A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT07196748. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-blind, Placebo-Controlled, Parallel Group, Multicenter Protocol in Adults With an Open Label Study in Adolescents to Evaluate the Efficacy and Safety of Induction and Maintenance Therapy With Icotrokinra in Participants With Moderately to Severely Active Ulcerative Colitis
Study identification
- NCT ID
- NCT07196748
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Enrollment
- 882 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2025
- Primary completion
- Jan 13, 2028
- Completion
- Jan 12, 2032
- Last update posted
- May 7, 2026
2025 – 2032
United States locations
- U.S. sites
- 53
- U.S. states
- 21
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AZ Gastro Care | Chandler | Arizona | 85206 | Recruiting |
| Research Solutions of Arizona | Litchfield Park | Arizona | 85340 | Recruiting |
| Mayo Clinic | Scottsdale | Arizona | 85259 | Recruiting |
| Clinnova Research | Anaheim | California | 92805 | Recruiting |
| Southern California Research Center | Coronado | California | 92118 | Recruiting |
| Om Research LLC | Lancaster | California | 93534 | Recruiting |
| TLC Clinical Research Inc | Los Angeles | California | 90048 | Recruiting |
| GastroIntestinal Bioscience | Los Angeles | California | 90067 | Recruiting |
| Om Research LLC 2 | Oxnard | California | 93030 | Recruiting |
| Clinical Applications Laboratories, Inc | San Diego | California | 92103 | Recruiting |
| Medical Associates Research Group, Inc. | San Diego | California | 92123 | Recruiting |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80907 | Recruiting |
| Nuvance Health Danbury Hospital | Danbury | Connecticut | 06810 | Recruiting |
| Connecticut Children's Medical Center | Hartford | Connecticut | 06106 | Recruiting |
| American Institute of Research | Cutler Bay | Florida | 33157 | Recruiting |
| Nature Coast Clinical Research | Inverness | Florida | 34452 | Recruiting |
| Florida Research Institute | Lakewood Rch | Florida | 34211 | Recruiting |
| GCP Clinical Research | Tampa | Florida | 33609 | Recruiting |
| Atlanta Gastroenterology Associates | Atlanta | Georgia | 30342 | Recruiting |
| Children's Center for Digestive Health Care | Atlanta | Georgia | 30342 | Recruiting |
| Gastroenterolgy Associates of Central GA | Macon | Georgia | 31201 | Recruiting |
| Cotton O'Neil Digestive Health Center | Topeka | Kansas | 66606 | Recruiting |
| Tri-State Gastroenterology Assoc | Crestview Hills | Kentucky | 41017 | Recruiting |
| Delta Research Partners, LLC | West Monroe | Louisiana | 71291 | Recruiting |
| Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | Recruiting |
| Woodholme Gastroenterology Associates | Glen Burnie | Maryland | 21061 | Recruiting |
| Westchester Putnam Gastroenterology | Carmel | New York | 10512 | Recruiting |
| Inflammatory Bowel Disease Center at NYU Langone | New York | New York | 10016 | Recruiting |
| Manhattan Clinical Research LLC | New York | New York | 10016 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Recruiting |
| Weill Cornell Medical College | New York | New York | 10065 | Recruiting |
| Lenox Hill Hospital | New York | New York | 10075 | Recruiting |
| New York Gastroenterology Associates | New York | New York | 10075 | Recruiting |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | Recruiting |
| Atrium Health | Charlotte | North Carolina | 28204 | Recruiting |
| Gastro Intestinal Research Institute of Northern Ohio LLC | Westlake | Ohio | 44145 | Suspended |
| Digestive Disease Specialists Inc | Oklahoma City | Oklahoma | 73114 | Recruiting |
| The Oregon Clinic | Portland | Oregon | 97220-9428 | Recruiting |
| Susquehanna Research Group | Harrisburg | Pennsylvania | 17110-3673 | Recruiting |
| Penn State Milton S Hershey Medical Ctr | Hershey | Pennsylvania | 17033 | Recruiting |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Jefferson Digestive Health Institute | Philadelphia | Pennsylvania | 19107 | Recruiting |
| University Gastroenterology | Providence | Rhode Island | 02905 | Recruiting |
| Digestive Disease Associates | Rock Hill | South Carolina | 29732 | Recruiting |
| The University of Texas at Austin | Austin | Texas | 78712 | Recruiting |
| DFW Clinical Trials | Carrollton | Texas | 75010 | Recruiting |
| Victorium Clinical Research | Houston | Texas | 77024 | Recruiting |
| Southern Star Research Institute, LLC | San Antonio | Texas | 78229 | Recruiting |
| GI Alliance Southlake | Southlake | Texas | 76092 | Recruiting |
| Tyler Research Institute, LLC | Tyler | Texas | 75701 | Recruiting |
| Gastroenterology Associates of Tidewater | Chesapeake | Virginia | 23320 | Recruiting |
| Blue Ridge Medical Research | Lynchburg | Virginia | 24502 | Recruiting |
| GI Alliance Tacoma | Tacoma | Washington | 98405 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07196748, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07196748 live on ClinicalTrials.gov.