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Recruiting Phase 2 Interventional

Phentermine's Impact on Treatment in Teens

ClinicalTrials.gov ID: NCT07282340

Public ClinicalTrials.gov record NCT07282340. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 11:06 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phentermine's Impact on Treatment in Teens (PhITT): A Randomized Placebo-Controlled Trial of Phentermine for Adolescents With Obesity

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

PhITT is a Phase IIb, multicenter, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of phentermine (16 mg daily) in adolescents aged 12 to \<18 years with obesity. Conducted across approximately 10 sites within the IDeA States Pediatric Clinical Trials Network (ISPCTN), the study aims to enroll up to 240 participants and then randomize up to 198 who meet eligibility criteria, randomized in a 2:1 ratio to phentermine or placebo over a 52-week treatment period, followed by a 2-week withdrawal assessment.

Study identification

NCT ID
NCT07282340
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Russell McCulloh, MD
Network
Enrollment
240 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
12 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2, 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027
Last update posted
Aug 9, 2026

2026 – 2028

United States locations

U.S. sites
6
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
Pennington Biomedical Research Center Baton Rouge Louisiana 70808 Recruiting
Children's Mercy Hospital Kansas City Missouri 64108 Recruiting
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756 Recruiting
University of New Mexico Health Sciences Center Albuquerque New Mexico 87131 Recruiting
The University of Oklahoma Health Sciences Children's Hospital Oklahoma City Oklahoma 73104 Recruiting
Prisma Health-Midlands Children's Hospital Columbia South Carolina 29203 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07282340, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 9, 2026 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07282340 live on ClinicalTrials.gov.

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