Longitudinal Natural History Study of Retinal Function in Eyes of Patients With Diabetes
Public ClinicalTrials.gov record NCT07270133. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A considerable hurdle to the development of novel, more effective therapies for diabetic retinal disease is the limited number of primary endpoints available for use in regulatory trials. Current endpoints necessitate long trial durations and a greater number of participants to show efficacy. Thus, a better understanding of the structural and functional changes in the retina occurring in people with diabetes is essential for developing primary endpoints and validating surrogate and clinical endpoints.
Study identification
- NCT ID
- NCT07270133
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 450 participants
Conditions and interventions
Conditions
Interventions
- Visual Acuity Diagnostic Test
- Reading Speed Diagnostic Test
- Visual Field testing Diagnostic Test
- Contrast sensitivity Diagnostic Test
- Electroretinography (ERG) and pupillography in light- and dark-adapted states Diagnostic Test
- Ultrawide field-color photograph Diagnostic Test
- Ultrawide field-Fluorescein angiogram Diagnostic Test
- Optical coherence tomography Diagnostic Test
- Optical coherence tomography- Angiography Other
Diagnostic Test · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2026
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2032
- Last update posted
- Aug 19, 2026
2026 – 2032
United States locations
- U.S. sites
- 4
- U.S. states
- 4
- U.S. cities
- 4
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southeast Retina Center, P.C. | Augusta | Georgia | 30909 | Recruiting |
| Boston Medical Center Corporation | Boston | Massachusetts | 02118 | Recruiting |
| Henry Ford Health System | Detroit | Michigan | 48202 | Recruiting |
| Retina-Vitreous Consultants, Inc. | Monroeville | Pennsylvania | 15146 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07270133, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 19, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07270133 live on ClinicalTrials.gov.