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Recruiting Phase 3 Interventional

A Gaucher Disease Gene Therapy Trial With FLT201

ClinicalTrials.gov ID: NCT07223944

Public ClinicalTrials.gov record NCT07223944. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 7, 2026, 9:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Safety and Efficacy Trial of FLT201 Gene Therapy in Patients With Gaucher Disease Type 1

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is a Phase 3, non-randomized, multicenter, efficacy and safety study in adult patients with Gaucher disease Type 1, on stable treatment with enzyme replacement therapy (ERT) or substrate reduction therapy (SRT) for at least 2 years. The study aims to confirm the efficacy and safety of FLT201 in this population after discontinuation of ERT/SRT.

Study identification

NCT ID
NCT07223944
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Spur Therapeutics
Industry
Enrollment
45 participants

Conditions and interventions

Interventions

Genetic

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 6, 2026
Primary completion
Jun 30, 2028
Completion
Sep 30, 2032
Last update posted
Sep 2, 2026

2026 – 2032

United States locations

U.S. sites
16
U.S. states
12
U.S. cities
14
Facility City State ZIP Site status
Kaiser Permanente - CA Los Angeles California 90027 Recruiting
UCLA Health Los Angeles California 90095 Recruiting
University of California, San Francisco (UCSF) San Francisco California 94609 Recruiting
University of Colorado Anschutz Aurora Colorado 80045 Recruiting
Emory Healthcare Atlanta Georgia 30322 Recruiting
University of Iowa Health Care Iowa City Iowa 52242 Not yet recruiting
University of Minnesota Minneapolis Minnesota 55454 Recruiting
Hackensack University Medical Center Hackensack New Jersey 07601 Not yet recruiting
NYU Langone Health New York New York 10017 Recruiting
Columbia University New York New York 10032 Not yet recruiting
Duke University Medical Center Durham North Carolina 27710 Recruiting
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 Not yet recruiting
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 Recruiting
UPMC Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15224 Recruiting
University of Texas Southwestern Dallas Texas 75390 Recruiting
Lysosomal Rare Disorders Research and Treatment Center Fairfax Virginia 22030-6066 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07223944, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 2, 2026 · Synced Sep 7, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07223944 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →