ClinicalTrials.gov record
Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma
ClinicalTrials.gov ID: NCT07068074
Public ClinicalTrials.gov record NCT07068074. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase III trial compares the effect of wide local excision (WLE) alone to usual care with WLE plus sentinel lymph node (SLN) biopsy for the treatment of older adults with early-stage melanoma. A WLE is a surgical procedure performed to cut out an abnormal lesion and some surrounding normal tissue. This is sometimes followed by a SLN biopsy, in which lymph nodes that tumor cells could spread to are removed as well. Using WLE alone may be just as effective as usual care in treating older adults with early-stage melanoma.
Study identification
- NCT ID
- NCT07068074
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 428 participants
Conditions and interventions
Conditions
Interventions
- Adjuvant Therapy Procedure
- Comprehensive Geriatric Assessment Other
- Computed Tomography Procedure
- Positron Emission Tomography Procedure
- Questionnaire Administration Other
- Sentinel Lymph Node Biopsy Procedure
- Surveillance Behavioral
- Ultrasound Imaging Procedure
- Wide Local Excision Procedure
Procedure · Other · Behavioral
Eligibility (public fields only)
- Age range
- 75 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 17, 2026 (Actual)
- Primary completion
- Jan 1, 2031 (Estimated)
- Completion
- Jan 1, 2031 (Estimated)
- Last update posted
- Sep 24, 2026
2026 – 2031
United States locations
- U.S. sites
- 181
- U.S. states
- 36
- U.S. cities
- 145
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | Recruiting |
| Gulf Health Hospitals Inc/Infirmary Cancer Care - Malbis | Daphne | Alabama | 36526 | Recruiting |
| Thomas Hospital | Fairhope | Alabama | 36532 | Recruiting |
| Mobile Infirmary Medical Center | Mobile | Alabama | 36607 | Recruiting |
| Gulf Health Hospitals Inc/Infirmary Cancer Care - Saraland | Saraland | Alabama | 36571 | Recruiting |
| Fairbanks Memorial Hospital | Fairbanks | Alaska | 99701 | Recruiting |
| Cancer Center at Saint Joseph's | Phoenix | Arizona | 85004 | Recruiting |
| Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande | California | 93420 | Recruiting |
| Mercy Cancer Center - Carmichael | Carmichael | California | 95608 | Recruiting |
| Mercy San Juan Medical Center | Carmichael | California | 95608 | Recruiting |
| Mercy Cancer Center - Elk Grove | Elk Grove | California | 95758 | Recruiting |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care | Irvine | California | 92612 | Recruiting |
| UC San Diego Moores Cancer Center | La Jolla | California | 92093 | Recruiting |
| Veterans Affairs Loma Linda Healthcare System | Loma Linda | California | 92357 | Recruiting |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | Recruiting |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | Recruiting |
| Mercy Cancer Center | Merced | California | 95340 | Recruiting |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | Recruiting |
| Mercy Cancer Center - Rocklin | Rocklin | California | 95765 | Recruiting |
| Mercy Cancer Center - Sacramento | Sacramento | California | 95816 | Recruiting |
| Pacific Central Coast Health Center-San Luis Obispo | San Luis Obispo | California | 93401 | Recruiting |
| Mission Hope Medical Oncology - Santa Maria | Santa Maria | California | 93444 | Recruiting |
| Saint Joseph's Medical Center | Stockton | California | 95204 | Recruiting |
| Woodland Memorial Hospital | Woodland | California | 95695 | Recruiting |
| UCHealth University of Colorado Hospital | Aurora | Colorado | 80045 | Recruiting |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | Recruiting |
| Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | 80907 | Recruiting |
| Saint Francis Cancer Center | Colorado Springs | Colorado | 80923 | Recruiting |
| CommonSpirit Cancer Center Mercy | Durango | Colorado | 81301 | Recruiting |
| Mercy Medical Center | Durango | Colorado | 81301 | Recruiting |
| CommonSpirit Saint Anthony Hospital Cancer Center | Lakewood | Colorado | 80228 | Recruiting |
| Longmont United Hospital | Longmont | Colorado | 80501 | Recruiting |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | Recruiting |
| Saint Anthony North Hospital | Westminster | Colorado | 80023 | Recruiting |
| Beebe Medical Center | Lewes | Delaware | 19958 | Recruiting |
| Beebe South Coastal Health Campus | Millville | Delaware | 19967 | Recruiting |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | Recruiting |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | Recruiting |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | Recruiting |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | Recruiting |
| Christiana Care Health System-Wilmington Hospital | Wilmington | Delaware | 19801 | Recruiting |
| Orlando Health Cancer Institute - Lake Mary | Lake Mary | Florida | 32746 | Recruiting |
| Lakeland Regional Health Hollis Cancer Center | Lakeland | Florida | 33805 | Recruiting |
| Health Central | Ocoee | Florida | 34761 | Recruiting |
| Orlando Health Cancer Institute | Orlando | Florida | 32806 | Recruiting |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | Recruiting |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | Recruiting |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | Recruiting |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | Recruiting |
| Kootenai Clinic Cancer Services - Sandpoint | Sandpoint | Idaho | 83864 | Recruiting |
| Loyola Center for Health at Burr Ridge | Burr Ridge | Illinois | 60527 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| Swedish Covenant Hospital | Chicago | Illinois | 60625 | Recruiting |
| NorthShore University HealthSystem-Evanston Hospital | Evanston | Illinois | 60201 | Recruiting |
| NorthShore University HealthSystem-Glenbrook Hospital | Glenview | Illinois | 60026 | Recruiting |
| NorthShore University HealthSystem-Highland Park Hospital | Highland Park | Illinois | 60035 | Recruiting |
| Loyola Medicine Homer Glen | Homer Glen | Illinois | 60491 | Recruiting |
| Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois | 60045 | Recruiting |
| Loyola University Medical Center | Maywood | Illinois | 60153 | Recruiting |
| Marjorie Weinberg Cancer Center at Loyola-Gottlieb | Melrose Park | Illinois | 60160 | Recruiting |
| Northwestern Medicine Orland Park | Orland Park | Illinois | 60462 | Recruiting |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | Recruiting |
| University of Kansas Cancer Center-Overland Park | Overland Park | Kansas | 66210 | Recruiting |
| University of Kansas Hospital-Indian Creek Campus | Overland Park | Kansas | 66211 | Recruiting |
| University of Kansas Hospital-Westwood Cancer Center | Westwood | Kansas | 66205 | Recruiting |
| CommonSpirit Saint Joseph Hospital - Bardstown | Bardstown | Kentucky | 40004 | Recruiting |
| Commonwealth Cancer Center-Corbin | Corbin | Kentucky | 40701 | Recruiting |
| CommonSpirit Saint Joseph Hospital - Lexington | Lexington | Kentucky | 40504 | Recruiting |
| Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | 40504 | Recruiting |
| CommonSpirit Saint Joseph Medical Center - East Lexington | Lexington | Kentucky | 40509 | Recruiting |
| University of Kentucky/Markey Cancer Center | Lexington | Kentucky | 40536 | Recruiting |
| CommonSpirit Saint Joseph Hospital London | London | Kentucky | 40741 | Recruiting |
| CommonSpirit Saint Joseph Hospital Mount Sterling | Mount Sterling | Kentucky | 40353 | Recruiting |
| LSU Health Baton Rouge-North Clinic | Baton Rouge | Louisiana | 70805 | Recruiting |
| Our Lady of the Lake Physician Group | Baton Rouge | Louisiana | 70808 | Recruiting |
| Christiana Care - Union Hospital | Elkton | Maryland | 21921 | Recruiting |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | Recruiting |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Grand Rapids | Michigan | 49503 | Recruiting |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | Recruiting |
| Trinity Health Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | Suspended |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | Recruiting |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | Recruiting |
| Beacon Kalamazoo Cancer Center | Kalamazoo | Michigan | 49009 | Suspended |
| Beacon Kalamazoo | Kalamazoo | Michigan | 49048 | Suspended |
| Trinity Health Muskegon Hospital | Muskegon | Michigan | 49444 | Suspended |
| Corewell Health Lakeland Hospitals - Niles Hospital | Niles | Michigan | 49120 | Recruiting |
| Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | 49444 | Suspended |
| Corewell Health Reed City Hospital | Reed City | Michigan | 49677 | Recruiting |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | Recruiting |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital | Saint Joseph | Michigan | 49085 | Recruiting |
| Munson Medical Center | Traverse City | Michigan | 49684 | Recruiting |
| University of Michigan Health - West | Wyoming | Michigan | 49519 | Recruiting |
| Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | 56601 | Recruiting |
| Sanford Thief River Falls Medical Center | Thief River Falls | Minnesota | 56701 | Recruiting |
| University of Kansas Cancer Center - Briarcliff | Kansas City | Missouri | 64116 | Recruiting |
| University of Kansas Cancer Center - North | Kansas City | Missouri | 64154 | Recruiting |
| University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri | 64064 | Recruiting |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | Recruiting |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | Recruiting |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | Recruiting |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | Recruiting |
| Great Falls Clinic | Great Falls | Montana | 59405 | Recruiting |
| Hi-Line Sletten Cancer Center | Havre | Montana | 59501 | Recruiting |
| Benefis Helena Specialty Center | Helena | Montana | 59601 | Recruiting |
| Logan Health Medical Center | Kalispell | Montana | 59901 | Recruiting |
| Community Medical Center | Missoula | Montana | 59804 | Recruiting |
| CHI Health Saint Francis | Grand Island | Nebraska | 68803 | Recruiting |
| CHI Health Good Samaritan | Kearney | Nebraska | 68847 | Recruiting |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | Recruiting |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | Recruiting |
| Alegent Health Lakeside Hospital | Omaha | Nebraska | 68130 | Recruiting |
| Renown Regional Medical Center | Reno | Nevada | 89502 | Recruiting |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | Recruiting |
| Hackettstown Medical Center | Hackettstown | New Jersey | 07840 | Recruiting |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | Recruiting |
| Morristown Medical Center | Morristown | New Jersey | 07960 | Recruiting |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | Recruiting |
| Newton Medical Center | Newton | New Jersey | 07860 | Recruiting |
| John Theurer Cancer Center at From Road | Paramus | New Jersey | 07652 | Recruiting |
| Chilton Medical Center | Pompton | New Jersey | 07444 | Recruiting |
| Overlook Hospital | Summit | New Jersey | 07902 | Recruiting |
| Community Medical Center | Toms River | New Jersey | 08755 | Recruiting |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | Recruiting |
| Lovelace Women's Hospital | Albuquerque | New Mexico | 87109 | Recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Recruiting |
| Glens Falls Hospital | Glens Falls | New York | 12801 | Recruiting |
| NYU Langone Hospital - Long Island | Mineola | New York | 11501 | Recruiting |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | Recruiting |
| NYU Langone Hospital - Suffolk | Patchogue | New York | 11772 | Recruiting |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | Recruiting |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | Recruiting |
| Duke Cancer Center Cary | Cary | North Carolina | 27518 | Recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Recruiting |
| Duke Cancer Center Raleigh | Raleigh | North Carolina | 27609 | Recruiting |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | Recruiting |
| Sanford South University Medical Center | Fargo | North Dakota | 58103 | Recruiting |
| Southpointe-Sanford Medical Center Fargo | Fargo | North Dakota | 58103 | Recruiting |
| Sanford Medical Center Fargo | Fargo | North Dakota | 58104 | Recruiting |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | Recruiting |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | Recruiting |
| UH Seidman Cancer Center at UH Avon Health Center | Avon | Ohio | 44011 | Recruiting |
| UHHS-Chagrin Highlands Medical Center | Beachwood | Ohio | 44122 | Recruiting |
| Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | 45220 | Recruiting |
| Bethesda North Hospital | Cincinnati | Ohio | 45242 | Recruiting |
| TriHealth Cancer Institute-Westside | Cincinnati | Ohio | 45247 | Recruiting |
| TriHealth Cancer Institute-Anderson | Cincinnati | Ohio | 45255 | Recruiting |
| Case Western Reserve University | Cleveland | Ohio | 44106 | Recruiting |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | Recruiting |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Christiana Care Health System-Concord Health Center | Chadds Ford | Pennsylvania | 19317 | Recruiting |
| Fox Chase Cancer Center - East Norriton Hospital Outpatient Center | East Norriton | Pennsylvania | 19401 | Recruiting |
| UPMC Hillman Cancer Center Erie | Erie | Pennsylvania | 16505 | Recruiting |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | Recruiting |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Asplundh Cancer Pavilion | Willow Grove | Pennsylvania | 19090 | Recruiting |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Recruiting |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | Recruiting |
| Central Vermont Medical Center/National Life Cancer Treatment | Berlin Corners | Vermont | 05602 | Recruiting |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | Recruiting |
| University of Vermont and State Agricultural College | Burlington | Vermont | 05405 | Recruiting |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | Recruiting |
| VCU Massey Cancer Center at Stony Point | Richmond | Virginia | 23235 | Recruiting |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
| University of Washington Medical Center - Montlake | Seattle | Washington | 98195 | Recruiting |
| Saint Joseph Medical Center Hematology and Oncology - Silverdale | Silverdale | Washington | 98383 | Recruiting |
| United Hospital Center | Bridgeport | West Virginia | 26330 | Recruiting |
| WVUH-Berkely Medical Center | Martinsburg | West Virginia | 25401 | Recruiting |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | Recruiting |
| Camden Clark Medical Center | Parkersburg | West Virginia | 26101 | Recruiting |
| Princeton Community Hospital | Princeton | West Virginia | 24740 | Recruiting |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | Recruiting |
| Froedtert Menomonee Falls Hospital | Menomonee Falls | Wisconsin | 53051 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
| Froedtert and MCW Moorland Reserve Health Center | New Berlin | Wisconsin | 53151 | Recruiting |
| Drexel Town Square Health Center | Oak Creek | Wisconsin | 53154 | Recruiting |
| Froedtert West Bend Hospital/Kraemer Cancer Center | West Bend | Wisconsin | 53095 | Recruiting |
| Marshfield Medical Center - Weston | Weston | Wisconsin | 54476 | Recruiting |
| Memorial Hospital of Laramie County | Cheyenne | Wyoming | 82001 | Recruiting |
| Billings Clinic-Cody | Cody | Wyoming | 82414 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07068074, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 24, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07068074 live on ClinicalTrials.gov.