A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Public ClinicalTrials.gov record NCT07199465. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, Open-label, Single-arm Study to Evaluate the Pharmacokinetics and Safety of Letermovir in Pediatric Kidney Transplant (KT) Recipients Less Than 18 Years of Age and Weighing Less Than 40 Kilograms
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Researchers are looking for a way to prevent cytomegalovirus (CMV) in children and adolescents who receive a kidney transplant (KT) and weigh less than 40 kilograms (88.2 pounds). The goals of the study are to: * Learn what happens to letermovir in the body over time * Learn about the safety of letermovir and if participants tolerate it
Study identification
- NCT ID
- NCT07199465
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 40 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Up to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 29, 2026
- Primary completion
- Apr 13, 2028
- Completion
- May 18, 2028
- Last update posted
- Jul 12, 2026
2026 – 2028
United States locations
- U.S. sites
- 18
- U.S. states
- 12
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham - School of Medicine - Pediatrics ( Site 0019) | Birmingham | Alabama | 35233 | Recruiting |
| UCLA Clinical & Translational Research Center (CTRC) ( Site 0006) | Los Angeles | California | 90095 | Recruiting |
| Lucile Packard Children's Hospital ( Site 0001) | Palo Alto | California | 94304 | Recruiting |
| University of California Davis Health ( Site 0023) | Sacramento | California | 95817 | Recruiting |
| UCSF Medical Center at Mission Bay ( Site 0017) | San Francisco | California | 94158 | Recruiting |
| Children's Hospital Colorado ( Site 0013) | Aurora | Colorado | 80045 | Recruiting |
| University of Miami School of Medicine ( Site 0021) | Miami | Florida | 33136 | Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago ( Site 0004) | Chicago | Illinois | 60611 | Recruiting |
| University of Michigan ( Site 0014) | Ann Arbor | Michigan | 48109 | Recruiting |
| M Health Fairview University of Minnesota Masonic Children's Hospital, West Bank ( Site 0007) | Minneapolis | Minnesota | 55454 | Recruiting |
| Mayo Clinic - Rochester ( Site 0015) | Rochester | Minnesota | 55905 | Recruiting |
| Morgan Stanley Children's Hospital ( Site 0018) | New York | New York | 10032 | Recruiting |
| Montefiore Einstein Center ( Site 0024) | The Bronx | New York | 10467 | Recruiting |
| Levine Children's Hospital ( Site 0022) | Charlotte | North Carolina | 28203 | Recruiting |
| Duke University-Pediatrics ( Site 0008) | Durham | North Carolina | 27110 | Recruiting |
| Cincinnati Children's Hospital Medical Center ( Site 0002) | Cincinnati | Ohio | 45229 | Recruiting |
| Children's Hospital of Philadelphia (CHOP) ( Site 0003) | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Texas Children's Hospital ( Site 0005) | Houston | Texas | 77030 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07199465, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 12, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07199465 live on ClinicalTrials.gov.