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Recruiting Phase 3 Interventional

A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

ClinicalTrials.gov ID: NCT07207369

Public ClinicalTrials.gov record NCT07207369. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Cohort-design, Double-blind, Randomized, Parallel-group, Controlled Study to Evaluate the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Atrophic acne scars are flat, indented or with an inverted center scars that develop at the endpoint of the normal healing process for acne. Acne scarring that remains after acne resolves has a significant impact on health related quality of life, including reduced self-esteem and embarrassment/self consciousness. ELAPR002f provides an immediate space-occupying effect for filling in the scar tissue. The purpose of this study is to assess how safe and effective ELAPR002f injectable gel is on adult participants with atrophic acne scars. ELAPR002f injectable gel is an investigational device being developed for the treatment of facial atrophic acne scars. There are 2 cohorts in this study. In Cohort 1, all participants will receive ELAPR002f injectable gel. In Cohort 2, participants are placed in 1 of 2 groups, called treatment arms. Each group receives a different treatment. There is a 1 in 4 chance that participants will be assigned to the saline active control group. Around 395 adult participants with moderate to severe atrophic acne scarring on both cheeks will be screened in the study in approximately 25 sites in the United States. Participants will receive 3 treatments over 2 months of intradermal injections of either ELAPR002f injectable gel or saline active control and will be followed for up to an additional 12 months. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.

Study identification

NCT ID
NCT07207369
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AbbVie
Industry
Enrollment
395 participants

Conditions and interventions

Conditions

Interventions

Device

Eligibility (public fields only)

Age range
22 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 23, 2025
Primary completion
Oct 31, 2029
Completion
Oct 31, 2029
Last update posted
Nov 23, 2025

2025 – 2029

United States locations

U.S. sites
10
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
Advanced Research Associates - Glendale /ID# 254961 Glendale Arizona 85308 Recruiting
Marcus Facial Plastic Surgery /ID# 275880 Redondo Beach California 90277 Recruiting
Pacific Clinical Innovations /ID# 256185 Vista California 92083-6030 Recruiting
DMR Research PLLC /ID# 256199 Westport Connecticut 06880 Recruiting
Hamilton Research, LLC /ID# 256925 Alpharetta Georgia 30022 Recruiting
Aesthetic Center at Woodholme /ID# 256197 Baltimore Maryland 21208-6391 Recruiting
The Center for Dermatology Cosmetics & Laser Surgery /ID# 256182 Mount Kisco New York 10549-3028 Recruiting
Wilmington Dermatology Center /ID# 256192 Wilmington North Carolina 28403 Recruiting
Austin Institute for Clinical Research - Pflugerville /ID# 256200 Pflugerville Texas 78660 Recruiting
SkinDC /ID# 254962 Arlington Virginia 22209 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07207369, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 23, 2025 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07207369 live on ClinicalTrials.gov.

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