Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
Public ClinicalTrials.gov record NCT07224581. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multinational, Multicenter Study With an Open-Label Phase 1b and a Randomized, Double-Blind, Placebo-Controlled Phase 3 Followed by an Open-Label Extension to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Radiprodil in Participants With GRIN-Related Neurodevelopmental Disorder
Study identification
- NCT ID
- NCT07224581
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- GRIN Therapeutics, Inc.
- Industry
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Interventions
- Radiprodil Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 1 Month to 18 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 4, 2026
- Primary completion
- Apr 30, 2027
- Completion
- Jun 30, 2028
- Last update posted
- Jul 16, 2026
2026 – 2028
United States locations
- U.S. sites
- 17
- U.S. states
- 13
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Health - Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | Recruiting |
| Lucile Packard Children's Hospital | Palo Alto | California | 94304 | Recruiting |
| Children's Hospital Colorado - Anschutz Medical Campus | Aurora | Colorado | 80045 | Recruiting |
| Children's National Hospital | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | Recruiting |
| Pediatric Neurology and Epilepsy | Winter Park | Florida | 32789 | Recruiting |
| Iowa Health Care - Pediatric Neurology & Specialty Clinic | Iowa City | Iowa | 52242 | Recruiting |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | Recruiting |
| Northeast Regional Epilepsy Group (NEREG) - Hackensack | Hackensack | New Jersey | 07601 | Recruiting |
| Columbia University - Harkness | New York | New York | 10032 | Recruiting |
| Duke Health-Duke Children's Hospital & Health Center | Durham | North Carolina | 27705 | Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | Not yet recruiting |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Child Neurology Consultants of Austin - South Austin | Austin | Texas | 78757 | Recruiting |
| The University of Texas Southwestern Medical Center (UTSW) | Dallas | Texas | 75390 | Recruiting |
| UTHealth Houston | Houston | Texas | 77030 | Recruiting |
| Seattle Children's Hospital | Seattle | Washington | 98105 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07224581, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 16, 2026 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07224581 live on ClinicalTrials.gov.