 in Participants With Guillain-Barré Syndrome

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The goal of this open label study is to measure pharmacokinetics, pharmacodynamics, early efficacy, and safety of tanruprubart in adult and pediatric participants, in the United States, Canada, and Europe.

Study identification

NCT ID: NCT07020819
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Annexon, Inc.; Industry
Enrollment: 30 participants

Conditions and interventions

Conditions

Guillain-Barre Syndrome

Interventions

Tanruprubart Drug

Drug

Eligibility (public fields only)

Age range: 8 Years to 85 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Sep 12, 2025 (Actual)
Primary completion: May 31, 2027 (Estimated)
Completion: Jun 30, 2028 (Estimated)
Last update posted: Oct 19, 2026

2025 – 2028

United States locations

U.S. sites: 20
U.S. states: 14
U.S. cities: 19

Facility	City	State	ZIP	Site status
St. Joseph's Hospital & Medical Center - Barrow Neurological Institute (Dignity Health)	Phoenix	Arizona	85013	Recruiting
HonorHealth Bob Bové Neuroscience Institute	Scottsdale	Arizona	85251	Recruiting
Profound Research LLC	Carlsbad	California	92011	Recruiting
Loma Linda	Loma Linda	California	92354	Recruiting
Children's Hospital of Orange County	Orange	California	92868	Recruiting
University of California Irvine	Orange	California	92868	Recruiting
Stanford University	Palo Alto	California	94304	Recruiting
University of Colorado Hospital	Aurora	Colorado	80045	Recruiting
Georgetown	Washington D.C.	District of Columbia	20007	Recruiting
Mayo Clinic Florida	Jacksonville	Florida	32224	Recruiting
University of Kansas Medical Center	Kansas City	Kansas	66160	Recruiting
Ochsner LSU Health	Shreveport	Louisiana	71101	Recruiting
University Massachusetts Chan Medical School	Worcester	Massachusetts	01655	Recruiting
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Henry Ford Health	Detroit	Michigan	48202	Recruiting
Mayo Rochester	Rochester	Minnesota	55905	Recruiting
Dartmouth Hitchcock Medical Center	Lebanon	New Hampshire	03756	Recruiting
Duke University	Durham	North Carolina	27710	Recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
University of Virginia Department of Neurology	Charlottesville	Virginia	22903	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07020819, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 19, 2026 · Synced Oct 24, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07020819 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →