A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Public ClinicalTrials.gov record NCT07281937. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Phase 2b Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The aim of this study is to evaluate the efficacy of VRB-101 for body weight reduction compared to placebo in participants who have obesity or overweight with weight-related comorbidities.
Study identification
- NCT ID
- NCT07281937
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 206 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 25, 2025 (Actual)
- Primary completion
- Jul 23, 2026 (Actual)
- Completion
- Jul 23, 2026 (Actual)
- Last update posted
- Aug 17, 2026
2025 – 2026
United States locations
- U.S. sites
- 22
- U.S. states
- 15
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Study Site 103 | Anniston | Alabama | 36207 | — |
| Clinical Study Site 109 | Cullman | Alabama | 35055 | — |
| Clinical Study Site 110 | Phoenix | Arizona | 85028 | — |
| Clinical Study Site 113 | Little Rock | Arkansas | 72205 | — |
| Clinical Study Site 111 | Anaheim | California | 92801 | — |
| Clinical Study Site 107 | Montclair | California | 91763 | — |
| Clinical Study Site 118 | Tarzana | California | 91356 | — |
| Clinical Study Site 119 | Decatur | Georgia | 30030 | — |
| Clinical Study Site 116 | West Des Moines | Iowa | 50266 | — |
| Clinical Study Site 106 | Wichita | Kansas | 67207 | — |
| Clinical Study Site 122 | Southfield | Michigan | 48076 | — |
| Clinical Study Site 121 | Omaha | Nebraska | 68134 | — |
| Clinical Study Site 117 | Binghamton | New York | 13905 | — |
| Clinical Study Site 101 | Rochester | New York | 14609 | — |
| Clinical Study Site 120 | Charlotte | North Carolina | 28210 | — |
| Clinical Study Site 108 | Monroe | North Carolina | 28112 | — |
| Clinical Study Site 105 | Norman | Oklahoma | 73069 | — |
| Clinical Study Site 114 | Duncansville | Pennsylvania | 16635 | — |
| Clinical Study Site 115 | Knoxville | Tennessee | 37909 | — |
| Clinical Study Site 112 | Dallas | Texas | 75251 | — |
| Clinical Study Site 102 | San Antonio | Texas | 78229 | — |
| Clinical Study Site 104 | San Antonio | Texas | 78240 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07281937, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 17, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07281937 live on ClinicalTrials.gov.