Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR
Public ClinicalTrials.gov record NCT07227675. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR Continued Access Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The COAPT Continued Access Study (CAS) is an extension of the COAPT RCT under the same IDE (G120024). COAPT CAS was a single-arm, prospective, multicenter continued access registry that enrolled heart failure patients with secondary mitral regurgitation who remained symptomatic despite optimal guideline-directed medical therapy (GDMT). The objective of the COAPT CAS is to continue the evaluation of safety and effectiveness of the MitraClip NT System under more "real world" conditions in patients who meet the COAPT inclusion/exclusion criteria and who have national Medicare coverage by the Centers for Medicare and Medicaid Services (CMS).
Study identification
- NCT ID
- NCT07227675
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 162 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 23, 2017 (Actual)
- Primary completion
- Mar 14, 2019 (Actual)
- Completion
- Mar 31, 2024 (Actual)
- Last update posted
- Nov 13, 2025
2017 – 2024
United States locations
- U.S. sites
- 32
- U.S. states
- 18
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scripps Green Hospital | La Jolla | California | 92037 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| Stanford Hospital and Clinics | Stanford | California | 94305 | — |
| University of Colorado Hospital | Denver | Colorado | 80045 | — |
| Mount Sinai Medical Center | Miami | Florida | 33140 | — |
| Tallahassee Memorial Hospital | Tallahassee | Florida | 32308 | — |
| Piedmont Hospital Atlanta | Atlanta | Georgia | 30309 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Barnes Jewish Hospital | St Louis | Missouri | 63110 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Columbia University Medical Center / New York Presbyterian Hospital | New York | New York | 10032 | — |
| St. Francis Hospital | Roslyn | New York | 11576 | — |
| Atrium Health Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Oklahoma Heart Hospital | Oklahoma City | Oklahoma | 73120 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Shadyside Hospital | Pittsburgh | Pennsylvania | 15232 | — |
| Seton Medical Center Austin | Austin | Texas | 78705 | — |
| Baylor Heart and Vascular Hospital | Dallas | Texas | 75204 | — |
| The heart hospital baylor plano | Plano | Texas | 75093 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23284 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07227675, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 13, 2025 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07227675 live on ClinicalTrials.gov.