ClinicalTrials.gov record
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
ClinicalTrials.gov ID: NCT07144280
Public ClinicalTrials.gov record NCT07144280. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 4, 2026, 11:40 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PADL1NK-005: A Randomized, Phase 3, Open-Label Study to Evaluate PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Study identification
- NCT ID
- NCT07144280
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 680 participants
Conditions and interventions
Conditions
Interventions
- Docetaxel monotherapy Drug
- PF-08046054 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 28, 2025
- Primary completion
- Mar 9, 2028
- Completion
- Mar 9, 2032
- Last update posted
- Apr 20, 2026
2025 – 2032
United States locations
- U.S. sites
- 133
- U.S. states
- 25
- U.S. cities
- 101
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Oncology | Alabaster | Alabama | 35007 | Recruiting |
| Alabama Oncology | Bessemer | Alabama | 35022 | Recruiting |
| Alabama Oncology, Bruno Cancer Center | Birmingham | Alabama | 35205 | Recruiting |
| Alabama Oncology | Birmingham | Alabama | 35209 | Recruiting |
| Alabama Oncology | Birmingham | Alabama | 35211 | Recruiting |
| Alabama Oncology | Birmingham | Alabama | 35235 | Recruiting |
| Alabama Oncology | Birmingham | Alabama | 35243 | Recruiting |
| Southern Cancer Center | Daphne | Alabama | 36526 | Recruiting |
| Southern Cancer Center, PC | Foley | Alabama | 36535 | Recruiting |
| Alaska Oncology and Hematology | Anchorage | Alaska | 99508 | Recruiting |
| Highlands Oncology Group, PA | Fayetteville | Arkansas | 72703 | Not yet recruiting |
| Highlands Oncology Group, PA | Rogers | Arkansas | 72758 | Not yet recruiting |
| Highlands Oncology Group, PA | Springdale | Arkansas | 72762 | Not yet recruiting |
| Highlands Oncology Group | Springdale | Arkansas | 72762 | Not yet recruiting |
| Providence Medical Foundation | Fullerton | California | 92835 | Not yet recruiting |
| Providence St. Jude Medical Center | Fullerton | California | 92835 | Not yet recruiting |
| Rocky Mountain Cancer Centers,LLP | Denver | Colorado | 80218 | Recruiting |
| Medical Oncology Hematology Consultants, PA | Newark | Delaware | 19713 | Not yet recruiting |
| Cancer Care Centers of Brevard, Inc. | Palm Bay | Florida | 32901 | Recruiting |
| Florida Cancer Affiliates - Panama City | Panama City | Florida | 32405 | Recruiting |
| Tennessee Oncology, PLLC - Dalton | Dalton | Georgia | 30720 | Not yet recruiting |
| Tennessee Oncology, PLLC - Ringgold | Ringgold | Georgia | 30736 | Not yet recruiting |
| Illinois Cancer Specialists | Arlington Heights | Illinois | 60005 | Not yet recruiting |
| Illinois CancerCare- Bloomington | Bloomington | Illinois | 61704 | Recruiting |
| Illinois Cancer Specialists | Chicago | Illinois | 60631 | Not yet recruiting |
| Illinois CancerCare Galesburg | Galesburg | Illinois | 61401 | Recruiting |
| Accellacare of Duly | Lisle | Illinois | 60532 | Recruiting |
| Illinois CancerCare-Ottawa-Fox River Cancer Center | Ottawa | Illinois | 61350 | Recruiting |
| Illinois CancerCare- Pekin | Pekin | Illinois | 61554 | Recruiting |
| Illinois Cancer Care | Peoria | Illinois | 61615 | Recruiting |
| Illinois CancerCare-Peru - Valley Regional Cancer Center | Peru | Illinois | 61354 | Recruiting |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | Recruiting |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | Not yet recruiting |
| Maryland Oncology Hematology, P.A. | Annapolis | Maryland | 21401 | Not yet recruiting |
| Maryland Oncology Hematology, P.A. | Bethesda | Maryland | 20817 | Not yet recruiting |
| Maryland Oncology Hematology, PA | Brandywine | Maryland | 20613 | Not yet recruiting |
| Maryland Oncology Hematology | Columbia | Maryland | 21044 | Not yet recruiting |
| Maryland Oncology Hematology P.A. | Germantown | Maryland | 20876 | Not yet recruiting |
| Maryland Oncology Hematology, P.A | Largo | Maryland | 20774 | Not yet recruiting |
| Maryland Oncology Hematology PA | Rockville | Maryland | 20850 | Not yet recruiting |
| Maryland Oncology Hematology, P.A. | Silver Spring | Maryland | 20904 | Not yet recruiting |
| Minnesota Oncology Hematology, PA | Burnsville | Minnesota | 55337 | Recruiting |
| Allina Health Cancer Institute - Mercy Hospital | Coon Rapids | Minnesota | 55433 | Recruiting |
| Minnesota Oncology Hematology, PA | Coon Rapids | Minnesota | 55433 | Recruiting |
| Minnesota Oncology Hematology, P.A. | Edina | Minnesota | 55435 | Recruiting |
| Minnesota Oncology Hematology PA | Maple Grove | Minnesota | 55369 | Recruiting |
| Minnesota Oncology Hematology, P.A. | Maplewood | Minnesota | 55109 | Recruiting |
| Minnesota Oncology Hematology, P.A... | Minneapolis | Minnesota | 55404 | Recruiting |
| Allina Health Cancer Institute - Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | Recruiting |
| Allina Health Cancer Institute - United Hospital | Saint Paul | Minnesota | 55102 | Recruiting |
| Minnesota Oncology Hematology, PA | Woodbury | Minnesota | 55125 | Recruiting |
| Missouri Cancer Associates | Columbia | Missouri | 65201 | Recruiting |
| Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana | Billings | Montana | 59102 | Not yet recruiting |
| Nebraska Medicine-Bellevue Medical Center | Bellevue | Nebraska | 68123 | Not yet recruiting |
| Nebraska Medicine | Omaha | Nebraska | 68105 | Not yet recruiting |
| Nebraska Medicine - Village Pointe | Omaha | Nebraska | 68118 | Not yet recruiting |
| University Of Nebraska Medical Center | Omaha | Nebraska | 68198 | Not yet recruiting |
| Essex Oncology of North Jersey | Belleville | New Jersey | 07109 | Not yet recruiting |
| CHRISTUS St. Vincent Regional Cancer Center | Santa Fe | New Mexico | 87505 | Not yet recruiting |
| Christus St. Vincent Regional Medical Center | Santa Fe | New Mexico | 87505 | Not yet recruiting |
| Montefiore Medical Center - Montefiore Medical Park | The Bronx | New York | 10461 | Recruiting |
| White Plains Hospital | White Plains | New York | 10601 | Recruiting |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45211 | Recruiting |
| Oncology Hematology Care | Cincinnati | Ohio | 45242 | Recruiting |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45245 | Recruiting |
| Oncology Hematology Care Inc | Fairfield | Ohio | 45014 | Recruiting |
| Oncology Associates of Oregon, P.C. | Eugene | Oregon | 97401 | Recruiting |
| Alliance Cancer Specialists, PC | Bensalem | Pennsylvania | 19020 | Recruiting |
| Consultants in Medical Oncology and Hematology, P.C. | Broomall | Pennsylvania | 19008 | Recruiting |
| Alliance Cancer Specialists, PC | Doylestown | Pennsylvania | 18901 | Recruiting |
| Alliance Cancer Specialists, PC | Horsham | Pennsylvania | 19044 | Recruiting |
| Alliance Cancer Specialists, P.C. | Langhorne | Pennsylvania | 19047 | Recruiting |
| Alliance Cancer Specialists, PC | Media | Pennsylvania | 19063 | Recruiting |
| Alliance Cancer Specialists, PC | Sellersville | Pennsylvania | 18960 | Recruiting |
| Alliance Cancer Specialists, PC | Wynnewood | Pennsylvania | 19096 | Recruiting |
| Tennessee Oncology, PLLC - Chattanooga Downtown | Chattanooga | Tennessee | 37403 | Not yet recruiting |
| Tennessee Oncology, PLLC - Chattanooga Med Park II | Chattanooga | Tennessee | 37404 | Not yet recruiting |
| Tennessee Oncology, PLLC - Chattanooga Memorial | Chattanooga | Tennessee | 37404 | Not yet recruiting |
| Tennessee Oncology, PLLC - Investigational Drug Services/Supply Storage | Chattanooga | Tennessee | 37404 | Not yet recruiting |
| Tennessee Oncology, PLLC - Cleveland | Cleveland | Tennessee | 37311 | Not yet recruiting |
| Tennessee Cancer Specialists | Knoxville | Tennessee | 37909 | Recruiting |
| Tennessee Oncology, PLLC - Lebanon | Lebanon | Tennessee | 37090 | Not yet recruiting |
| Tennessee Oncology, PLLC - Mount Juliet | Mount Juliet | Tennessee | 37122 | Not yet recruiting |
| Tennessee Oncology, PLLC - Murfreesboro | Murfreesboro | Tennessee | 37129 | Not yet recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Not yet recruiting |
| Tennessee Oncology, PLLC - Investigational Drug Services | Nashville | Tennessee | 37203 | Not yet recruiting |
| Tennessee Oncology, PLLC - Nashville Elliston Place Plaza Medical Oncology & Hematology Clinic | Nashville | Tennessee | 37203 | Not yet recruiting |
| Tennessee Oncology, PLLC - Nashville Saint Thomas West | Nashville | Tennessee | 37205 | Not yet recruiting |
| Tennessee Oncology, PLLC - Shelbyville | Shelbyville | Tennessee | 37160 | Not yet recruiting |
| Tennessee Oncology, PLLC - Smyrna | Smyrna | Tennessee | 37167 | Not yet recruiting |
| Texas Oncology - West Texas | Abilene | Texas | 79606 | Recruiting |
| Texas Oncology-Northeast Texas | Allen | Texas | 75013 | Recruiting |
| Texas Oncology- Central South. | Austin | Texas | 78705 | Recruiting |
| Texas Oncology Central South | Austin | Texas | 78731 | Recruiting |
| Texas Oncology- Central South. | Austin | Texas | 78745 | Recruiting |
| Texas Oncology - Central South (Renfert Way) | Austin | Texas | 78758 | Recruiting |
| Texas Oncology - Gulf Coast | Beaumont | Texas | 77702 | Recruiting |
| The University of Texas, MD Anderson Cancer Center - Woodlands | Conroe | Texas | 77384 | Recruiting |
| Texas Oncology - Dallas (Sammons) | Dallas | Texas | 75246 | Recruiting |
| Texas Oncology-Northeast Texas | Denison | Texas | 75020 | Recruiting |
| Texas Oncology-Northeast Texas | Denton | Texas | 76201 | Recruiting |
| Texas Oncology-Northeast Texas | Flower Mound | Texas | 75028 | Recruiting |
| Texas Oncology- Central South | Harlingen | Texas | 78550 | Recruiting |
| The University of Texas MD Anderson Cancer Center Diagnostic Imaging | Houston | Texas | 77030 | Recruiting |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| The University of Texas, MD Anderson Cancer Center- Interventional Radiology | Houston | Texas | 77030 | Recruiting |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| The University of Texas MD Anderson Cancer Center Clinical Research Imaging | Houston | Texas | 77054 | Recruiting |
| The University of Texas, MD Anderson Cancer Center - West Houston | Houston | Texas | 77079 | Recruiting |
| US Oncology Investigational Product Center (IPC) | Irving | Texas | 75063 | Recruiting |
| US Oncology Investigational Products Center (IPC) | Irving | Texas | 75063 | Recruiting |
| US Oncology Investigational Products Center(IPC) | Irving | Texas | 75063 | Recruiting |
| The University of Texas, MD Anderson Cancer Center - League City | League City | Texas | 77573 | Recruiting |
| Texas Oncology-Northeast Texas | Lewisville | Texas | 75056 | Recruiting |
| Texas Oncology-Northeast Texas | Longview | Texas | 75601 | Recruiting |
| Texas Oncology | McAllen | Texas | 78503 | Recruiting |
| Texas Oncology-Northeast Texas | McKinney | Texas | 75071 | Recruiting |
| Texas Oncology-Northeast Texas | Palestine | Texas | 75801 | Recruiting |
| Texas Oncology-Northeast Texas | Paris | Texas | 75460 | Recruiting |
| Texas Oncology - Gulf Coast | Pearland | Texas | 77584 | Recruiting |
| Baylor Scott & White Health - Round Rock | Round Rock | Texas | 78665 | Not yet recruiting |
| The University of Texas, MD Anderson Cancer Center - Sugar Land | Sugar Land | Texas | 77478 | Recruiting |
| Texas Oncology - Gulf Coast | Sugar Land | Texas | 77479 | Recruiting |
| Texas Oncology - Gulf Coast | The Woodlands | Texas | 77380 | Recruiting |
| Texas Oncology-Northeast Texas | Tyler | Texas | 75702 | Recruiting |
| Texas Oncology- Central South | Waco | Texas | 76712 | Recruiting |
| Texas Oncology-Central South | Waco | Texas | 76712 | Recruiting |
| Texas Oncology - Central South | Weslaco | Texas | 78596 | Recruiting |
| Blue Ridge Cancer Care | Blacksburg | Virginia | 24060 | Not yet recruiting |
| Oncology & Hematology Associates of Southwest Virginia Inc dba Blue Ridge Cancer Care | Salem | Virginia | 24153 | Not yet recruiting |
| Shenandoah Oncology, P.C. | Winchester | Virginia | 22601 | Not yet recruiting |
| American Oncology Network Vista Oncology Division-West office | Olympia | Washington | 98502 | Recruiting |
| American Oncology Network Vista Oncology Division-East office | Olympia | Washington | 98506 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 172 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07144280, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced May 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07144280 live on ClinicalTrials.gov.