CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Public ClinicalTrials.gov record NCT07207811. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CLEOPATTRA: Effects of NNC6019-0001 Versus Placebo on Cardiovascular Outcomes in Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy (ATTR-CM), which affects the heart. Participants will either receive NNC6019-0001 or a placebo (a treatment with no active medicine), and which one they get is decided by chance. Everyone in the study will continue receiving their usual heart treatments as recommended by their doctor.
Study identification
- NCT ID
- NCT07207811
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,280 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 1, 2025
- Primary completion
- Jun 28, 2029
- Completion
- Jun 28, 2029
- Last update posted
- Aug 18, 2026
2025 – 2029
United States locations
- U.S. sites
- 62
- U.S. states
- 28
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | Not yet recruiting |
| University of California San Diego (UCSD) - Sulpizio Cardiovascular Center (SCVC) | La Jolla | California | 92037 | Recruiting |
| Keck School of Medicine USC - Healthcare Consultation Center 2 (HCCII) | Los Angeles | California | 90033 | Not yet recruiting |
| Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute | Los Angeles | California | 90048 | Not yet recruiting |
| UCI Medical Center | Orange | California | 92868 | Not yet recruiting |
| Profound Research LLC at Southern California Heart Specialists | Pasadena | California | 91105 | Recruiting |
| University of California, San Francisco Medical Center | San Francisco | California | 94143 | Recruiting |
| NorthBay Clinical Research | Santa Rosa | California | 95405 | Recruiting |
| Lucile Packard Children's Hospital | Stanford | California | 94305 | Recruiting |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | Recruiting |
| MedStar Heart & Vascular Institute (MHVI) - MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010-3017 | Recruiting |
| UF Health Heart and Vascular Hospital | Gainesville | Florida | 32608 | Not yet recruiting |
| Northeast Georgia Heart Center, Pc (Nghc) | Gainesville | Georgia | 30501-3466 | Recruiting |
| The Queen's Medical Center | Honolulu | Hawaii | 96813 | Recruiting |
| Northwestern University Clinical and Translational Sciences Institute | Chicago | Illinois | 60611 | Recruiting |
| The University of Chicago Medicine | Chicago | Illinois | 60637 | Recruiting |
| Endeavor Health - Glenbrook Hospital | Glenview | Illinois | 60026 | Recruiting |
| Indiana University (IU) Health - Methodist Professional Center II | Indianapolis | Indiana | 46202 | Recruiting |
| LCMC - LSU University Medical Center New Orleans LCMC Center | New Orleans | Louisiana | 70112 | Recruiting |
| University of Maryland Medical Center (UMMC) - Children's Hospital (UMCH) | Baltimore | Maryland | 21201 | Recruiting |
| John Hopkins Medicine | Baltimore | Maryland | 21287 | Not yet recruiting |
| Tufts Medical Center | Boston | Massachusetts | 02111 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | Recruiting |
| Henry Ford Health | Detroit | Michigan | 48202 | Recruiting |
| Profound Research | Farmington Hills | Michigan | 48334 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Cardiology Associates Research, LLc | Tupelo | Mississippi | 38801 | Completed |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | Recruiting |
| Saint Louis University | St Louis | Missouri | 63110 | Not yet recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| North Shore University Hospital, Northwell Health | Manhasset | New York | 11030 | Recruiting |
| NYU Langone Health | New York | New York | 10016 | Recruiting |
| Weill Medical College Of Cornell University | New York | New York | 10021 | Recruiting |
| Mount Sinai Medical Center | New York | New York | 10029 | Recruiting |
| Columbia University Medical Center | New York | New York | 10032 | Recruiting |
| Laurelton Heart Specialist, PC | Rosedale | New York | 11422 | Recruiting |
| Yeshiva University - Albert Einstein College of Medicine - Montefiore Medical Center (MMC) | The Bronx | New York | 10467-2401 | Recruiting |
| Duke University Health System | Durham | North Carolina | 27750 | Not yet recruiting |
| The Carl and Edyth Lindner-Center for Research and Education at The Christ Hospital | Cincinnati | Ohio | 45219-2906 | Recruiting |
| Cleveland Clinic - Taussig Cancer Institute | Cleveland | Ohio | 44195 | Recruiting |
| OhioHealth Riverside Methodist Hospital | Columbus | Ohio | 43214 | Not yet recruiting |
| Oregon Health and Science University | Portland | Oregon | 97239 | Recruiting |
| Jefferson Health | Abington | Pennsylvania | 19001 | Recruiting |
| Penn State Milton S.Hershey Medical Center - Penn State Hershey Cancer Institute | Hershey | Pennsylvania | 17033 | Not yet recruiting |
| The Heart Group of Lancaster General Health | Lancaster | Pennsylvania | 17603 | Not yet recruiting |
| Penn Medicine: University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Prisma Health | Greenville | South Carolina | 29605 | Recruiting |
| Saint Thomas Health | Nashville | Tennessee | 37205 | Recruiting |
| Ascension Texas Cardiovascular Research Institute | Austin | Texas | 78705 | Recruiting |
| St. Davids Heart and Vascular | Austin | Texas | 78751 | Recruiting |
| Baylor Scott & White Research Institute - Annette C. and Harold C. Simmons Transplant Institute | Dallas | Texas | 75246 | Not yet recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390-9045 | Recruiting |
| Baylor St. Luke Medical Center | Houston | Texas | 77030 | Recruiting |
| Houston Methodist Hospital | Houston | Texas | 77030 | Recruiting |
| Baylor Scott & White The Heart Hospital | Plano | Texas | 75093 | Recruiting |
| Intermountain Healthcare - Intermountain Medical Center - C. DuWayne Schmidt Chest Clinic | Murray | Utah | 84107 | Recruiting |
| Inova Fairfax Hospital - Inova Heart and Vascular Institute | Falls Church | Virginia | 22042 | Recruiting |
| Sentara Cardiovascular Research Institute | Norfolk | Virginia | 23507 | Recruiting |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298 | Recruiting |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane | Washington | 99201 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 233 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07207811, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 18, 2026 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07207811 live on ClinicalTrials.gov.