Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

ClinicalTrials.gov ID: NCT07116967

Public ClinicalTrials.gov record NCT07116967. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 8:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3b/4 Multi-center, Randomized, Open-label, Long-term Safety Study of Deucravacitinib in Comparison to Ustekinumab in Participants With Moderate-to-Severe Plaque Psoriasis

Study identification

NCT ID: NCT07116967
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Bristol-Myers Squibb; Industry
Enrollment: 3,040 participants

Conditions and interventions

Conditions

Plaque Psoriasis

Interventions

Deucravacitinib Drug
Ustekinumab Drug

Drug

Eligibility (public fields only)

Age range: 40 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Sep 21, 2025
Primary completion: Jan 15, 2031
Completion: Jan 15, 2031
Last update posted: May 6, 2026

2025 – 2031

United States locations

U.S. sites: 122
U.S. states: 33
U.S. cities: 104

Facility	City	State	ZIP	Site status
Local Institution - 0088	Birmingham	Alabama	35249	Not yet recruiting
Medical Dermatology Specialists - Phoenix	Phoenix	Arizona	85006-2722	Recruiting
Saguaro Dermatology - Phoenix	Phoenix	Arizona	85008	Recruiting
Omni Dermatology	Phoenix	Arizona	85018	Recruiting
Alliance Dermatology	Phoenix	Arizona	85032	Recruiting
Local Institution - 0322	Scottsdale	Arizona	85254	Withdrawn
Local Institution - 0188	Scottsdale	Arizona	85255	Withdrawn
Scottsdale Clinical Trials	Scottsdale	Arizona	85260	Recruiting
Omni Dermatology	Tempe	Arizona	85282	Recruiting
Clinical Trials Institute of Northwest Arkansas	Fayetteville	Arkansas	72703-6245	Recruiting
Northwest Arkansas Clinical Trials Center (NWACTC), PLLC	Rogers	Arkansas	72758	Recruiting
California Dermatology & Clinical Research Institute	Encinitas	California	92024-7700	Recruiting
T. Joseph Raoof MD Inc	Encino	California	91436	Recruiting
First OC Dermatology - Fountain Valley	Fountain Valley	California	92708	Recruiting
Center For Dermatology Clinical Research, Inc.	Fremont	California	94538	Recruiting
Marvel Clinical Research	Huntington Beach	California	92647	Recruiting
Dermatology Research Associates - Howard Sofen, MD	Los Angeles	California	90045	Recruiting
Local Institution - 0192	Los Angeles	California	90056-1660	Not yet recruiting
Northridge Clinical Trials - Elite Clinical Network	Northridge	California	91325	Recruiting
Cura Clinical Research - Palmdale	Palmdale	California	93551	Recruiting
Pasadena Clinical Trials	Pasadena	California	91101	Recruiting
Empire Clinical Research - Pomona	Pomona	California	91767	Recruiting
Integrative Skin Science and Research	Sacramento	California	95815	Recruiting
UC Davis Dermatology Clinic	Sacramento	California	95816	Recruiting
Local Institution - 0078	San Diego	California	92123-1523	Withdrawn
Cura Clinical Research - Santa Clarita	Santa Clarita	California	91355	Recruiting
Clinical Science Institute	Santa Monica	California	90404	Recruiting
Advanced Dermatology and Skin Cancer Institute - Beverly Hills	Sherman Oaks	California	91403	Recruiting
Unison Clinical Trials	Sherman Oaks	California	91403	Recruiting
Golden State Dermatology - Ygnacio Valley Road	Walnut Creek	California	94598-3335	Recruiting
Local Institution - 0494	Castle Rock	Colorado	80109	Not yet recruiting
Local Institution - 0334	Washington D.C.	District of Columbia	20746	Withdrawn
Skin Care Research LLC (SCR) - Boca Raton	Boca Raton	Florida	33486	Recruiting
Driven Research LLC	Coral Gables	Florida	33134	Recruiting
Florida Academic Dermatology Center	Coral Gables	Florida	33134	Recruiting
Accel Research Sites - Maitland Clinical Research Unit	Maitland	Florida	32751	Recruiting
Miami Dermatology and Laser Research	Miami	Florida	33133	Recruiting
International GCC Research	Miami	Florida	33135	Recruiting
BioResearch Partner (BRP) - Miami	Miami	Florida	33155	Recruiting
Local Institution - 0029	Miami Lakes	Florida	33014	Withdrawn
Renstar Medical Research	Ocala	Florida	34471	Recruiting
LENUS Research	Sweetwater	Florida	33172	Recruiting
Local Institution - 0089	Tampa	Florida	33615	Withdrawn
Hamilton Dermatology (Atlanta Dermatology, Vein & Research Center, LLC)	Alpharetta	Georgia	30022	Recruiting
Local Institution - 0434	Atlanta	Georgia	30305	Completed
Velocity Clinical Research, Savannah	Savannah	Georgia	31406	Recruiting
Local Institution - 0395	Chicago	Illinois	60614	Not yet recruiting
Endeavor Health Clinical Trials	Skokie	Illinois	60077	Recruiting
Deaconess Clinic Downtown	Evansville	Indiana	47708	Recruiting
Dawes Fretzin Clinical Research Group, LLC	Indianapolis	Indiana	46250	Recruiting
Southern Indiana Clinical trials	New Albany	Indiana	47150	Recruiting
Equity Medical - Bowling Green	Bowling Green	Kentucky	42104	Recruiting
Physician Skin Care, PLLC	Louisville	Kentucky	40217	Recruiting
Local Institution - 0030	Owensboro	Kentucky	42301	Withdrawn
Clinical Trials Management, LLC - Northshore Office	Covington	Louisiana	70433	Recruiting
Shondra L. Smith, MD - Dermatology and Advanced Aesthetics	Lake Charles	Louisiana	70605	Recruiting
Clinical Trials Management	Metairie	Louisiana	70006	Recruiting
Local Institution - 0069	New Orleans	Louisiana	70112	Not yet recruiting
Lawrence J. Green, MD. LLC	Rockville	Maryland	20850	Recruiting
U.S. Dermatology Partners Rockville	Rockville	Maryland	20850	Recruiting
Metro Boston Clinical Partners	Brighton	Massachusetts	02135	Recruiting
Kuchnir Dermatology & Dermatologic Surgery	Milford	Massachusetts	01757	Recruiting
Local Institution - 0287	Quincy	Massachusetts	02169-4339	Withdrawn
Oakland Hills Dermatology	Auburn Hills	Michigan	48326-3396	Recruiting
Michigan Center for Skin Care Research	Clinton Township	Michigan	48038-1137	Recruiting
Somerset Skin Centre	Troy	Michigan	48084-5260	Recruiting
Michigan Dermatology Institute - Waterford	Waterford	Michigan	48328-3277	Recruiting
Minnesota Clinical Study Center (MCSC)	New Brighton	Minnesota	55112	Recruiting
Local Institution - 0433	Columbia	Missouri	65201-6625	Not yet recruiting
Saint Louis University	St Louis	Missouri	63110	Recruiting
Local Institution - 0397	Omaha	Nebraska	68114-2508	Withdrawn
Local Institution - 0454	Las Vegas	Nevada	89145	Withdrawn
Las Vegas Clinical Trials, LLC	North Las Vegas	Nevada	89030-7193	Recruiting
Local Institution - 0097	Portsmouth	New Hampshire	03801	Not yet recruiting
StracSkin	Portsmouth	New Hampshire	03801	Recruiting
Local Institution - 0079	Teaneck	New Jersey	07666	Withdrawn
Local Institution - 0359	Verona	New Jersey	07044	Completed
Forest Hills Dermatology Group	Kew Gardens	New York	11415	Recruiting
The Skin Center Dermatology Group	New City	New York	10956-7153	Recruiting
Local Institution - 0410	New York	New York	10029-6574	Withdrawn
Skin Search Rochester	Rochester	New York	14623-1507	Recruiting
Elyse S. Rafal, MD PC - Rafal Center for Dermatology & Cosmetic Surgery	Stony Brook	New York	11790-2598	Recruiting
Equity Medical - New York	The Bronx	New York	10455	Recruiting
Accellacare - Cary	Cary	North Carolina	27518	Recruiting
Local Institution - 0332	Chapel Hill	North Carolina	27516	Not yet recruiting
Local Institution - 0165	Chapel Hill	North Carolina	27517	Withdrawn
Local Institution - 0406	Hickory	North Carolina	28602	Completed
Wilmington Dermatology Center-WDC Cosmetic and Research	Wilmington	North Carolina	28405	Recruiting
Local Institution - 0177	Bexley	Ohio	43209-2421	Withdrawn
Local Institution - 0392	Canal Winchester	Ohio	43110-2069	Withdrawn
Apex Clinical Research Center - Canton	Canton	Ohio	44718	Recruiting
Wright State Physicians	Fairborn	Ohio	45324	Recruiting
Dermatologists of Southwest Ohio	Mason	Ohio	45040	Recruiting
Apex Clinical Research Center	Mayfield Heights	Ohio	44124	Recruiting
Dermatology Partners Inc. - Medina Clinical Research	Medina	Ohio	44256-9312	Recruiting
Unity Clinical Research (UCR)	Oklahoma City	Oklahoma	73118-2864	Recruiting
Central Sooner Research (CSR) - Oklahoma City	Oklahoma City	Oklahoma	73170	Recruiting
Velocity Clinical Research, Medford	Medford	Oregon	97504	Recruiting
Oregon Medical Research Center	Portland	Oregon	97201	Recruiting
Oregon Dermatology and Research Center	Portland	Oregon	97210	Recruiting
Best Skin Research	Camp Hill	Pennsylvania	17011-2308	Recruiting
Local Institution - 0131	Exton	Pennsylvania	19341	Withdrawn
UPMC Department of Dermatology	Pittsburgh	Pennsylvania	15213	Recruiting
Palmetto Clinical Trial Services - Administrative Office	Anderson	South Carolina	29621	Recruiting
Local Institution - 0422	Greenville	South Carolina	29615	Withdrawn
Palmetto Clinical Trial Services - Administrative Office	Greenville	South Carolina	29615	Recruiting
Local Institution - 0418	North Charleston	South Carolina	29405	Withdrawn
Local Institution - 0084	Rapid City	South Dakota	57702-9208	Not yet recruiting
Local Institution - 0407	Goodlettsville	Tennessee	37072-2301	Completed
Local Institution - 0338	Hermitage	Tennessee	37076	Completed
International Clinical Research (IC Research) - Murfreesboro	Murfreesboro	Tennessee	37130	Recruiting
Local Institution - 0408	Nashville	Tennessee	37205	Completed
Arlington Center for Dermatology	Arlington	Texas	76011	Recruiting
Studies in Dermatology, LLC	Cypress	Texas	77429	Recruiting
Modern Research Associates, PLLC	Dallas	Texas	75231	Recruiting
Local Institution - 0468	Dallas	Texas	75390	Not yet recruiting
Local Institution - 0500	Houston	Texas	77065	Not yet recruiting
Texas Dermatology and Laser Specialists	San Antonio	Texas	78218	Recruiting
Center For Clinical Studies	Webster	Texas	77598	Recruiting
Local Institution - 0333	Norfolk	Virginia	23502	Withdrawn
Frontier Dermatology	Mill Creek	Washington	98012	Recruiting
Premier Clinical Research	Spokane	Washington	99202	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 235 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07116967, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 6, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07116967 live on ClinicalTrials.gov.

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