ClinicalTrials.gov record
A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer
ClinicalTrials.gov ID: NCT07213804
Public ClinicalTrials.gov record NCT07213804. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 29, 2026, 11:00 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
FRAmework-01: A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) Versus Chemotherapy or Mirvetuximab Soravtansine in Platinum-Resistant Ovarian Cancer, and Sofetabart Mipitecan Plus Bevacizumab Versus Platinum-Based Chemotherapy Plus Bevacizumab in Platinum-Sensitive Ovarian Cancer.
Study identification
- NCT ID
- NCT07213804
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 1,080 participants
Conditions and interventions
Interventions
- Bevacizumab Drug
- Carboplatin Drug
- Gemcitabine Drug
- MIRV Drug
- Paclitaxel Drug
- Pegylated liposomal doxorubicin (PLD) Drug
- Sofetabart Mipitecan Drug
- Topotecan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 21, 2025
- Primary completion
- Mar 31, 2028
- Completion
- Jul 31, 2031
- Last update posted
- Apr 16, 2026
2025 – 2031
United States locations
- U.S. sites
- 80
- U.S. states
- 34
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Not yet recruiting |
| HonorHealth | Phoenix | Arizona | 85016 | Not yet recruiting |
| Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center | Burbank | California | 91505 | Not yet recruiting |
| City of Hope, Duarte | Duarte | California | 91010 | Not yet recruiting |
| Moores Cancer Center | La Jolla | California | 92093 | Not yet recruiting |
| UCLA Hematology/Oncology - Westwood (Building 100) | Los Angeles | California | 90095 | Not yet recruiting |
| Stanford Women's Cancer Center | Palo Alto | California | 94305 | Not yet recruiting |
| Kaiser Permanente Zion Medical Center | San Diego | California | 92120 | Not yet recruiting |
| Sansum Clinic | Santa Barbara | California | 93105 | Recruiting |
| Kaiser Permanente | Vallejo | California | 94589 | Not yet recruiting |
| Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | Not yet recruiting |
| AdventHealth Medical Group - Porter | Denver | Colorado | 80210 | Not yet recruiting |
| UConn Health | Farmington | Connecticut | 06030-8010 | Not yet recruiting |
| Broward Health Medical Center | Fort Lauderdale | Florida | 33316 | Not yet recruiting |
| Florida Cancer Specialist- South | Fort Myers | Florida | 33901 | Not yet recruiting |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | Not yet recruiting |
| University of Miami Hospital and Clinics, Sylvester Cancer Center | Miami | Florida | 33136 | Not yet recruiting |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | Not yet recruiting |
| AdventHealth Orlando | Orlando | Florida | 32803 | Not yet recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Not yet recruiting |
| Florida Cancer Specialist- East | West Palm Beach | Florida | 33401 | Not yet recruiting |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | Not yet recruiting |
| Nancy N. & J.C. Lewis Cancer and Research Pavillion | Savannah | Georgia | 31405 | Not yet recruiting |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | Not yet recruiting |
| Illinois Cancer Specialists | Arlington Heights | Illinois | 60005 | Recruiting |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | Not yet recruiting |
| Rush University Medical Center | Chicago | Illinois | 60612 | Not yet recruiting |
| OSF Saint Fracis Medical Center | Peoria | Illinois | 61637 | Not yet recruiting |
| Franciscan Health | Indianapolis | Indiana | 46237 | Not yet recruiting |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | Not yet recruiting |
| Norton Women's and Children's Hospital | Louisville | Kentucky | 40207 | Not yet recruiting |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | Not yet recruiting |
| Trials 365 | Shreveport | Louisiana | 71103 | Recruiting |
| Maine Medical Center - Scarborough Campus | Scarborough | Maine | 04074 | Not yet recruiting |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | Not yet recruiting |
| Sinai Hospital Of Baltimore | Baltimore | Maryland | 21215 | Not yet recruiting |
| University of Massachusetts Chan Medical School | Worcester | Massachusetts | 01605 | Not yet recruiting |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | Not yet recruiting |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | Not yet recruiting |
| Mayo Clinic in Rochester, Minnesota | Rochester | Minnesota | 55905 | Not yet recruiting |
| University of Missouri Hospital | Columbia | Missouri | 65212 | Not yet recruiting |
| HCA Midwest Kansas City, MidAmerica Division, Inc. | Kansas City | Missouri | 64132 | Not yet recruiting |
| Cox Medical Center North | Springfield | Missouri | 65802 | Not yet recruiting |
| The Center of Hope | Reno | Nevada | 89511 | Not yet recruiting |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | Not yet recruiting |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | Not yet recruiting |
| Optimum Clinical Research Group | Albuquerque | New Mexico | 87109 | Not yet recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Not yet recruiting |
| Northwell Health/ RJ Zuckerberg Cancer Center | Lake Success | New York | 11042 | Not yet recruiting |
| Perlmutter Cancer Center at NYU Langone Hospital - Long Island | Mineola | New York | 11501 | Recruiting |
| Laura and Isaac Perlmutter Cancer Center | New York | New York | 10016 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Not yet recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | Not yet recruiting |
| Duke Cancer Institute | Durham | North Carolina | 27710 | Not yet recruiting |
| Miami Valley Hospital South | Centerville | Ohio | 45459 | Recruiting |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | Not yet recruiting |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45242 | Recruiting |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | Not yet recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Not yet recruiting |
| The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T | Columbus | Ohio | 43210 | Not yet recruiting |
| The Mark H Zangmeister Center | Columbus | Ohio | 43219 | Not yet recruiting |
| ProMedica Flower Hospital | Sylvania | Ohio | 43560 | Not yet recruiting |
| USO - Oncology Associates of Oregon, P. C. | Eugene | Oregon | 97401 | Recruiting |
| Providence Portland Medical Center | Portland | Oregon | 97213 | Not yet recruiting |
| Kaiser Permanente Interstate Medical Office Central | Portland | Oregon | 97227 | Recruiting |
| Oregon Health and Science University | Portland | Oregon | 97239 | Not yet recruiting |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| Asplundh Cancer Pavilion | Willow Grove | Pennsylvania | 19090 | Not yet recruiting |
| Women & Infants Hospital | Providence | Rhode Island | 02905 | Not yet recruiting |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Not yet recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | Not yet recruiting |
| USO-Texas Oncology-Central/South Texas | Austin | Texas | 78731 | Recruiting |
| US Oncology | The Woodlands | Texas | 77380 | Recruiting |
| USO - Texas Oncology Gulf Coast | Webster | Texas | 77598-4420 | Recruiting |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | Not yet recruiting |
| Swedish Cancer Institute - Edmonds | Edmonds | Washington | 98026 | Not yet recruiting |
| Swedish Medical Center | Seattle | Washington | 98104 | Not yet recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Not yet recruiting |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 179 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07213804, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 16, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07213804 live on ClinicalTrials.gov.