eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Public ClinicalTrials.gov record NCT07177339. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Study of the Efficacy and Safety of Early Depemokimab Initiation as add-on Treatment in COPD Patients With Type 2 Inflammation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Depemokimab is being developed as a treatment for individuals with moderate to severe Chronic Obstructive Pulmonary Disorder (COPD). The aim of this study is to assess the efficacy and safety of early initiation of depemokimab as an add-on medicine in participants with moderate to severe COPD with type 2 inflammation.
Study identification
- NCT ID
- NCT07177339
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,196 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 19, 2025
- Primary completion
- Apr 29, 2029
- Completion
- Jun 7, 2029
- Last update posted
- Jul 27, 2026
2025 – 2029
United States locations
- U.S. sites
- 42
- U.S. states
- 16
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Newport Beach | California | 92663 | Recruiting |
| GSK Investigational Site | Lakewood | Colorado | 80228-1813 | Recruiting |
| GSK Investigational Site | Brandon | Florida | 33511 | Recruiting |
| GSK Investigational Site | Crystal River | Florida | 34429 | Recruiting |
| GSK Investigational Site | Doral | Florida | 33172 | Recruiting |
| GSK Investigational Site | Greenacres City | Florida | 33467 | Recruiting |
| GSK Investigational Site | Hialeah | Florida | 33012 | Recruiting |
| GSK Investigational Site | Hollywood | Florida | 33024 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33125 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33126 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33176 | Recruiting |
| GSK Investigational Site | Miami Lakes | Florida | 33016 | Recruiting |
| GSK Investigational Site | Orlando | Florida | 32825 | Recruiting |
| GSK Investigational Site | Cordele | Georgia | 31015 | Recruiting |
| GSK Investigational Site | Dunwoody | Georgia | 30350 | Recruiting |
| GSK Investigational Site | Boise | Idaho | 83702 | Recruiting |
| GSK Investigational Site | Bowling Green | Kentucky | 42101 | Recruiting |
| GSK Investigational Site | Lake Charles | Louisiana | 70605 | Recruiting |
| GSK Investigational Site | Shreveport | Louisiana | 71105 | Recruiting |
| GSK Investigational Site | Bangor | Maine | 04401 | Recruiting |
| GSK Investigational Site | Allen Park | Michigan | 48101 | Recruiting |
| GSK Investigational Site | Clarkston | Michigan | 48346 | Recruiting |
| GSK Investigational Site | Dearborn | Michigan | 48126 | Recruiting |
| GSK Investigational Site | Henderson | Nevada | 89052 | Recruiting |
| GSK Investigational Site | Las Vegas | Nevada | 89123 | Recruiting |
| GSK Investigational Site | Reno | Nevada | 89502 | Recruiting |
| GSK Investigational Site | Winston-Salem | North Carolina | 27103 | Recruiting |
| GSK Investigational Site | Edmond | Oklahoma | 73013 | Recruiting |
| GSK Investigational Site | DuBois | Pennsylvania | 15801 | Recruiting |
| GSK Investigational Site | West Chester | Pennsylvania | 19380 | Recruiting |
| GSK Investigational Site | Greenville | South Carolina | 29607 | Recruiting |
| GSK Investigational Site | Rock Hill | South Carolina | 29732 | Recruiting |
| GSK Investigational Site | Knoxville | Tennessee | 37919 | Recruiting |
| GSK Investigational Site | Dallas | Texas | 75254 | Recruiting |
| GSK Investigational Site | DeSoto | Texas | 75115 | Recruiting |
| GSK Investigational Site | Greenville | Texas | 75401 | Recruiting |
| GSK Investigational Site | Houston | Texas | 77058 | Recruiting |
| GSK Investigational Site | Houston | Texas | 77089 | Recruiting |
| GSK Investigational Site | Houston | Texas | 77090 | Recruiting |
| GSK Investigational Site | Katy | Texas | 77494 | Recruiting |
| GSK Investigational Site | Mesquite | Texas | 75149 | Recruiting |
| GSK Investigational Site | Stafford | Texas | 77477 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 79 non-U.S. sites.
Recently updated Pulmonary Disease, Chronic Obstructive trials
Other public records listing Pulmonary Disease, Chronic Obstructive. Sorted by last update posted; newest first. Not a recommendation.
- NCT07759245: A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) Not yet recruiting
- NCT07714252: Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD Not yet recruiting
- NCT05718102: Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD Active, not recruiting
- NCT04669743: Innate Immunity in Ozone-induced Airway Inflammation in COPD Active, not recruiting
- NCT06961214: Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2) Recruiting
- NCT05592847: A Study of the Effect of a Nurse Navigator Program on High Risk Patients Not yet recruiting
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07177339, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 27, 2026 · Synced Jul 28, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07177339 live on ClinicalTrials.gov.