Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
Public ClinicalTrials.gov record NCT07145255. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-label Phase 1/2 Dose Finding, Safety, and Pharmacokinetic Study of MBRC-201, an Antibody-drug Conjugate, in Advanced Refractory Solid Tumors
Study identification
- NCT ID
- NCT07145255
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- MBrace Therapeutics
- Industry
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Interventions
- ADC Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2, 2025
- Primary completion
- Sep 29, 2029
- Completion
- Dec 29, 2029
- Last update posted
- Feb 16, 2026
2025 – 2029
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | Recruiting |
| START, Midwest | Grand Rapids | Michigan | 49546 | Recruiting |
| START, Astera | East Brunswick | New Jersey | 08816 | Recruiting |
| NEXT, Dallas | Irving | Texas | 75039 | Recruiting |
| START San Antonio | San Antonio | Texas | 78229 | Recruiting |
| START, Mountain Region | West Valley City | Utah | 84119 | Recruiting |
| NEXT, Virginia | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07145255, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 16, 2026 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07145255 live on ClinicalTrials.gov.