Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women
Public ClinicalTrials.gov record NCT07209397. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Prospective, Multicenter, Double-Blind, Sham-Controlled Study to Assess the MORPHEUSV Radiofrequency (RF) Device in the Treatment of Female Patients With Idiopathic Overactive Bladder (OAB) With Urge Incontinence and/or Urge-Predominant Mixed Incontinence
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial is to learn if a vaginal radiofrequency (RF) device called MORPHEUSV works to treat overactive bladder (OAB) in women. Researchers also want to learn how safe the device is for this indication. This study will include women ages 22 to 80 who have had OAB symptoms for at least 6 months. The main questions it aims to answer are: Does the MORPHEUSV device lower the number of daily episodes of accidental urine leakage caused by urgency? Does it work better than a sham (placebo) treatment? Researchers will compare the MORPHEUSV device to a sham treatment to see how well it reduces symptoms of overactive bladder. Participants will: 1) Receive one session of either the MORPHEUSV or sham treatment. 2) Track their symptoms using a diary and questionnaires 3) Return for three to six follow-up visits over 12 months. This study is being conducted at multiple clinics in the United States.
Study identification
- NCT ID
- NCT07209397
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 202 participants
Conditions and interventions
Conditions
Interventions
- Detrusor nerve radiofrequency ablation Device
- Simulated (sham) detrusor nerve radiofrequency ablation Device
Device
Eligibility (public fields only)
- Age range
- 22 Years to 80 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 24, 2025
- Primary completion
- Jun 29, 2027
- Completion
- Nov 29, 2027
- Last update posted
- Jan 29, 2026
2025 – 2027
United States locations
- U.S. sites
- 9
- U.S. states
- 9
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford Medicine Department of Obstetrics & Gynecology | Palo Alto | California | 94304 | Not yet recruiting |
| MedStar Health Research Institute | Washington D.C. | District of Columbia | 20010 | Not yet recruiting |
| Advanced Specialty Research | Boise | Idaho | 83702 | Recruiting |
| University of Chicago Medicine Urogynecology | Chicago | Illinois | 60062 | Not yet recruiting |
| Cypress Medical Research Center | Wichita | Kansas | 67226 | Recruiting |
| Bay State Clinical Trials | Watertown | Massachusetts | 02472 | Recruiting |
| Urology Center, P.C. | Omaha | Nebraska | 68114 | Recruiting |
| UNLV Kirk Kerkorian School of Medicine Department of Gynecologic Surgery & Obstetrics | Las Vegas | Nevada | 89154 | Not yet recruiting |
| Atrium Health Wake Forest Female Pelvic Health Division | Winston-Salem | North Carolina | 27103 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07209397, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 29, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07209397 live on ClinicalTrials.gov.