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Active, not recruiting Phase 2 Interventional

Taldefgrobep Alfa in Adults With Overweight and Obesity

ClinicalTrials.gov ID: NCT07281495

Public ClinicalTrials.gov record NCT07281495. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:23 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Multiple Dose Study With Open-Label Extension to Assess the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Taldefgrobep Alfa in Adults Living With Overweight and Obesity

Study identification

NCT ID
NCT07281495
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Biohaven Therapeutics Ltd.
Industry
Enrollment
150 participants

Conditions and interventions

Interventions

  • Taldefgrobep Alfa Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 23, 2025
Primary completion
Aug 31, 2026
Completion
Aug 31, 2026
Last update posted
Mar 19, 2026

2025 – 2026

United States locations

U.S. sites
20
U.S. states
11
U.S. cities
20
Facility City State ZIP Site status
Site-001 Chula Vista California 91911
Site-014 Montclair California 97163
Site-011 Sacramento California 95821
Site-018 Tustin California 92780
Site-020 Orlando Florida 32804
Site-008 Palm Springs Florida 33461
Site-015 St. Petersburg Florida 33704
Site-007 Chicago Illinois 60625
Site-016 Indianapolis Indiana 46254
Site-010 Baton Rouge Louisiana 70808
Site-009 Metairie Louisiana 70006
Site-006 City of Saint Peters Missouri 63303
Site-003 Springfield Missouri 65807
Site-019 Monroe North Carolina 28112
Site-002 Fargo North Dakota 58104
Site-017 North Charleston South Carolina 29405
Site-005 Austin Texas 78745
Site-012 McKinney Texas 75069
Site-013 San Antonio Texas 78229
Site-004 Arlington Virginia 22205

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07281495, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 19, 2026 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07281495 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →