Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma
Public ClinicalTrials.gov record NCT07120503. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Double-blind Placebo-Controlled Study to Evaluate the Pharmacokinetics, Immunogenicity, Safety and Efficacy of WIN378 in Adult Participants With Moderate or Severe Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate or severe asthma. WIN378 blocks the action of a protein called TSLP which causes inflammation in the lung and may contribute to your asthma control and symptoms. The study will test how doses of WIN378 are handled by your body (pharmacokinetics) and assess the safety of the medicine and will assess markers of asthma inflammation in your breath and in your blood, lung function and asthma control (pharmacodynamics).
Study identification
- NCT ID
- NCT07120503
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 136 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 23, 2025
- Primary completion
- Jun 30, 2027
- Completion
- Sep 30, 2027
- Last update posted
- Apr 6, 2026
2025 – 2027
United States locations
- U.S. sites
- 21
- U.S. states
- 14
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| WB Contracted Clinical Research Site | Los Angeles | California | 90025-7014 | — |
| WB Contracted Clinical Research Site | San Jose | California | 95117 | — |
| WB Contracted Clinical Research Site | Melbourne | Florida | 32763 | — |
| WB Contracted Clinical Research Site | Miami | Florida | 33175 | — |
| WB Contracted Clinical Research Site | White Marsh | Maryland | 21162 | — |
| WB Contracted Clinical Research Site | Stow | Massachusetts | 01775-1205 | — |
| WB Contracted Clinical Research Site | Detroit | Michigan | 48202-2608 | — |
| WB Contracted Clinical Research Site | Richfield | Minnesota | 55423-2477 | — |
| WB Contracted Clinical Research Site | St Louis | Missouri | 98119 | — |
| WB Contracted Clinical Research Site | Bellevue | Nebraska | 68123 | — |
| WB Contracted Clinical Research Site | Toledo | Ohio | 43560 | — |
| WB Contracted Clinical Research Site | Edmond | Oklahoma | 73034 | — |
| WB Contracted Clinical Research Site | Pittsburgh | Pennsylvania | 15213-3236 | — |
| WB Contracted Clinical Research Site | Charleston | South Carolina | 29420 | — |
| WB Contracted Clinical Research Site | Spartanburg | South Carolina | 29303 | — |
| WB Contracted Clinical Research Site | Austin | Texas | 78730 | — |
| WB Contracted Clinical Research Site | El Paso | Texas | 79903 | — |
| WB Contracted Clinical Research Site | McKinney | Texas | 75069-8085 | — |
| WB Contracted Clinical Research Site | San Antonio | Texas | 78229 | — |
| WB Contracted Clinical Research Site | Tyler | Texas | 75708-3154 | — |
| WB Contracted Clinical Research Site | Richmond | Virginia | 23226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07120503, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 6, 2026 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07120503 live on ClinicalTrials.gov.