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Active, not recruiting Phase 2 Interventional

A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis

ClinicalTrials.gov ID: NCT07105488

Public ClinicalTrials.gov record NCT07105488. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 28, 2026, 11:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Parallel-arm, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Efficacy and Safety of BFB759 in Patients With Atopic Dermatitis (COMPASS 2-AD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a double-blind, placebo-controlled study where subjects are participating for approximately 36 to 40 weeks. The study compares how well BFB759 works and how safe it is compared with a placebo.

Study identification

NCT ID
NCT07105488
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Bluefin Biomedicine, Inc.
Industry
Enrollment
225 participants

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 14, 2025
Primary completion
Feb 27, 2027
Completion
Mar 30, 2027
Last update posted
Jul 29, 2026

2025 – 2027

United States locations

U.S. sites
48
U.S. states
20
U.S. cities
43
Facility City State ZIP Site status
Mountain West Derm - Blackhart PLLC dba Skin Cancer and Dermatology Institute Phoenix Arizona 85008 —
Skin Cancer and Dermatology Institute Phoenix Arizona 85008 —
T. Joseph Raoof Md, Inc Encino California 91436 —
Marvel Clinical Research Huntington Beach California 92647 —
Antelope Valley Clinical Trials Lancaster California 93534 —
Probity Medical Research Los Angeles California 90017 —
NorCal Clinical Research Rocklin California 95765 —
Focus Clinical Research, LLC -S West Hills California 91307 —
Skin Care Research Boca Raton Florida 33486 —
Florida Academic Dermatology Center Res and Edu, LLC Coral Gables Florida 33134 —
Center for Skin Science and Innovation Fort Lauderdale Florida 33308 —
Gsi Clinical Research Margate Florida 33063 —
Ziaderm Research LLC North Miami Beach Florida 33162 —
Lenus Research & Medical Group, LLC Sweetwater Florida 33172 —
Clinical Trials Management - S Tampa Florida 33607 —
Conquest Research LLC Winter Park Florida 32789 —
Skin Cancer and Dermatology Institute Douglasville Georgia 30135 —
Southeast Research Specialists, LLC Douglasville Georgia 30135 —
The Indiana Clinical Trials Center Plainfield Indiana 46168 —
Clinical Trials Management - S Covington Louisiana 70433 —
Clinical Trials Management, LLC Metairie Louisiana 70006 —
MetroBoston Clinical Partners Brighton Massachusetts 02135 —
Oakland Hills Dermatology Auburn Hills Michigan 48326 —
MI Skin Innovations Northville Michigan 48167 —
Medisearch, LLC Saint Joseph Missouri 64506 —
Elias Research Associates Missoula Montana 59808 —
JDR Dermatology Research Las Vegas Nevada 89145 —
Mountain West Derm - Blackhart PLLC dba Skin Cancer and Dermatology Institute Reno Nevada 89509 —
Skin Cancer and Dermatology Institute Reno Nevada 89509 —
Mountain West Derm - Blackhart PLLC dba Skin Cancer and Dermatology Institute Sparks Nevada 89436 —
Skin Cancer and Dermatology Institute Sparks Nevada 89436 —
Schweiger Dermatology, PC R.D. Hackensack New Jersey 07601 —
Bobby Buka, MD (The Dermatology Specialist) New York New York 10012 —
Bobby Buka, MD New York New York 10012 —
Equity Medical, LLC The Bronx New York 10455 —
Vitality Clinical Trials LLC Woodbury New York 11797 —
DJL Clinical Research Charlotte North Carolina 28277 —
Optima Research-Boardman Boardman Ohio 44512 —
Apex Clinical Research Center, LLC Canton Ohio 44718 —
Apex Clinical Research Center, LLC Mayfield Heights Ohio 44124 —
UPMC Pittsburgh Pennsylvania 15213 —
International Clinical Research - Tennesee, LLC Murfreesboro Tennessee 37130 —
Dermatology Treatment & Research Center Dallas Texas 75230 —
Stride Clinical Research Missouri City Texas 77459 —
Progressive Clinical Research San Antonio Texas 78213 —
Stryde Research-Epiphany Dermatology Southlake Texas 76092 —
Virginia Dermatology & Skin Cancer Center Norfolk Virginia 23502 —
DBA Dermatology of Seattle & Bellevue -S Burien Washington 98618 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07105488, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 29, 2026 · Synced Sep 28, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07105488 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →